Jingsong Yuan
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View article: Identification of Milankovitch Cycles and Their Sedimentary Responses in Fine-Grained Depositional Strata on the Southwestern Margin of the Songliao Basin
Identification of Milankovitch Cycles and Their Sedimentary Responses in Fine-Grained Depositional Strata on the Southwestern Margin of the Songliao Basin Open
A series of fault depressions developed in the Kailu area on the southwestern margin of the Songliao Basin, where thick lacustrine fine-grained sedimentary rocks were widely deposited during the initial faulting stage in the Early Cretaceo…
View article: Microscopic Pore–Throat Architecture and Fractal Heterogeneity in Tight Sandstone Reservoirs: Insights from the Denglouku Formation, Xujiaweizi Fault Depression
Microscopic Pore–Throat Architecture and Fractal Heterogeneity in Tight Sandstone Reservoirs: Insights from the Denglouku Formation, Xujiaweizi Fault Depression Open
The heterogeneity of the microscopic pore structure in tight sandstone reservoirs is a key factor limiting the efficient development of natural gas. This study focuses on the tight sandstone of the Denglouku Formation in the Lower Cretaceo…
View article: Irreversible Ring-Opening Polymerization: Harnessing the Thermodynamics of Strainless Monomers
Irreversible Ring-Opening Polymerization: Harnessing the Thermodynamics of Strainless Monomers Open
View article: Association between the ratio of high-density lipoprotein cholesterol to apolipoprotein A-I and in-stent neoatherosclerosis: an optical coherence tomography study
Association between the ratio of high-density lipoprotein cholesterol to apolipoprotein A-I and in-stent neoatherosclerosis: an optical coherence tomography study Open
OCT revealed high HAR levels to be negatively correlated with the incidences of ISNA and TCFA in patients with ISR. HAR is a better indicator of ISNA and plaque fragility than HDL-C itself, thus providing a marker and pathway for better pr…
View article: Lithofacies Characteristics of the Lower Cretaceous Qing 1 Member in the Heiyupao Depression, Northern Binbei Area of the Songliao Basin
Lithofacies Characteristics of the Lower Cretaceous Qing 1 Member in the Heiyupao Depression, Northern Binbei Area of the Songliao Basin Open
Strategic breakthroughs have been made in the exploration and evaluation of Gulong shale oil in the Songliao Basin. However, the Heiyupao Depression, located near the Gulong Depression, hosts a thick section of the Qingshankou Formation sh…
View article: Depositional Environment Conditions and Organic Matter Enrichment Mechanism of the First Member of Upper Cretaceous Qingshankou Formation in the Heiyupao Depression, Northern Songliao Basin
Depositional Environment Conditions and Organic Matter Enrichment Mechanism of the First Member of Upper Cretaceous Qingshankou Formation in the Heiyupao Depression, Northern Songliao Basin Open
The first member of the Qingshankou Formation (Qing Member 1) is rich in oil and gas resources and represents the first lacustrine transgression period, during which the lake basin area reached its maximum. This study utilizes major and tr…
View article: Porphyrin-based porous organic polymer for the NIR-enhanced delivery of bupivacaine towards pain management in bacterial infection therapy
Porphyrin-based porous organic polymer for the NIR-enhanced delivery of bupivacaine towards pain management in bacterial infection therapy Open
Antibiotic-free strategies have gained widespread attention in combating bacterial infection-related wound therapy.
