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View article: Human Nervous System‐Based Biohybrid Robot‐On‐A‐Chip with Sensing Function for Toxicity Screening
Human Nervous System‐Based Biohybrid Robot‐On‐A‐Chip with Sensing Function for Toxicity Screening Open
Biohybrid robots and biohybrid robot‐on‐a‐chip have been developed for drug screening and toxicity screening the complementing animal experiments. A sensing system is needed to evaluate the response to external stimulation, but until now, …
View article: CRISPR/Cas-Based Nanobiosensor Using Plasmonic Nanomaterials to Detect Disease Biomarkers
CRISPR/Cas-Based Nanobiosensor Using Plasmonic Nanomaterials to Detect Disease Biomarkers Open
The development of clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated protein (Cas) technology (CRISPR/Cas) as a gene-editing tool has the potential to revolutionize nucleic acid analysis. Recently, CR…
View article: Electrochemical Biosensor for Multiplexed Detection of Nucleic Acid Using DNA Three-Way Junction with Metal Ion Intercalation
Electrochemical Biosensor for Multiplexed Detection of Nucleic Acid Using DNA Three-Way Junction with Metal Ion Intercalation Open
View article: Flexible Electrochemical Biosensor Using Nanostructure-Modified Polymer Electrode for Detection of Viral Nucleic Acids
Flexible Electrochemical Biosensor Using Nanostructure-Modified Polymer Electrode for Detection of Viral Nucleic Acids Open
In the biosensor field, the accurate detection of contagious disease has become one of the most important research topics in the post-pandemic period. However, conventional contagious viral biosensors normally require chemical modification…
View article: Carbon-based nanocomposites for biomedical applications
Carbon-based nanocomposites for biomedical applications Open
In this review, we discussed the unique features of carbon nanomaterial-integrated nanocomposites for application in the biomedical field, including for biosensors, drug delivery, and tissue engineering.
View article: Human Motor System‐Based Biohybrid Robot‐On‐a‐Chip for Drug Evaluation of Neurodegenerative Disease
Human Motor System‐Based Biohybrid Robot‐On‐a‐Chip for Drug Evaluation of Neurodegenerative Disease Open
Biohybrid robots have been developed for biomedical applications and industrial robotics. However, the biohybrid robots have limitations to be applied in neurodegenerative disease research due to the absence of a central nervous system. In…
View article: An Updated Review on Electrochemical Nanobiosensors for Neurotransmitter Detection
An Updated Review on Electrochemical Nanobiosensors for Neurotransmitter Detection Open
Neurotransmitters are chemical compounds released by nerve cells, including neurons, astrocytes, and oligodendrocytes, that play an essential role in the transmission of signals in living organisms, particularly in the central nervous syst…
View article: Enzymatic Electrochemical/Fluorescent Nanobiosensor for Detection of Small Chemicals
Enzymatic Electrochemical/Fluorescent Nanobiosensor for Detection of Small Chemicals Open
The detection of small molecules has attracted enormous interest in various fields, including the chemical, biological, and healthcare fields. In order to achieve such detection with high accuracy, up to now, various types of biosensors ha…
View article: Nanomaterial-based biohybrid hydrogel in bioelectronics
Nanomaterial-based biohybrid hydrogel in bioelectronics Open
View article: Nanotechnology-Assisted Biosensors for the Detection of Viral Nucleic Acids: An Overview
Nanotechnology-Assisted Biosensors for the Detection of Viral Nucleic Acids: An Overview Open
The accurate and rapid diagnosis of viral diseases has garnered increasing attention in the field of biosensors. The development of highly sensitive, selective, and accessible biosensors is crucial for early disease detection and preventin…
View article: Recent Developments in DNA-Nanotechnology-Powered Biosensors for Zika/Dengue Virus Molecular Diagnostics
Recent Developments in DNA-Nanotechnology-Powered Biosensors for Zika/Dengue Virus Molecular Diagnostics Open
Zika virus (ZIKV) and dengue virus (DENV) are highly contagious and lethal mosquito-borne viruses. Global warming is steadily increasing the probability of ZIKV and DENV infection, and accurate diagnosis is required to control viral infect…
