Jinjing Zhang
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View article: Oral Vaccination with Aeromonas veronii Ghost Against Lethal Bacterial Infection in Cyprinus carpio
Oral Vaccination with Aeromonas veronii Ghost Against Lethal Bacterial Infection in Cyprinus carpio Open
Background/Objectives: Aeromonas veronii is a significant pathogen affecting aquatic animals and has the potential to infect humans. Vaccination remains the most effective strategy for preventing infections caused by this bacterial strain.…
View article: Type-I interferon priming signal balances anti-bacterial and anti-tumor trained immunity in alveolar macrophages
Type-I interferon priming signal balances anti-bacterial and anti-tumor trained immunity in alveolar macrophages Open
Tissue-resident macrophages may be trained to confer enhanced response to heterologous re-stimulation, and thus foster versatile trained immunity (TI) against both infections and tumors. However, key priming signals that contribute to such…
View article: Fat-rich diet reprograms intrapulmonary neutrophils to boost tissue-specific antitumor immunity
Fat-rich diet reprograms intrapulmonary neutrophils to boost tissue-specific antitumor immunity Open
Neutrophils adapt to tissue-specific signals and exert innate defense functions against infections and malignancies. Fat-rich diet (FRD), such as high-fat diet (HFD) and ketogenic diet (KD), has complex impacts on immunity. However, whethe…
View article: The Effects of Fishmeal Replacement with Degossypolled Cottonseed Protein on Growth, Serum Biochemistry, Endocrine Responses, Lipid Metabolism, and Antioxidant and Immune Responses in Black Carp (Mylopharyngodon piceus)
The Effects of Fishmeal Replacement with Degossypolled Cottonseed Protein on Growth, Serum Biochemistry, Endocrine Responses, Lipid Metabolism, and Antioxidant and Immune Responses in Black Carp (Mylopharyngodon piceus) Open
This research investigated the growth, serum biochemistry, antioxidant capability, and immunity impact of black carp fed degossypolled cottonseed protein replacing fishmeal at the levels of 0%, 10%, 20%, 30%, 40%, and 50% (DCP0, DCP10, DCP…
View article: Germline mutations predispose a concurrent thymoma and diffuse large B-cell lymphoma
Germline mutations predispose a concurrent thymoma and diffuse large B-cell lymphoma Open
View article: Bacterial pneumonia induces senescence in resident alveolar macrophages that are outcompeted by monocytes
Bacterial pneumonia induces senescence in resident alveolar macrophages that are outcompeted by monocytes Open
View article: Multi-targeted nanogel drug delivery system alleviates neuroinflammation and promotes spinal cord injury repair
Multi-targeted nanogel drug delivery system alleviates neuroinflammation and promotes spinal cord injury repair Open
View article: OTUD7B is a new deubiquitinase targeting p53
OTUD7B is a new deubiquitinase targeting p53 Open
Rationale: The tumor suppressor p53 safeguards against cellular transformation, with its expression regulated by diverse post-translational modifications (PTMs). While polyubiquitination by Mdm2 principally drives its proteasomal de…
View article: Electric field-assisted annular arrangement of sulfonated polystyrene particles for isotropically enhanced matrix performance
Electric field-assisted annular arrangement of sulfonated polystyrene particles for isotropically enhanced matrix performance Open
An ordered and rationally designed distribution structure can fully exploit the superior properties of micro/nano-fillers, maximizing the synergistic effects between the fillers and the matrix.