View article: Sedimentary Paleoenvironment and Organic Matter Enrichment of the Ying 4 Member in the Southern Shuangcheng Area, Songliao Basin
Sedimentary Paleoenvironment and Organic Matter Enrichment of the Ying 4 Member in the Southern Shuangcheng Area, Songliao Basin Open
Based on organic carbon content measurement, kerogen microscopic examination, and the analysis of source rock maturity and major/trace elements, this study restores the sedimentary paleoenvironment of the Ying 4 Member in the southern Shua…
View article: Relatlimab: a novel drug targeting immune checkpoint LAG-3 in melanoma therapy
Relatlimab: a novel drug targeting immune checkpoint LAG-3 in melanoma therapy Open
Relatlimab is a type of human immunoglobulin G4 monoclonal blocking antibody. It is the world’s first Lymphocyte-Activation Gene-3 (LAG-3) inhibitor and the third immune checkpoint inhibitor with clinical application, following PD-1 and CT…
View article: Bridging host–guest chemistry with molecule chemistry-covalent organic polyrotaxanes (COPRs): from synthesis to inactivation of bacterial pathogens
Bridging host–guest chemistry with molecule chemistry-covalent organic polyrotaxanes (COPRs): from synthesis to inactivation of bacterial pathogens Open
Covalent organic polyrotaxanes (COPRs), have emerged as thriving artificial intelligent materials, amalgamating the rigid molecular chemistry with flexible supramolecular host–guest chemistry, adopting a “couple hardness with softness” str…
View article: Covalent organic polyrotaxanes based on β-cyclodextrin for iodine capture
Covalent organic polyrotaxanes based on β-cyclodextrin for iodine capture Open
Covalent organic polyrotaxanes (COPRs) were concurrently prepared via the integration of dynamic covalent imine-bond formation with supramolecular self-assembly and targeted introduction of β-cyclodextrin into the three-dimensional porous …
View article: A Convex Approximation for a PDE Constrained Fractional Optimization Problem with an Application to Photonic Crystal Design
A Convex Approximation for a PDE Constrained Fractional Optimization Problem with an Application to Photonic Crystal Design Open
Based on a subspace method and a linear approximation method, a convex algorithm is designed to solve a kind of non-convex PDE constrained fractional optimization problem in this paper.This PDE constrained problem is an infinitedimensional…
View article: Near-infrared active ferrocenyl porous organic polymer with photothermal enhanced enzymatic activity for combination antibacterial application
Near-infrared active ferrocenyl porous organic polymer with photothermal enhanced enzymatic activity for combination antibacterial application Open
A low-cost and easily prepared ferrocene-based broad-spectrum antimicrobial agent ( i.e. , FMC-POP) with near-infrared laser-enhanced enzyme activity was prepared in a facile manner for photothermal/enzyme synergetic antibacterial therapy.
View article: DeepVARwT: Deep Learning for a VAR Model with Trend
DeepVARwT: Deep Learning for a VAR Model with Trend Open
The vector autoregressive (VAR) model has been used to describe the dependence within and across multiple time series. This is a model for stationary time series which can be extended to allow the presence of a deterministic trend in each …
View article: DeepVARwT: Deep Learning for a VAR Model with Trend
DeepVARwT: Deep Learning for a VAR Model with Trend Open
The vector autoregressive (VAR) model has been used to describe the dependence within and across multiple time series. This is a model for stationary time series which can be extended to allow the presence of a deterministic trend in each …
View article: Metathesis Cascade-Triggered Depolymerization of Enyne Self-Immolative Polymers
Metathesis Cascade-Triggered Depolymerization of Enyne Self-Immolative Polymers Open
A novel class of enyne self-immolative polymers (SIPs) capable of me-tathesis cascade-triggered depolymerization is reported. Studies on mod-el compounds established 1,6-enyne structures for efficient metathesis cascade reactions. SIPs inc…
View article: Metathesis Cascade-Triggered Depolymerization of Enyne Self-Immolative Polymers
Metathesis Cascade-Triggered Depolymerization of Enyne Self-Immolative Polymers Open
A novel class of enyne self-immolative polymers (SIPs) capable of me-tathesis cascade-triggered depolymerization is reported. Studies on mod-el compounds established 1,6-enyne structures for efficient metathesis cascade reactions. SIPs inc…
View article: Geared Toward Applications: A Perspective on Functional Sequence-Controlled Polymers
