Jia Song
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View article: Machine Learning-Based Models for the Prediction of Postoperative Recurrence Risk in MVI-Negative HCC
Machine Learning-Based Models for the Prediction of Postoperative Recurrence Risk in MVI-Negative HCC Open
Background: Hepatocellular carcinoma (HCC) patients without microvascular invasion (MVI) face significant postoperative early recurrence (ER) risks, yet prognostic determinants remain understudied. Existing models often rely on linear assu…
View article: Lipid metabolic reprogramming in colorectal cancer: Insights to mechanisms and therapeutics
Lipid metabolic reprogramming in colorectal cancer: Insights to mechanisms and therapeutics Open
Colorectal cancer (CRC) exhibits profound lipid metabolic reprogramming, a hallmark of malignant transformation that supports tumorigenesis, immune evasion, and therapeutic resistance. Dysregulated lipid metabolism in CRC involves altered …
View article: The effect and mechanism of human amniotic mesenchymal stem cells on scar formation in rat uterine incision
The effect and mechanism of human amniotic mesenchymal stem cells on scar formation in rat uterine incision Open
Cesarean section (CS) scar tissue fibrosis and decreased muscle density increase the risk of uterine rupture and placental implantation in subsequent pregnancies. Given the potent anti-fibrotic and regenerative properties of human amniotic…
View article: Using An Autonomous Robot-Assisted Autogenous Tooth Transplantation
Using An Autonomous Robot-Assisted Autogenous Tooth Transplantation Open
Introduction: Autogenous tooth transplantation is a restorative technique that involves transplanting a patient's own tooth into an edentulous area, typically using a third molar to replace a nonfunctional molar, thereby ''repurposing a di…
View article: Robot-assisted autotransplantation of third molars in the maxilla: two case reports
Robot-assisted autotransplantation of third molars in the maxilla: two case reports Open
Autotransplantation of teeth has attracted increasing attention due to its excellent biocompatibility and ability to preserve natural dentition. However, conventional autotransplantation of tooth techniques are highly technique-sensitive a…
View article: Tubular epithelial cell-derived extracellular vesicles carrying serum amyloid A1 exacerbate sepsis-associated acute kidney injury by promoting NETs formation
Tubular epithelial cell-derived extracellular vesicles carrying serum amyloid A1 exacerbate sepsis-associated acute kidney injury by promoting NETs formation Open
Introduction Sepsis-associated acute kidney injury (SA-AKI) is a highly lethal condition with a rapid onset, and effective treatments are lacking because the molecular pathogenesis remains unclear. Tubular epithelial cells (TECs) have incr…
View article: A Blended Teaching Model for College English Teaching Based on the Production-Oriented Approach
A Blended Teaching Model for College English Teaching Based on the Production-Oriented Approach Open
Social development puts forward higher requirements for students’ English application ability and cultural literacy. This study proposes an innovative “3+2+1” blended teaching model integrating the production-oriented approach (POA) to add…
View article: Lipid Profiling of Four Guava Cultivars: A Multi-Dimensional Spatial Analysis
Lipid Profiling of Four Guava Cultivars: A Multi-Dimensional Spatial Analysis Open
This study aimed to reveal the lipid composition and distribution and characterize the lipid metabolism profile in the three distinct parts of four guava varieties with varying textures and colors using liquid chromatography–electrospray i…
View article: Dynamic deployment of H2A.Z positive nucleosome mediated transcriptomic plasticity within vascular smooth muscle cell
Dynamic deployment of H2A.Z positive nucleosome mediated transcriptomic plasticity within vascular smooth muscle cell Open
Vascular SMCs dynamically deployed H2A.Z-positive nucleosomes extending continuously downstream transcription start sites on different genes to support their transcriptional adjustability, which served as an important mechanism mediating c…
View article: Research on the multiscale mechanical properties of paleosols based on the freeze‒thaw cycle
Research on the multiscale mechanical properties of paleosols based on the freeze‒thaw cycle Open
To study the failure mechanism of paleosol landslides, taking the paleosol of a landslide body in Yan'an as an example, scanning electron microscopy (SEM), nuclear magnetic resonance (NMR), and conventional triaxial tests were used to obta…
View article: Understanding teachers’ enactment of assessment for learning: A theoretical framework
Understanding teachers’ enactment of assessment for learning: A theoretical framework Open
Assessment for learning has received extensive interest in assessment research and practice. However, despite the research on teachers’ assessment for learning practices, there has been limited attention paid to understanding and theorisin…
View article: Protein serine/threonine phosphatases in tumor microenvironment: a vital player and a promising therapeutic target
Protein serine/threonine phosphatases in tumor microenvironment: a vital player and a promising therapeutic target Open
The tumor microenvironment (TME) is involved in cancer initiation and progression. With advances in the TME field, numerous therapeutic approaches, such as antiangiogenic treatment and immune checkpoint inhibitors, have been inspired and d…
View article: Pre-pregnancy fertility guidance for women of childbearing age with epilepsy: A scoping review
Pre-pregnancy fertility guidance for women of childbearing age with epilepsy: A scoping review Open
We have synthesized the most compelling evidence regarding reproductive counseling for women with epilepsy across the preconception, pregnancy, labor and delivery, and postpartum periods. This serves as a foundation for healthcare professi…
View article: Tailoring cell therapies for diabetic metabolic phenotypes: a comparative study on the efficacy of various umbilical cord-derived cell regimens
Tailoring cell therapies for diabetic metabolic phenotypes: a comparative study on the efficacy of various umbilical cord-derived cell regimens Open
Given the high heterogeneity of type 2 diabetes mellitus (T2DM), it is imperative to develop personalized stem cell infusion regimen for targeted metabolic phenotype in order to ensure optimal therapeutic efficacy. In this study, we conduc…
View article: N6-methyladenosine modification of circular RNA circASH2L suppresses growth and metastasis in hepatocellular carcinoma through regulating hsa-miR-525-3p/MTUS2 axis
N6-methyladenosine modification of circular RNA circASH2L suppresses growth and metastasis in hepatocellular carcinoma through regulating hsa-miR-525-3p/MTUS2 axis Open
The work emphasizes circASH2L as a promising therapeutic target for treating HCC, offering new insights into the role of circRNAs in HCC development.