View article: Meta-Skin-Based Ultrasonic Instrument Enabling Highly Selective Ultrasound Stimulation and Treatment
Meta-Skin-Based Ultrasonic Instrument Enabling Highly Selective Ultrasound Stimulation and Treatment Open
The rapid development of metasurface has produced new possibilities for manipulating the sound waves with unprecedented precision and versatility. Leveraging advanced processing techniques such as 3-dimensional (3D) printing and nano-/micr…
View article: Photothermal-enhanced silver nanocluster bioactive glass hydrogels for synergistic antimicrobial and promote wound healing
Photothermal-enhanced silver nanocluster bioactive glass hydrogels for synergistic antimicrobial and promote wound healing Open
Antibacterial hydrogels are promising for combating infections and promoting wound healing. Nevertheless, excessive antibiotics induce resistance, and high metal ion levels cause cytotoxicity, complicating healing. Here, we introduce a hyd…
View article: A survey in Liangshan, Sichuan showed higher human papillomavirus infection rate and cervical cancer risk for Yi Chinese compared to Han Chinese
A survey in Liangshan, Sichuan showed higher human papillomavirus infection rate and cervical cancer risk for Yi Chinese compared to Han Chinese Open
Background: Human papillomavirus (HPV) is a sexually transmitted virus reported to be strongly correlated to the development of cervical cancers. An ethnic minority in Liangshan, Sichuan known as Yi Chinese were reported to be more suscept…
View article: RFLSE: Joint radiomics feature‐enhanced level‐set segmentation for low‐contrast SPECT/CT tumour images
RFLSE: Joint radiomics feature‐enhanced level‐set segmentation for low‐contrast SPECT/CT tumour images Open
Doctors typically use non‐contrast‐enhanced computed tomography (NCECT) in the treatment of kidney cancer to map kidney and tumour structural information to functional imaging single‐photon emission computed tomography, which is then used …
View article: Megalosplenia as an initial manifestation of multiple myeloma with a novel CYLD gene mutation: A case report and literature review
Megalosplenia as an initial manifestation of multiple myeloma with a novel CYLD gene mutation: A case report and literature review Open
Introduction: Megalosplenia in newly diagnosed multiple myeloma (MM) is extremely rare, posing diagnostic and therapeutic challenges due to its unusual location and clinical manifestations and lack of optimal therapeutic strategies. Case p…
View article: Comparative Transcriptome Profiles of the Response of Mycelia of the Genus Morchella to Temperature Stress: An Examination of Potential Resistance Mechanisms
Comparative Transcriptome Profiles of the Response of Mycelia of the Genus Morchella to Temperature Stress: An Examination of Potential Resistance Mechanisms Open
Temperature and moisture belong to the most important environmental factors affecting the growth and development of fungi. However, the effect of temperature on the mycelia of the edible Morchella mushrooms has not been determined. Here, a…
View article: Acupuncture for cervical dystonia associated with anxiety and depression: A case report
Acupuncture for cervical dystonia associated with anxiety and depression: A case report Open
BACKGROUND Cervical dystonia (CD) is a type of muscle tone disorder that usually occurs in the neck muscles. Due to the intermittent or continuous involuntary contraction of the neck muscles, the head and neck are twisted and skewed and so…
View article: Case Report: CD19 CAR T-cell therapy following autologous stem cell transplantation: a successful treatment for R/R CD20-negative transformed follicular lymphoma with TP53 mutation
Case Report: CD19 CAR T-cell therapy following autologous stem cell transplantation: a successful treatment for R/R CD20-negative transformed follicular lymphoma with TP53 mutation Open
Background Follicular lymphoma (FL), a common indolent B-cell lymphoma, has the potential to transform into an aggressive lymphoma, such as diffuse large B-cell lymphoma (DLBCL). The outcome of patients with transformed follicular lymphoma…
View article: Effect of Sleep Quality on Anxiety and Depression Symptoms among College Students in China’s Xizang Region: The Mediating Effect of Cognitive Emotion Regulation
Effect of Sleep Quality on Anxiety and Depression Symptoms among College Students in China’s Xizang Region: The Mediating Effect of Cognitive Emotion Regulation Open
Background: While the exact mechanisms are not fully understood, there are significant links between sleep quality, anxiety, depressive symptoms, and cognitive emotion regulation. This research examines how sleep quality affects anxiety an…
View article: Dynamic alterations of the transcriptome-wide m6A methylome in cytogenetically normal acute myeloid leukaemia during initial diagnosis and relapse
Dynamic alterations of the transcriptome-wide m6A methylome in cytogenetically normal acute myeloid leukaemia during initial diagnosis and relapse Open
Accumulating studies have indicated that N6-methyladenosine (m6A) plays an important role in acute myeloid leukaemia (AML). However, little is known about the m6A methylome at a transcriptome-wide scale in AML patient…