Geared Toward Applications: A Perspective on Functional Sequence-Controlled Polymers Open
Sequence-controlled polymers are an emerging class of synthetic polymers with a regulated sequence of monomers. In the past decade, tremendous progress has been made in the synthesis of polymers with the sophisticated sequence control appr…
View article: Antibiotic use in pig farming and its associated factors in L County in Yunnan, China
Antibiotic use in pig farming and its associated factors in L County in Yunnan, China Open
China has a long history of pig rearing, and it currently raises and consumes approximately half of the pigs in the world. Major improvements have been made in pig farming in China in the last four decades with the growing application of n…
View article: Author response for "Antibiotic use in pig farming and its associated factors in L County in Yunnan, China"
Author response for "Antibiotic use in pig farming and its associated factors in L County in Yunnan, China" Open
View article: 4-Hydroxy- <scp>l</scp> -Proline as a General Platform for Stereoregular Aliphatic Polyesters: Controlled Ring-Opening Polymerization, Facile Functionalization, and Site-Specific Bioconjugation
4-Hydroxy- <span>l</span> -Proline as a General Platform for Stereoregular Aliphatic Polyesters: Controlled Ring-Opening Polymerization, Facile Functionalization, and Site-Specific Bioconjugation Open
Open AccessCCS ChemistryRESEARCH ARTICLE1 Oct 20204-Hydroxy-l-Proline as a General Platform for Stereoregular Aliphatic Polyesters: Controlled Ring-Opening Polymerization, Facile Functionalization, and Site-Specific Bioconjugation Jingsong…
View article: 4-Hydroxyproline-Derived Sustainable Polythioesters: Controlled Ring-Opening Polymerization, Complete Recyclability, and Facile Functionalization
4-Hydroxyproline-Derived Sustainable Polythioesters: Controlled Ring-Opening Polymerization, Complete Recyclability, and Facile Functionalization Open
The sustainable production of chemically recyclable polymers presents a significant opportunity to polymer scientists to tackle the growing environmental and energy problems of current petroleum-based plastics. Despite recent advances, how…
View article: Therapeutic Protein PEPylation: The Helix of Nonfouling Synthetic Polypeptides Minimizes Antidrug Antibody Generation
Therapeutic Protein PEPylation: The Helix of Nonfouling Synthetic Polypeptides Minimizes Antidrug Antibody Generation Open
Polymer conjugation is a clinically proven approach to generate long acting protein drugs with decreased immune responses. Although poly(ethylene glycol) (PEG) is one of the most commonly used conjugation partners due to its unstructured c…
View article: CCDC 1906013: Experimental Crystal Structure Determination
CCDC 1906013: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1906012: Experimental Crystal Structure Determination
CCDC 1906012: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Mitosis-specific MRN complex promotes a mitotic signaling cascade to regulate spindle dynamics and chromosome segregation
Mitosis-specific MRN complex promotes a mitotic signaling cascade to regulate spindle dynamics and chromosome segregation Open
Significance The Mre11–Rad50–Nbs1 (MRN) complex is well known for participating in DNA damage response pathways and mediating the ATM-dependent phosphorylation signaling cascade. Hypomorphic mutations in the human MRN complex have been ide…
View article: RNF169 limits 53BP1 deposition at DSBs to stimulate single-strand annealing repair
RNF169 limits 53BP1 deposition at DSBs to stimulate single-strand annealing repair Open
Significance 53BP1 restrains DNA end resection, and its dosage imbalance upsets DNA double-strand break (DSB) repair pathway choice. Here, by monitoring 53BP1 distribution on DSB-flanking chromatin, we have established a dose-dependent rol…
View article: Transitional basal cells at the squamous–columnar junction generate Barrett’s oesophagus
Transitional basal cells at the squamous–columnar junction generate Barrett’s oesophagus Open
View article: Clustered, Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9-coupled Affinity Purification/Mass Spectrometry Analysis Revealed a Novel Role of Neurofibromin in mTOR Signaling
Clustered, Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9-coupled Affinity Purification/Mass Spectrometry Analysis Revealed a Novel Role of Neurofibromin in mTOR Signaling Open
View article: RPA-Binding Protein ETAA1 Is an ATR Activator Involved in DNA Replication Stress Response
RPA-Binding Protein ETAA1 Is an ATR Activator Involved in DNA Replication Stress Response Open