View article: Acoustic force spectroscopy reveals subtle differences in cellulose unbinding behavior of carbohydrate-binding modules
Acoustic force spectroscopy reveals subtle differences in cellulose unbinding behavior of carbohydrate-binding modules Open
Protein adsorption to solid carbohydrate interfaces is critical to many biological processes, particularly in biomass deconstruction. To engineer more-efficient enzymes for biomass deconstruction into sugars, it is necessary to characteriz…
View article: Receptor‐Level Proximity and Fastening of Ligands Modulates Stem Cell Differentiation (Adv. Funct. Mater. 30/2022)
Receptor‐Level Proximity and Fastening of Ligands Modulates Stem Cell Differentiation (Adv. Funct. Mater. 30/2022) Open
Integrin Clustering In article number 2200828, Young Keun Kim, Heemin Kang, and co-workers report the dynamic tuning of receptor-level ligand proximity. Closely spaced ligands coated onto subordinate nanostructures distributed on a nano-te…
View article: High-Content Screening and Analysis of Stem Cell-Derived Neural Interfaces Using a Combinatorial Nanotechnology and Machine Learning Approach
High-Content Screening and Analysis of Stem Cell-Derived Neural Interfaces Using a Combinatorial Nanotechnology and Machine Learning Approach Open
A systematic investigation of stem cell-derived neural interfaces can facilitate the discovery of the molecular mechanisms behind cell behavior in neurological disorders and accelerate the development of stem cell-based therapies. Neverthe…
View article: Fabrication of MERS-nanovesicle biosensor composed of multi-functional DNA aptamer/graphene-MoS2 nanocomposite based on electrochemical and surface-enhanced Raman spectroscopy
Fabrication of MERS-nanovesicle biosensor composed of multi-functional DNA aptamer/graphene-MoS2 nanocomposite based on electrochemical and surface-enhanced Raman spectroscopy Open
View article: Acoustic Force Spectroscopy Reveals Subtle Differences in Cellulose Unbinding Behavior of Carbohydrate-Binding Modules
Acoustic Force Spectroscopy Reveals Subtle Differences in Cellulose Unbinding Behavior of Carbohydrate-Binding Modules Open
To rationally engineer more efficient cellulolytic enzymes for cellulosic biomass deconstruction into sugars for biofuels production, it is necessary to better understand the complex enzyme-substrate interfacial interactions. Carbohydrate …
View article: Electrochemical Cell Chips Based on Functionalized Nanometals
Electrochemical Cell Chips Based on Functionalized Nanometals Open
The electrochemical technique is one of the most accurate, rapid, and sensitive analytical assays, which becomes promising techniques for biological assays at a single-cell scale. Nanometals have been widely used for modification of the tr…
View article: Graphene/MoS2 Nanohybrid for Biosensors
Graphene/MoS2 Nanohybrid for Biosensors Open
Graphene has been studied a lot in different scientific fields because of its unique properties, including its superior conductivity, plasmonic property, and biocompatibility. More recently, transition metal dicharcogenide (TMD) nanomateri…
View article: Recent Advances in MXene Nanocomposite-Based Biosensors
Recent Advances in MXene Nanocomposite-Based Biosensors Open
The development of advanced biosensors with high sensitivity and selectivity is one of the most demanded concerns in the field of biosensors. To meet this requirement, up until now, numerous nanomaterials have been introduced to develop bi…
View article: Recent Advances in Biomolecule–Nanomaterial Heterolayer-Based Charge Storage Devices for Bioelectronic Applications
Recent Advances in Biomolecule–Nanomaterial Heterolayer-Based Charge Storage Devices for Bioelectronic Applications Open
With the acceleration of the Fourth Industrial Revolution, the development of information and communications technology requires innovative information storage devices and processing devices with low power and ultrahigh stability. Accordin…
View article: MicroRNA Detection: Single Functionalized pRNA/Gold Nanoparticle for Ultrasensitive MicroRNA Detection Using Electrochemical Surface‐Enhanced Raman Spectroscopy (Adv. Sci. 3/2020)
MicroRNA Detection: Single Functionalized pRNA/Gold Nanoparticle for Ultrasensitive MicroRNA Detection Using Electrochemical Surface‐Enhanced Raman Spectroscopy (Adv. Sci. 3/2020) Open
In article number https://doi.org/10.1002/advs.201902477, Peixuan Guo, Jeong‐Woo Choi, and co‐workers fabricate monofunctionalized gold nanoparticles (AuNPs) with a single copy of an RNA three‐way junction (3WJ) motif for application in ul…
