Jingzhun Liu
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View article: The mechanical response of vinculin
The mechanical response of vinculin Open
Vinculin is a mechanosensitive adaptor that links actin to cell-matrix and cell-cell adhesions. Known as a mechanoeffector, it is recruited to adhesion sites under force via mechanotransducers talin and α-catenin. Here, we examine vinculin…
View article: Alternative molecular mechanisms for force transmission at adherens junctions via β-catenin-vinculin interaction
Alternative molecular mechanisms for force transmission at adherens junctions via β-catenin-vinculin interaction Open
View article: Unraveling the Dual-Mode Impact on Tension Gauge Tethers’ Mechanical Stability
Unraveling the Dual-Mode Impact on Tension Gauge Tethers’ Mechanical Stability Open
Tension Gauge Tethers (TGTs), short DNA segments serving as extracellular tension sensors, are instrumental in assessing tension dynamics in mechanotransduction. These TGTs feature an initial shear-stretch region and an unzip-stretch regio…
View article: The mechanical stability of Tension Gauge Tethers
The mechanical stability of Tension Gauge Tethers Open
Mechanotransduction of cells relies on responding to tension transmitted along various supramolecular linkages. Tension gauge tethers (TGTs), short double-stranded DNA (dsDNA) fragments that undergo irreversible tension-dependent dissociat…