Jianfeng Yang
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View article: Case Report: Mimicking benignity: hepatic sinusoidal metastasis masquerading as diffuse liver disease in small cell lung cancer
Case Report: Mimicking benignity: hepatic sinusoidal metastasis masquerading as diffuse liver disease in small cell lung cancer Open
Background Small cell lung cancer is extremely aggressive. Although liver metastasis is common, cases of diffuse intra-sinusoidal metastasis leading to liver failure and death are quite rare. Case presentation This paper reports a case of …
View article: Structural Design and Dynamic Analysis of a Deep Space Exploration Zoom Camera
Structural Design and Dynamic Analysis of a Deep Space Exploration Zoom Camera Open
Space optical cameras serve as vital tools for solar observation, mostly employing fixed-focus systems to reduce moving parts and increase system stability. However, with increasing demands for observation, maintaining consistent image siz…
View article: Reprogramming of fatty acid metabolism: a hidden force regulating the occurrence and progression of cholangiocarcinoma
Reprogramming of fatty acid metabolism: a hidden force regulating the occurrence and progression of cholangiocarcinoma Open
Cholangiocarcinoma (CCA) is a malignant tumor that originates from the bile duct epithelium and with a poor outcome due to lack of effective early diagnostic methods. Surgical resection is the preferred method for cure, but treatment optio…
View article: Updated review of research on the role of the gut microbiota and microbiota-derived metabolites in acute pancreatitis progression and inflammation-targeted therapy
Updated review of research on the role of the gut microbiota and microbiota-derived metabolites in acute pancreatitis progression and inflammation-targeted therapy Open
Acute pancreatitis (AP) is characterized by autodigestion of the pancreas, and some patients may rapidly progress to systemic inflammation, pancreatic necrosis, and multi-organ failure. Numerous studies have detailed the bidirectional comm…
View article: Novel biotargets of colorectal cancer peritoneal metastasis
Novel biotargets of colorectal cancer peritoneal metastasis Open
Introduction Peritoneal metastasis often predicts advanced progression and a poor prognosis in colorectal cancer (CRC). However, peritoneal metastases are extremely difficult to predict or diagnose by routine diagnostic methods. Material a…
View article: Carbapenem-resistant Enterobacterales sepsis following endoscopic retrograde cholangiopancreatography: risk factors for 30-day all-cause mortality and the development of a nomogram based on a retrospective cohort
Carbapenem-resistant Enterobacterales sepsis following endoscopic retrograde cholangiopancreatography: risk factors for 30-day all-cause mortality and the development of a nomogram based on a retrospective cohort Open
Background Endoscopic retrograde cholangiopancreatography (ERCP) has become a routine endoscopic procedure that is essential for diagnosing and managing various conditions, including gallstone extraction and the treatment of bile duct and …
View article: Cholangioscopy-guided laser ablation for intraductal papillary neoplasm of bile duct
Cholangioscopy-guided laser ablation for intraductal papillary neoplasm of bile duct Open
A 65-year-old man with a history of metastatic bladder cancer was admitted with jaundice. Blood tests revealed a cholestatic pattern of liver function, hyperbilirubinemia, and deranged clotting profile. Computed tomography and magnetic res…
View article: Causal relationship between immune cells and osteoarthritis: a two-sample Mendelian randomization study
Causal relationship between immune cells and osteoarthritis: a two-sample Mendelian randomization study Open