View article: Highly Sensitive Biosensors Based on Biomolecules and Functional Nanomaterials Depending on the Types of Nanomaterials: A Perspective Review
Highly Sensitive Biosensors Based on Biomolecules and Functional Nanomaterials Depending on the Types of Nanomaterials: A Perspective Review Open
Biosensors are very important for detecting target molecules with high accuracy, selectivity, and signal-to-noise ratio. Biosensors developed using biomolecules such as enzymes or nucleic acids which were used as the probes for detecting t…
View article: Single Functionalized pRNA/Gold Nanoparticle for Ultrasensitive MicroRNA Detection Using Electrochemical Surface‐Enhanced Raman Spectroscopy
Single Functionalized pRNA/Gold Nanoparticle for Ultrasensitive MicroRNA Detection Using Electrochemical Surface‐Enhanced Raman Spectroscopy Open
Controlling the selective one‐to‐one conjugation of RNA with nanoparticles is vital for future applications of RNA nanotechnology. Here, the monofunctionalization of a gold nanoparticle (AuNP) with a single copy of RNA is developed for ult…
View article: Flexible HIV-1 Biosensor Based on the Au/MoS2 Nanoparticles/Au Nanolayer on the PET Substrate
Flexible HIV-1 Biosensor Based on the Au/MoS2 Nanoparticles/Au Nanolayer on the PET Substrate Open
An electrochemical flexible biosensor composed of gold (Au), molybdenum disulfide nanoparticles (MoS2 NPs), and Au (Au/MoS2/Au nanolayer) on the polyethylene terephthalate (PET) substrate is developed to detect envelope glycoprotein GP120 …
View article: Fabrication of Troponin I Biosensor Composed of Multi-Functional DNA Structure/Au Nanocrystal Using Electrochemical and Localized Surface Plasmon Resonance Dual-Detection Method
Fabrication of Troponin I Biosensor Composed of Multi-Functional DNA Structure/Au Nanocrystal Using Electrochemical and Localized Surface Plasmon Resonance Dual-Detection Method Open
In the present study, we fabricated a dual-mode cardiac troponin I (cTnI) biosensor comprised of multi-functional DNA (MF-DNA) on Au nanocrystal (AuNC) using an electrochemical method (EC) and a localized surface plasmon resonance (LSPR) m…
View article: Development of Bioelectronic Devices Using Bionanohybrid Materials for Biocomputation System
Development of Bioelectronic Devices Using Bionanohybrid Materials for Biocomputation System Open
Bioelectronic devices have been researched widely because of their potential applications, such as information storage devices, biosensors, diagnosis systems, organism-mimicking processing system cell chips, and neural-mimicking systems. I…
View article: H2O2 biosensor consisted of hemoglobin-DNA conjugate on nanoporous gold thin film electrode with electrochemical signal enhancement
H2O2 biosensor consisted of hemoglobin-DNA conjugate on nanoporous gold thin film electrode with electrochemical signal enhancement Open
In this research, we developed electrochemical biosensor which was composed of hemoglobin (Hb)-DNA conjugate on nanoporous gold thin film (NPGF) for hydrogen peroxide (H2O2) detection. For the first time, Hb and DNA w…
View article: Nanostructured surfaces for analysis of anticancer drug and cell diagnosis based on electrochemical and SERS tools
Nanostructured surfaces for analysis of anticancer drug and cell diagnosis based on electrochemical and SERS tools Open
View article: Silver Nanoparticle Modified Electrode Covered by Graphene Oxide for the Enhanced Electrochemical Detection of Dopamine
Silver Nanoparticle Modified Electrode Covered by Graphene Oxide for the Enhanced Electrochemical Detection of Dopamine Open
Several neurological disorders such as Alzheimer’s disease and Parkinson’s disease have become a serious impediment to aging people nowadays. One of the efficient methods used to monitor these neurological disorders is the detection of neu…
View article: Investigation of Hemoglobin/Gold Nanoparticle Heterolayer on Micro-Gap for Electrochemical Biosensor Application
Investigation of Hemoglobin/Gold Nanoparticle Heterolayer on Micro-Gap for Electrochemical Biosensor Application Open
In the present study, we fabricated a hemoglobin/gold nanoparticle (Hb/GNP) heterolayer immobilized on the Au micro-gap to confirm H2O2 detection with a signal-enhancement effect. The hemoglobin which contained the heme group catalyzed the…