View article: Prevalence, drug resistance, molecular typing and comparative genomics analysis of MRSA strains from a tertiary A hospital in Shanxi Province, China
Prevalence, drug resistance, molecular typing and comparative genomics analysis of MRSA strains from a tertiary A hospital in Shanxi Province, China Open
Staphylococcus aureus ( S. aureus ) is an important zoonotic pathogen that causes a high incidence rate and mortality worldwide. This study investigated the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) strains in a tert…
View article: Effects of Different Nitrogen Levels on Lignocellulolytic Enzyme Production and Gene Expression under Straw-State Cultivation in Stropharia rugosoannulata
Effects of Different Nitrogen Levels on Lignocellulolytic Enzyme Production and Gene Expression under Straw-State Cultivation in Stropharia rugosoannulata Open
Stropharia rugosoannulata has been used in environmental engineering to degrade straw in China. The nitrogen and carbon metabolisms are the most important factors affecting mushroom growth, and the aim of this study was to understand the e…
View article: Antibiotic susceptibility of Escherichia coli isolated from neonates admitted to neonatal intensive care units across China from 2015 to 2020
Antibiotic susceptibility of Escherichia coli isolated from neonates admitted to neonatal intensive care units across China from 2015 to 2020 Open
Background Escherichia coli is one of the most common pathogens causing neonatal infections. Recently, the incidence and drug resistance of E. coli have increased, posing a major threat to neonatal health. The aim of this study was to desc…
View article: Lipopolysaccharide downregulates the expression of ZO-1 protein through the Akt pathway
Lipopolysaccharide downregulates the expression of ZO-1 protein through the Akt pathway Open
Background Neonatal bacterial meningitis is a common neonatal disease with high morbidity, and can cause serious sequelae when left untreated. Escherichia coli is the common pathogen, and its endotoxin, lipopolysaccharide (LPS) can damage …
View article: The neuropeptide Y single-nucleotide polymorphism rs16147:T>C moderates the effect of alcohol dependence on depression in male Chinese Han population
The neuropeptide Y single-nucleotide polymorphism rs16147:T>C moderates the effect of alcohol dependence on depression in male Chinese Han population Open
Background Previous studies suggest that alcohol dependence is associated with depression, however, the effect of alcohol dependence varies from individual to individual, which may be due to different genetic backgrounds. The interactions …
View article: Lactobacillus plantarum ST-III culture supernatant ameliorates alcohol-induced cognitive dysfunction by reducing endoplasmic reticulum stress and oxidative stress
Lactobacillus plantarum ST-III culture supernatant ameliorates alcohol-induced cognitive dysfunction by reducing endoplasmic reticulum stress and oxidative stress Open
Background Long-term alcohol exposure is associated with oxidative stress, endoplasmic reticulum (ER) stress, and neuroinflammation, which may impair cognitive function. Probiotics supplements can significantly improve cognitive function i…
View article: Trends of Tourette Syndrome in children From 2011 to 2021: A Bibliometric Analysis
Trends of Tourette Syndrome in children From 2011 to 2021: A Bibliometric Analysis Open
Background Tourette Syndrome (TS) has attracted the attention of researchers worldwide. However, no bibliometric analysis of the published publications is available. This study aims to examine the present research state of TS in children b…
View article: Bilateral diffuse uveal melanocytic proliferation associated with endometrial carcinoma – multimodal imaging analysis
Bilateral diffuse uveal melanocytic proliferation associated with endometrial carcinoma – multimodal imaging analysis Open
View article: Transcriptome and Differentially Expressed Gene Profiles in Mycelium, Primordium and Fruiting Body Development in Stropharia rugosoannulata
Transcriptome and Differentially Expressed Gene Profiles in Mycelium, Primordium and Fruiting Body Development in Stropharia rugosoannulata Open
Stropharia rugosoannulata uses straw as a growth substrate during artificial cultivation and has been widely promoted in China. However, its fruiting body formation and development processes have not been elucidated. In this study, the dev…
View article: Correction: Transcriptomic analysis of Stropharia rugosoannulata reveals carbohydrate metabolism and cold resistance mechanisms under low-temperature stress
Correction: Transcriptomic analysis of Stropharia rugosoannulata reveals carbohydrate metabolism and cold resistance mechanisms under low-temperature stress Open
View article: Transcriptomic analysis of Stropharia rugosoannulata reveals carbohydrate metabolism and cold resistance mechanisms under low-temperature stress
Transcriptomic analysis of Stropharia rugosoannulata reveals carbohydrate metabolism and cold resistance mechanisms under low-temperature stress Open
Low temperature is an important environmental factor that restricts the growth of Stropharia rugosoannulata ; however, the molecular mechanisms underlying S. rugosoannulata responses to low-temperature stress are largely unknown. In this s…