Objective:Little research hasn't been done on the connection between immune cells and osteoarthritis. To investigate the pathogenic and protective roles of immune cells in osteoarthritis risk, Mendelian randomization was employed in this s…
View article: Gut microbiota influence acute pancreatitis through inflammatory proteins: a Mendelian randomization analysis
Gut microbiota influence acute pancreatitis through inflammatory proteins: a Mendelian randomization analysis Open
Background/Aim We employed Mendelian randomization (MR) analysis to investigate the causal relationship between the gut microbiota, acute pancreatitis, and potential inflammatory proteins. Methods The data for gut microbiota, acute pancrea…
View article: LC3-dependent extracellular vesicles promote M-MDSC accumulation and immunosuppression in colorectal cancer
LC3-dependent extracellular vesicles promote M-MDSC accumulation and immunosuppression in colorectal cancer Open
For a long time, myeloid-derived suppressor cells (MDSCs) dilated in circulation system of colorectal cancer (CRC) patients have been puzzling clinicians. Various evidence shows that MDSCs constitute the bulk of immunosuppression in CRC, w…
View article: Potential missed opportunities for diagnosis of lymphoepithelioma-like intrahepatic cholangiocarcinoma: report of a rare case
Potential missed opportunities for diagnosis of lymphoepithelioma-like intrahepatic cholangiocarcinoma: report of a rare case Open
Lymphoepithelioma-like intrahepatic cholangiocarcinoma (LEL-ICC) is a rare distinctive variant of liver cancer with unique epidemiological and pathological characteristics, including dense lymphocyte infiltration. We herein describe a 67-y…
View article: Disulfiram enhances the antitumor activity of cisplatin by inhibiting the Fanconi anemia repair pathway
Disulfiram enhances the antitumor activity of cisplatin by inhibiting the Fanconi anemia repair pathway Open
A series of chemotherapeutic drugs that induce DNA damage, such as cisplatin (DDP), are standard clinical treatments for ovarian cancer, testicular cancer, and other diseases that lack effective targeted drug therapy. Drug resistance is on…
View article: Development and Assessment of a Novel Predictive Nomogram to Predict the Risk of Secondary CR-GNB Bloodstream Infections among CR-GNB Carriers in the Gastroenterology Department: A Retrospective Case–Control Study
Development and Assessment of a Novel Predictive Nomogram to Predict the Risk of Secondary CR-GNB Bloodstream Infections among CR-GNB Carriers in the Gastroenterology Department: A Retrospective Case–Control Study Open
Background: With the number of critically ill patients increasing in gastroenterology departments (GEDs), infections associated with Carbapenem-resistant Gram-negative bacteria (CR-GNB) are of great concern in GED. However, no CR-GNB blood…
View article: Identification of novel immune-related targets mediating disease progression in acute pancreatitis
Identification of novel immune-related targets mediating disease progression in acute pancreatitis Open
Introduction Acute pancreatitis (AP) is an inflammatory disease with very poor outcomes. However, the order of induction and coordinated interactions of systemic inflammatory response syndrome (SIRS) and compensatory anti-inflammatory resp…
View article: Risk Factors for Carbapenem Resistant Gram Negative Bacteria (CR-GNB) Carriage Upon Admission to the Gastroenterology Department in a Tertiary First Class Hospital of China: Development and Assessment of a New Predictive Nomogram
Risk Factors for Carbapenem Resistant Gram Negative Bacteria (CR-GNB) Carriage Upon Admission to the Gastroenterology Department in a Tertiary First Class Hospital of China: Development and Assessment of a New Predictive Nomogram Open
With an estimate of individual risk using the nomogram developed in this study, clinicians and nurses can take more timely infection preventive measures on isolation, cohorting and medical interventions.