View article: Teachers’ Interaction with Prescribed Teaching Materials: Evaluation, Adaptation and Exploitation
Teachers’ Interaction with Prescribed Teaching Materials: Evaluation, Adaptation and Exploitation Open
In recent years, material development in English language teaching has received growing attention, yet the interaction between English language teachers and prescribed teaching materials remains an under-researched area. This study aims to…
View article: N6-methyladenosine modification of circular RNA circASH2L suppresses growth and metastasis in hepatocellular carcinoma through regulating hsa-miR-525-3p/MTUS2 axis
N6-methyladenosine modification of circular RNA circASH2L suppresses growth and metastasis in hepatocellular carcinoma through regulating hsa-miR-525-3p/MTUS2 axis Open
Background CircRNAs have been demonstrated to play a crucial role in regulating the growth and progression of various cancers, including hepatocellular carcinoma (HCC). Nevertheless, the circRNA's expression pattern and function in HCC nee…
View article: Knockdown of HSPA13 Inhibits TGFβ1-Induced Epithelial-Mesenchymal Transition of RPE by Suppressing the PI3K/Akt Signaling Pathway
Knockdown of HSPA13 Inhibits TGFβ1-Induced Epithelial-Mesenchymal Transition of RPE by Suppressing the PI3K/Akt Signaling Pathway Open
Our study revealed the involvement of HSPA13 in PVR development, as well as in TGFβ1-induced EMT of RPE through the PI3K/Akt signaling pathway. Targeting HSPA13-related pathways involved in regulating EMT in RPE cells could serve as a nove…
View article: Residual attention based multi-label learning for apple leaf disease identification
Residual attention based multi-label learning for apple leaf disease identification Open
Recent studies suggest that plant disease identification via machine learning approach is vital for preventing the spread of diseases. Identifying multiple diseases simultaneous on a single leaf is one of the most irritating issues in agri…
View article: Effective Teaching and Learning: Characteristics and Practices of People-oriented in International Chinese Language Education
Effective Teaching and Learning: Characteristics and Practices of People-oriented in International Chinese Language Education Open
School education plays a crucial role in the process of cultivating innovative talents, and the direct target of teaching is students. At present, the aim of education and teaching is to adhere to the concept of human-centered teaching and…
View article: Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues Open
Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricul…
View article: ACT001 inhibits primary central nervous system lymphoma tumor growth by enhancing the anti-tumor effect of T cells
ACT001 inhibits primary central nervous system lymphoma tumor growth by enhancing the anti-tumor effect of T cells Open
Primary central nervous system lymphoma (PCNSL) is a group of malignant brain tumors with a poor prognosis, and new therapeutic approaches for this tumor urgently need to be investigated. Formulated from a long-standing anti-inflammatory d…
View article: Study of Factors Influencing the Oral Bioaccessibility of Commonly Used and Detected Pesticides in Bananas and Mangoes Based on in vitro Methods
Study of Factors Influencing the Oral Bioaccessibility of Commonly Used and Detected Pesticides in Bananas and Mangoes Based on in vitro Methods Open
Estimating the impact of pesticide residue bioaccessibility in fruits on dietary exposure is a complex task in human health risk assessment. This research investigated the bioaccessibility of ten commonly used and detected pesticides in ba…
View article: Perforation and surgical prognosis of acute appendicitis, and a prediction nomogram for perforated appendicitis in adults: a retrospective study
Perforation and surgical prognosis of acute appendicitis, and a prediction nomogram for perforated appendicitis in adults: a retrospective study Open
Background The safety and feasibility of performing appendectomy beyond the initial 72-hour period following symptom onset remain largely unknown. Aims This retrospective study aims to provide valuable insights for the prospective clinical…