Jinkui Wang
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View article: NR2F6 promotes the malignant progression of neuroblastoma as an indicator of poor prognosis
NR2F6 promotes the malignant progression of neuroblastoma as an indicator of poor prognosis Open
Background NR2F6 is an orphan nuclear receptor with dual tumorigenic activity in the immune system and tumor cells, playing an essential role in tumor differentiation and immunity. This study aimed to investigate the expression level of NR…
View article: Chemotherapy and Heart-Specific Mortality in Elderly Men with Prostate Cancer: A Propensity Score Matching Analysis
Chemotherapy and Heart-Specific Mortality in Elderly Men with Prostate Cancer: A Propensity Score Matching Analysis Open
Objective Prostate cancer (PC) is the most common malignant tumour in men, and atherosclerotic cardiovascular disease (ASCVD) is the leading cause of non-cancer death in PC patients. The main purpose of this study was to investigate whethe…
View article: Recruitment and polarization typing of tumor-associated macrophages is associated with tumor progression and poor prognosis in Wilms tumor patients
Recruitment and polarization typing of tumor-associated macrophages is associated with tumor progression and poor prognosis in Wilms tumor patients Open
Purpose Tumor-associated macrophages (TAMs) play a crucial role in shaping various tumor microenvironments. However, their recruitment in Wilms tumor (WT), the predominant malignant renal tumor in children, has been inadequately explored. …
View article: ZSTK474 targeting PIK3R3 inhibits the Wilms’ tumor through G0 / G1 phase arrest
ZSTK474 targeting PIK3R3 inhibits the Wilms’ tumor through G0 / G1 phase arrest Open
Purpose Wilms’ tumor (WT), also known as nephroblastoma, is the predominant form of primary malignant renal cancer. The unfavorable prognoses linked to anaplastic nephroblastoma and recurrent nephroblastoma emphasize the crucial requiremen…
View article: Development and validation of competing risk nomograms for predicting cancer‑specific mortality in non-metastatic patients with non‑muscle invasive urothelial bladder cancer
Development and validation of competing risk nomograms for predicting cancer‑specific mortality in non-metastatic patients with non‑muscle invasive urothelial bladder cancer Open
View article: Enhancing clinical decision-making: A novel nomogram for stratifying cancer-specific survival in middle-aged individuals with follicular thyroid carcinoma utilizing SEER data
Enhancing clinical decision-making: A novel nomogram for stratifying cancer-specific survival in middle-aged individuals with follicular thyroid carcinoma utilizing SEER data Open
We developed an innovative nomogram to predict CSS in middle-aged patients with FTC. Our model after a rigorous internal validation and external validation process, based on the time proved that the high level of accuracy and reliability. …
View article: Dual roles of HK3 in regulating the network between tumor cells and tumor-associated macrophages in neuroblastoma
Dual roles of HK3 in regulating the network between tumor cells and tumor-associated macrophages in neuroblastoma Open
View article: A novel nomogram to predict testicular torsion in children with acute scrotal pain: a single-center retrospective study in western China
A novel nomogram to predict testicular torsion in children with acute scrotal pain: a single-center retrospective study in western China Open
This study is the report with the largest sample size on the construction of prediction models for ASP in children in southwestern China. The predictive model we developed demonstrated excellent performance and higher accuracy in predictin…
View article: Design and process of force-electric fusion for electromagnetic driven Si based MEMS S&A
Design and process of force-electric fusion for electromagnetic driven Si based MEMS S&A Open
In order to meet the technical requirements for precise control of the arming time in high-dynamic environments and ammunition safety, this article proposes a silicon-based MEMS safety system force-electric fusion design scheme for small-c…
View article: Integrative analysis with machine learning identifies diagnostic and prognostic signatures in neuroblastoma based on differentially DNA methylated enhancers between INSS stage 4 and 4S neuroblastoma
Integrative analysis with machine learning identifies diagnostic and prognostic signatures in neuroblastoma based on differentially DNA methylated enhancers between INSS stage 4 and 4S neuroblastoma Open