View article: Features of non-stenotic carotid plaque on computed tomographic angiography in patients with embolic stroke of undetermined source
Features of non-stenotic carotid plaque on computed tomographic angiography in patients with embolic stroke of undetermined source Open
Purpose Embolic stroke of undetermined source (ESUS) is a subset of cryptogenic stroke constituting a large proportion of acute ischemic strokes. This study aimed to assess the features of non-stenotic carotid plaque (<50%) on computed …
View article: Early Versus Delayed Enteral Feeding in Predicted Severe Acute Gallstone Pancreatitis: A Retrospective Study
Early Versus Delayed Enteral Feeding in Predicted Severe Acute Gallstone Pancreatitis: A Retrospective Study Open
Background The optimal timing of enteral nutrition (EN) initiation in predicted severe acute gallstone pancreatitis (SAGP) and its influence on disease outcomes are not well known. Methods We conducted a retrospective study of patients wit…
View article: Establishment of a Novel Nine-gene Signature for the Prognosis of Cholangiocarcinoma
Establishment of a Novel Nine-gene Signature for the Prognosis of Cholangiocarcinoma Open
Background: Cholangiocarcinoma (CCA) is a rare malignant carcinoma characterized by high mortality, challenging diagnosis, and poor prognosis. A powerful prediction biomarker is urgently needed for the early diagnosis and individualized tr…
View article: Comparing the diagnostic performance of radiotracers in prostate cancer biochemical recurrence: a systematic review and meta-analysis
Comparing the diagnostic performance of radiotracers in prostate cancer biochemical recurrence: a systematic review and meta-analysis Open
Objectives To systematically assess the early detection rate of biochemical prostate cancer recurrence using choline, fluciclovine, and PSMA. Methods Under the guidance of the Preferred Reporting Items for Systematic reviews and Meta-Analy…
View article: Resection Of Giant Malignant Solitary Fibrous Pleural Tumor After Interventional Embolization: A Case Report And Literature Review
Resection Of Giant Malignant Solitary Fibrous Pleural Tumor After Interventional Embolization: A Case Report And Literature Review Open
Background: Solitary fibrous tumor of the pleura (SFTP) is rare mesenchymal tumors that arise at a variety of sites and typically originate from the pleura. Most patients of SFTP are usually asymptomatic unless the tumor is large. Only abo…
View article: A Dynamic Follow-Up of Pneumonia Caused by Coronavirus Disease 2019 (COVID-19) on CT Scan
A Dynamic Follow-Up of Pneumonia Caused by Coronavirus Disease 2019 (COVID-19) on CT Scan Open
: Coronavirus disease (COVID-19) broke out in Wuhan, China. It is a highly contagious respiratory disease, the basic reproductive number (RO value) for COVID-19 has been reported as 2.68 with an epidemic doubling time of 6.4 days. In this …
View article: Clinicopathological features of primary thyroid leiomyosarcoma without Epstein‑Barr virus infection: A case report
Clinicopathological features of primary thyroid leiomyosarcoma without Epstein‑Barr virus infection: A case report Open
Primary thyroid leiomyosarcoma (LMS) is a rare tumor type with an unusual location, the diagnosis is based entirely on histological and immunohistochemical evaluations. In the present study, a rare case of a 74-year-old female patient who …
View article: Imaging findings of gastric plexiform fibromyxoma with a cystic change
Imaging findings of gastric plexiform fibromyxoma with a cystic change Open
As far as we know, a gastric PF with a remarkable cystic change has never been reported. Additionally, the tumor exhibited a progressive enhancement pattern which is a characteristic radiographic feature in our case. Our report may help in…
View article: [Application of dynamic-contrast enhanced magnetic resonance pharmacokinetic models in differential diagnosis of cellular uterine leiomyoma].
[Application of dynamic-contrast enhanced magnetic resonance pharmacokinetic models in differential diagnosis of cellular uterine leiomyoma]. Open
Three pharmacokinetics models can be used in the differentiation of cellular uterine leiomyoma from other types of uterine leiomyoma. Ktrans of the ET model has higher sensitivity and specificity in differential diagnosis of cellular uteri…
View article: Dual-input two-compartment pharmacokinetic model of dynamic contrast-enhanced magnetic resonance imaging in hepatocellular carcinoma
Dual-input two-compartment pharmacokinetic model of dynamic contrast-enhanced magnetic resonance imaging in hepatocellular carcinoma Open
A dual-input two-compartment pharmacokinetic model (a dual-input extended Tofts model and a dual-input 2CXM) can be used in assessing the microvascular physiopathological properties before the treatment of advanced HCC. The dual-input exte…