J. Li
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View article: Letter to the editor “Protective immune cell phenotypes and breast cancer risk: insights from mendelian randomization and meta-analysis”
Letter to the editor “Protective immune cell phenotypes and breast cancer risk: insights from mendelian randomization and meta-analysis” Open
View article: Spinal Metastasis from Supratentorial Glioblastoma: A Registry-Based Case Series and a Review of the Literature
Spinal Metastasis from Supratentorial Glioblastoma: A Registry-Based Case Series and a Review of the Literature Open
Background: Spinal metastasis is a rare complication of supratentorial glioblastoma. We report the clinical features and prognosis of this phenomenon and review the relevant literature. Methods: This is a territory-wide, multicentre, retro…
View article: CT-Occult Primary Benign Tracheobronchial Neoplasms: A Single-Center 40-Case Clinicopathologic Series
CT-Occult Primary Benign Tracheobronchial Neoplasms: A Single-Center 40-Case Clinicopathologic Series Open
Primary benign tracheobronchial neoplasms are commonly small and undetectable by CT of the chest. Coupled with nonspecific symptoms this demands a high index of suspicion including in patients with coexisting conditions such as TB. Definit…
View article: Development and validation of a machine learning-based early warning system for predicting venous thromboembolism risk in hospitalized lymphoma patients undergoing chemotherapy: a multicenter and retrospective cohort study
Development and validation of a machine learning-based early warning system for predicting venous thromboembolism risk in hospitalized lymphoma patients undergoing chemotherapy: a multicenter and retrospective cohort study Open
Background Lymphoma patients hospitalized for chemotherapy are at increased risk of venous thromboembolism (VTE) due to prolonged treatment and bed rest. Early prediction of VTE in this group remains challenging. This study aimed to develo…
View article: A novel nomogram for survival prediction in renal cell carcinoma patients with brain metastases: an analysis of the SEER database
A novel nomogram for survival prediction in renal cell carcinoma patients with brain metastases: an analysis of the SEER database Open
Background Existing research on the development of prognostic models for renal cell carcinoma (RCC) patients with brain metastases (BM) remains limited. This study aimed to develop a prognostic prediction model for RCC patients with BM and…
View article: Lightweight insulator target detection algorithm based on improved YOLOX
Lightweight insulator target detection algorithm based on improved YOLOX Open
View article: Enhancing noninvasive pancreatic cystic neoplasm diagnosis with multimodal machine learning
Enhancing noninvasive pancreatic cystic neoplasm diagnosis with multimodal machine learning Open
View article: Oxymatrine Inhibits PKM2-Mediated Glycolysis and Enhances Cisplatin Sensitivity in Bladder Cancer
Oxymatrine Inhibits PKM2-Mediated Glycolysis and Enhances Cisplatin Sensitivity in Bladder Cancer Open
View article: The relationship between the triglyceride-glucose (TyG) index and all-cause mortality in ICU patients with primary hypertension: a retrospective study
The relationship between the triglyceride-glucose (TyG) index and all-cause mortality in ICU patients with primary hypertension: a retrospective study Open
Background Hypertension includes both primary hypertension and secondary hypertension. Primary hypertension is the most common type of hypertension, accounting for 90% to 95% of all cases, with a complex and not fully understood pathogenes…
View article: Cardiovascular adverse events and immune-related adverse events associated with PD-1/PD-L1 inhibitors for head and neck squamous cell carcinoma (HNSCC)