Introduction Accumulating evidence demonstrates that aberrant methylation of enhancers is crucial in gene expression profiles across several cancers. However, the latent effect of differently expressed enhancers between INSS stage 4S and 4…
View article: Establishment and validation of nomograms to predict the overall survival and cancer-specific survival for non-metastatic bladder cancer patients: A large population-based cohort study and external validation
Establishment and validation of nomograms to predict the overall survival and cancer-specific survival for non-metastatic bladder cancer patients: A large population-based cohort study and external validation Open
This study aimed to develop nomograms to accurately predict the overall survival (OS) and cancer-specific survival (CSS) of non-metastatic bladder cancer (BC) patients. Clinicopathological information of 260,412 non-metastatic BC patients …
View article: Prognostic significance of surgery and radiotherapy in elderly patients with localized prostate cancer: establishing and time-based external validation a nomogram from SEER-based study
Prognostic significance of surgery and radiotherapy in elderly patients with localized prostate cancer: establishing and time-based external validation a nomogram from SEER-based study Open
View article: Activation of the p53 signaling pathway by piRNA-MW557525 overexpression induces a G0/G1 phase arrest thus inhibiting neuroblastoma growth
Activation of the p53 signaling pathway by piRNA-MW557525 overexpression induces a G0/G1 phase arrest thus inhibiting neuroblastoma growth Open
Background Neuroblastoma (NB) is the most common extracranial malignant solid tumor in children. Due to drug resistance to radiotherapy and chemotherapy, mainly due to the existence of cancer stem cells (CSCs), some children still have a p…
View article: Correction: Survival benefits and challenges of adjuvant chemotherapy for high-grade osteosarcoma: a population-based study
Correction: Survival benefits and challenges of adjuvant chemotherapy for high-grade osteosarcoma: a population-based study Open
View article: The PI3K-AKT-mTOR signaling pathway mediates the cytoskeletal remodeling and epithelial-mesenchymal transition in bladder outlet obstruction
The PI3K-AKT-mTOR signaling pathway mediates the cytoskeletal remodeling and epithelial-mesenchymal transition in bladder outlet obstruction Open
View article: ZSTK474 Targeting PIK3R3 Inhibits the Wilms' Tumor through G0 / G1 Phase Arrest
ZSTK474 Targeting PIK3R3 Inhibits the Wilms' Tumor through G0 / G1 Phase Arrest Open
Purpose Wilms' tumor (WT) is children's most common primary kidney malignancy. The prognosis of patients with anaplastic and recurrent nephroblastoma is still poor. Therefore, searching for a new potential medicinal agent for WT is urgent.…
View article: Development and validation of a nomogram to predict cancer-specific survival in nonsurgically treated elderly patients with prostate cancer
Development and validation of a nomogram to predict cancer-specific survival in nonsurgically treated elderly patients with prostate cancer Open
View article: Human Mesenchymal Stem Cells-Derived Exosome Mimetic Vesicles Regulation of the MAPK Pathway and ROS Levels Inhibits Glucocorticoid-Induced Apoptosis in Osteoblasts
Human Mesenchymal Stem Cells-Derived Exosome Mimetic Vesicles Regulation of the MAPK Pathway and ROS Levels Inhibits Glucocorticoid-Induced Apoptosis in Osteoblasts Open
Background. Long-term extensive use of glucocorticoids will lead to hormonal necrosis of the femoral head, and osteoblasts play an important role in the prevention of osteonecrosis. However, there is no complete cure for necrosis of the fe…
View article: NR2F6 promotes the malignant progression of neuroblastoma as an indicator of poor prognosis
NR2F6 promotes the malignant progression of neuroblastoma as an indicator of poor prognosis Open
Background NR2F6 is an orphan nuclear receptor with dual tumorigenic activity in the immune system and tumor cells, playing an essential role in tumor differentiation and immunity. This study aimed to investigate the expression level of NR…
View article: Establishment and validation of a competitive risk model for predicting cancer-specific survival in patients with osteosarcoma: a population-based study
Establishment and validation of a competitive risk model for predicting cancer-specific survival in patients with osteosarcoma: a population-based study Open
View article: Research on Fault Diagnosis Method of Rotary Machinery Based on Improved Transformer
Research on Fault Diagnosis Method of Rotary Machinery Based on Improved Transformer Open
In modern industry, rotating machinery plays a crucial role. These rotating machines are not only fundamental components of power generation and propulsion systems but also key factors for their efficient operation. Harsh operating environ…
View article: Survival benefits and challenges of adjuvant chemotherapy for high-grade osteosarcoma: a population-based study
Survival benefits and challenges of adjuvant chemotherapy for high-grade osteosarcoma: a population-based study Open
Background Osteosarcoma is the most prevalent primary malignant bone tumor. The primary treatment for osteosarcoma is a combination of chemotherapy and surgery. However, there has been no recent progress in the role of chemotherapy in impr…
View article: Surveillance of prognostic risk factors in patients with SCCB using artificial intelligence: a retrospective study
Surveillance of prognostic risk factors in patients with SCCB using artificial intelligence: a retrospective study Open
View article: BI-D1870 Induces Mitotic Dysfunction and Apoptosis in Neuroblastoma by Regulating the PI3K-Akt-mTORC1 Signal Axis
BI-D1870 Induces Mitotic Dysfunction and Apoptosis in Neuroblastoma by Regulating the PI3K-Akt-mTORC1 Signal Axis Open
Introduction: Neuroblastoma (NB) is one of the most common extracranial solid malignant tumors in children. The 5-year survival rate of high-risk or refractory NB is less than 50%. Therefore, developing new effective therapeutics for NB re…
View article: Survival benefit of breast-conserving surgery with adjuvant radiotherapy for young women with ductal carcinoma in situ: A population-based cohort study
Survival benefit of breast-conserving surgery with adjuvant radiotherapy for young women with ductal carcinoma in situ: A population-based cohort study Open
View article: Development and validation of a nomogram to predict cancer-specific survival for Asian/Pacific Islander patients with renal cell carcinoma
Development and validation of a nomogram to predict cancer-specific survival for Asian/Pacific Islander patients with renal cell carcinoma Open
View article: Comparison of Efficacy and Late Kidney Effects Between Nephron Sparing Surgery and Radical Nephrectomy in Unilateral Wilms Tumor: A Systematic Review and Meta-Analysis
Comparison of Efficacy and Late Kidney Effects Between Nephron Sparing Surgery and Radical Nephrectomy in Unilateral Wilms Tumor: A Systematic Review and Meta-Analysis Open
Review question / Objective: Compare the efficacy and late kidney effects between Nephron Sparing Surgery (NSS) and Radical Nephrectomy (RN) in the management of unilateral Wilms Tumor (WT) patients.Studies were either randomized controlle…
View article: A nomogram for predicting cancer-specific survival and overall survival in elderly patients with nonmetastatic renal cell carcinoma
A nomogram for predicting cancer-specific survival and overall survival in elderly patients with nonmetastatic renal cell carcinoma Open
Background Renal cell carcinoma (RCC) is a common malignant tumor in the elderly, with an increasing trend in recent years. We aimed to construct a nomogram of cancer-specific survival (CSS) and overall survival (OS) in elderly patients wi…
View article: Development and Validation a nomogram to predict the risk of pulmonary metastasis in pediatric osteosarcoma
Development and Validation a nomogram to predict the risk of pulmonary metastasis in pediatric osteosarcoma Open
Background Most malignant bone tumors in children and adolescents are osteosarcomas. Pediatric osteosarcoma has a high mortality rate due to pulmonary metastasis, which occurs in a short period of time. We would like to establish a nomogra…
View article: Development and validation of a survival nomogram for muscle-invasive bladder cancer in the elderly: using competing risk models and propensity matching to apply the prediction tool
Development and validation of a survival nomogram for muscle-invasive bladder cancer in the elderly: using competing risk models and propensity matching to apply the prediction tool Open
Aim: Patients with muscle-invasive bladder cancer (MIBC) have a low survival rate, with a 5-year survival of approximately 45%, regardless of the treatment received. The risk of death within 5 years after radical cystectomy in patients wit…