Cardiovascular adverse events and immune-related adverse events associated with PD-1/PD-L1 inhibitors for head and neck squamous cell carcinoma (HNSCC) Open
View article: Potential antitumor activity of triptolide and its derivatives: Focused on gynecological and breast cancers
Potential antitumor activity of triptolide and its derivatives: Focused on gynecological and breast cancers Open
Cancer remains one of the greatest global health concerns. This is especially true for gynecological cancers, which include cervical, ovarian, and endometrial cancers, and breast cancer. Natural products used for cancer treatment offer som…
View article: Ectopic pleural thymoma with T-cell lymphocytosis and bone metastasis: a case report
Ectopic pleural thymoma with T-cell lymphocytosis and bone metastasis: a case report Open
View article: Independent association between prostate-specific antigen nadir and PSA progression-free survival in first-line abiraterone acetate treatment in castration-resistant prostate cancer patients: a pilot study
Independent association between prostate-specific antigen nadir and PSA progression-free survival in first-line abiraterone acetate treatment in castration-resistant prostate cancer patients: a pilot study Open
Background There is limited evidence regarding the correlation between prostate-specific antigen (PSA) kinetics and clinical outcomes. Therefore, after regulating other covariates, we studied patients with castration-resistant prostate can…
View article: Cardiovascular Adverse Events and Immune-related Adverse Events Associated with PD-1/PD-L1 Inhibitors for Head and Neck Squamous Cell Carcinoma (HNSCC): A Real-world study (RWS) by Bayesian Disproportional Analysis Based on the FDA Adverse Event Reporting System (FAERS)
Cardiovascular Adverse Events and Immune-related Adverse Events Associated with PD-1/PD-L1 Inhibitors for Head and Neck Squamous Cell Carcinoma (HNSCC): A Real-world study (RWS) by Bayesian Disproportional Analysis Based on the FDA Adverse Event Reporting System (FAERS) Open
Background: Although certain literature had revealed meager clues on the potential cardiovascular risk and immune-related adverse events (irAEs) risk associated with PD-1/PD-L1 inhibitors in the treatment of Head and Neck Squamous Cell Car…
View article: Sildenafil Citrate Induces Prostatic Hyperplasia in BPH Model Rats and Aged Rats
Sildenafil Citrate Induces Prostatic Hyperplasia in BPH Model Rats and Aged Rats Open
Erectile dysfunction (ED), a prevalent disease among middle-aged and elderly males, significantly impacts both patient and partner quality of life. Phosphodiesterase type 5 inhibitor (PDE5i) represents an effective therapeutic method for E…
View article: 194MO Phase II study of low-dose radiation (LDRT) plus durvalumab (D) and etoposide/platinum (EP) as first-line treatment in ES-SCLC (LEAD): Efficacy and safety results
194MO Phase II study of low-dose radiation (LDRT) plus durvalumab (D) and etoposide/platinum (EP) as first-line treatment in ES-SCLC (LEAD): Efficacy and safety results Open
The phase III CASPIAN trial established D+ EP as first-line (1L) standard of care of ES-SCLC. However, most patients (pts) do not experience durable clinical benefit. LDRT could induce local control, and exert synergistic efficacy with Imm…
View article: 1MO A phase IIIb study of savolitinib in patients with locally advanced or metastatic NSCLC harboring MET exon 14 mutation
1MO A phase IIIb study of savolitinib in patients with locally advanced or metastatic NSCLC harboring MET exon 14 mutation Open
Savolitinib is a potent and highly selective oral MET tyrosine-kinase inhibitor, approved in China for the treatment of NSCLC patients (pts) that have progressed following prior systemic therapy or are unable to receive chemotherapy with M…
View article: [Effectiveness Evaluation of Low-dose Spiral Computed Tomography
for Lung Cancer Screening in Minhang District of Shanghai].
[Effectiveness Evaluation of Low-dose Spiral Computed Tomography
for Lung Cancer Screening in Minhang District of Shanghai]. Open
The participants of the screening program are at high-risk of lung cancer. LDCT favors the early-detection of lung cancer and improves 5-year survival of the screened cases, indicating a great potential of LDCT in reducing the disease burd…
View article: OA21.03 A Phase 3b Study of 1L Savolitinib in Patients with Locally Advanced or Metastatic NSCLC Harboring MET Exon 14 Mutation
OA21.03 A Phase 3b Study of 1L Savolitinib in Patients with Locally Advanced or Metastatic NSCLC Harboring MET Exon 14 Mutation Open
View article: EP12.02-12 Matching-Adjusted Indirect Comparison (MAIC): Entrectinib versus Crizotinib in Asian Patients with ROS1+ NSCLC
EP12.02-12 Matching-Adjusted Indirect Comparison (MAIC): Entrectinib versus Crizotinib in Asian Patients with ROS1+ NSCLC Open
View article: Next generation sequencing predicting clinical effect of immunotherapy on adult rhabdomyosarcoma patient: A case report
Next generation sequencing predicting clinical effect of immunotherapy on adult rhabdomyosarcoma patient: A case report Open
Rationale: Rhabdomyosarcoma (RMS) is a rare sarcoma that rarely occurs in adults and accounts for only 1% of all adult tumors. The standard treatment for RMS is surgical resection, radiotherapy, and chemotherapy. Patient concerns: Adult pa…
View article: 17P Safety and tolerability of sintilimab (sint) combination therapy in patients with advanced or recurrent non-small cell lung cancer (NSCLC): Pooled safety analysis of ORIENT 11 and ORIENT 12 studies
17P Safety and tolerability of sintilimab (sint) combination therapy in patients with advanced or recurrent non-small cell lung cancer (NSCLC): Pooled safety analysis of ORIENT 11 and ORIENT 12 studies Open
View article: P45.08 Lorlatinib for Previously Treated ALK-Positive Advanced NSCLC: Primary Efficacy and Safety Data from a Phase 2 Study in China
P45.08 Lorlatinib for Previously Treated ALK-Positive Advanced NSCLC: Primary Efficacy and Safety Data from a Phase 2 Study in China Open
View article: P76.47 Molecular Characteristics and Response to Diverse EGFR TKIs of NSCLC Patients Harboring EGFR E709-T710delinsX
P76.47 Molecular Characteristics and Response to Diverse EGFR TKIs of NSCLC Patients Harboring EGFR E709-T710delinsX Open
View article: P21.10 Real-World Treatment Patterns in Chinese Stage III NSCLC Patients - A Prospective, Non-Interventional Study (MOOREA trial)
P21.10 Real-World Treatment Patterns in Chinese Stage III NSCLC Patients - A Prospective, Non-Interventional Study (MOOREA trial) Open
View article: U-Net And Gans-Based PET Synthesis From MRI For Soft-Tissue Sarcomas
U-Net And Gans-Based PET Synthesis From MRI For Soft-Tissue Sarcomas Open
View article: EP1.01-62 The Safety Profile and Preliminary Efficacy of Ceritinib 450mg with Food in Chinese ALK/ROS-1 Positive NSCLC Patients
EP1.01-62 The Safety Profile and Preliminary Efficacy of Ceritinib 450mg with Food in Chinese ALK/ROS-1 Positive NSCLC Patients Open
View article: Graphical Optimization and Inverse Planning Simulated Annealing: A Dosimetric Study for Cervix Brachytherapy Treatments
Graphical Optimization and Inverse Planning Simulated Annealing: A Dosimetric Study for Cervix Brachytherapy Treatments Open
View article: Impact of Positioning Errors on Dose Coverage for Breath-Hold Left-Sided Breast Treatments
Impact of Positioning Errors on Dose Coverage for Breath-Hold Left-Sided Breast Treatments Open
View article: Additional file 1: of Clinicopathologic predictors of metastasis of different regional lymph nodes in patients intraoperatively diagnosed with stage-I non-small cell lung cancer
Additional file 1: of Clinicopathologic predictors of metastasis of different regional lymph nodes in patients intraoperatively diagnosed with stage-I non-small cell lung cancer Open
Support file containing the Age (G), cigarettes (0:negative, 1:positive), Alcohol (0:negative, 1:positive), chronic bronchitis (0:negative, 1:positive), diabetes (0:negative, 1:positive), tumor history (0:negative, 1:positive), tumor famil…