Jinlong Luo
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View article: Effects of Various Drying Parameters on the Volatile and Non-Volatile Compositions of ‘Qiancha 1’ White Tea
Effects of Various Drying Parameters on the Volatile and Non-Volatile Compositions of ‘Qiancha 1’ White Tea Open
‘Qiancha 1’ is an excellent raw material for manufacturing white tea. The effects of different drying parameters on the quality performance of ‘Qiancha 1’ white tea remain poorly understood, which restricts the precise regulation of the qu…
View article: Pulmonary and Extrapulmonary Effects of Prolonged Prone Positioning in a Porcine Model of Acute Respiratory Distress Syndrome
Pulmonary and Extrapulmonary Effects of Prolonged Prone Positioning in a Porcine Model of Acute Respiratory Distress Syndrome Open
Background: Prone positioning (PP) improves survival in severe acute respiratory distress syndrome (ARDS), but its prolonged effects on pulmonary and extrapulmonary organs remain unclear. This study aimed to investigate the pathophysiologi…
View article: Association of albumin-bilirubin grade with short- and long-term mortality in patients with heart failure: a cohort study using restricted cubic splines and propensity score matching
Association of albumin-bilirubin grade with short- and long-term mortality in patients with heart failure: a cohort study using restricted cubic splines and propensity score matching Open
Objective Heart failure (HF) is a chronic progressive syndrome caused by a variety of cardiovascular diseases and is associated with high morbidity, mortality, and healthcare burden. Forecasting the prognosis of HF patients at an early sta…
View article: Edaravone alleviates sepsis-induced diaphragmatic dysfunction via Sirt1/Nrf2 pathway
Edaravone alleviates sepsis-induced diaphragmatic dysfunction via Sirt1/Nrf2 pathway Open
Edaravone was demonstrated to potentially alleviate SIDD by activating the SIRT1/Nrf2 pathway.
View article: How Is Middle-Class Parents’ Education Anxiety Generated? A Study Based on a Survey of Home Education of Junior Secondary School Students in 8 Provinces and Cities
How Is Middle-Class Parents’ Education Anxiety Generated? A Study Based on a Survey of Home Education of Junior Secondary School Students in 8 Provinces and Cities Open
Drawing on a 2022 survey of home education of junior secondary school students in China’ eight provincial administrative regions, this study seeks to examine the chief factors influencing the generation of education anxiety in Chinese midd…
View article: Autophagy in Muscle Regeneration: Mechanisms, Targets, and Therapeutic Perspective
Autophagy in Muscle Regeneration: Mechanisms, Targets, and Therapeutic Perspective Open
Autophagy maintains the stability of eukaryotic cells by degrading unwanted components and recycling nutrients and plays a pivotal role in muscle regeneration by regulating the quiescence, activation, and differentiation of satellite cells…
View article: Effects of oral probiotics on inflammation and intestinal function in adult patients after appendectomy: Randomized controlled trial
Effects of oral probiotics on inflammation and intestinal function in adult patients after appendectomy: Randomized controlled trial Open
BACKGROUND Appendectomy is an acute abdominal surgery that is often accompanied by severe abdominal inflammation. Oral probiotics are one of the postoperative treatments for rapid rehabilitation. However, there is a lack of prospective stu…
View article: Protective role of pretreatment with Anisodamine against sepsis-induced diaphragm atrophy via inhibiting JAK2/STAT3 pathway
Protective role of pretreatment with Anisodamine against sepsis-induced diaphragm atrophy via inhibiting JAK2/STAT3 pathway Open
There is an increasing tendency for sepsis patients to suffer from diaphragm atrophy as well as mortality. Therefore, reducing diaphragm atrophy could benefit sepsis patients' prognoses. Studies have shown that Anisodamine (Anis) can exert…
View article: N-Acetylcysteine Attenuates Sepsis-Induced Muscle Atrophy by Downregulating Endoplasmic Reticulum Stress
N-Acetylcysteine Attenuates Sepsis-Induced Muscle Atrophy by Downregulating Endoplasmic Reticulum Stress Open
(1) Background: Sepsis-induced muscle atrophy is characterized by a loss of muscle mass and function which leads to decreased quality of life and worsens the long-term prognosis of patients. N-acetylcysteine (NAC) has powerful antioxidant …
View article: Correlation analysis of secondary metabolites and disease resistance activity of different varieties of Congou black tea based on LC-MS/MS and TCMSP
Correlation analysis of secondary metabolites and disease resistance activity of different varieties of Congou black tea based on LC-MS/MS and TCMSP Open
To investigate the correlation between the difference of secondary metabolites and the disease-resistance activity of different varieties of Congou black tea. Among a total of 657 secondary metabolites identified, 183 metabolites had anti-…
View article: A commentary on ‘Survival benefit and impact of adjuvant chemotherapy following systemic neoadjuvant chemotherapy in patients with resected pancreas ductal adenocarcinoma: a retrospective cohort study’
A commentary on ‘Survival benefit and impact of adjuvant chemotherapy following systemic neoadjuvant chemotherapy in patients with resected pancreas ductal adenocarcinoma: a retrospective cohort study’ Open
aDepartment of General Surgery of Huidong, Zigong Fourth People's Hospital, Zigong, 643000, Sichuan Province, China bDepartment of Ultrasound, Zigong Hospital of Woman and Children Healthcare, Zigong, 643000, Sichuan Province, China Sponso…
View article: Ameliorative Effects of Osthole on Experimental Renal Fibrosis in vivo and in vitro by Inhibiting IL-11/ERK1/2 Signaling
Ameliorative Effects of Osthole on Experimental Renal Fibrosis in vivo and in vitro by Inhibiting IL-11/ERK1/2 Signaling Open
Objectives: Natural product, osthole, has been proven to have a protective effect on organ fibrosis, including renal fibrosis. All of these studies are mainly focused on the regulation of TGF-β/Smad signaling pathway. However, due to the p…
View article: Prognostic Model for Mortality of Hospitalized Patients with COVID-19 Pneumonia in Wuhan, China: A Multi-center retrospective cohort study
Prognostic Model for Mortality of Hospitalized Patients with COVID-19 Pneumonia in Wuhan, China: A Multi-center retrospective cohort study Open
Background: Novel coronavirus (COVID-19) infection is a global public health issue and has now affected more than 70 countries worldwide. Severe adult respiratory syndrome-CoV-2 (SARS-CoV-2) pneumonia is associated with high risk of mortal…
View article: Survival Factors and Metabolic Pathogenesis in Elderly Patients (≥65) with COVID-19 : A multi- center study of 223 Cases
Survival Factors and Metabolic Pathogenesis in Elderly Patients (≥65) with COVID-19 : A multi- center study of 223 Cases Open
BackgroundElderly patients infected with COVID-19 are reported to be facing a substantially increased risk of mortality. Clinical characteristics, treatment options, and potential survival factors remain under investigation. This study aim…
View article: Jia-Wei-Jiao-Tai-Wan ameliorates type 2 diabetes by improving β cell function and reducing insulin resistance in diabetic rats
Jia-Wei-Jiao-Tai-Wan ameliorates type 2 diabetes by improving β cell function and reducing insulin resistance in diabetic rats Open
This study suggests that JWJTW can ameliorate type 2 diabetes by improving β cell function and reducing insulin resistance in diabetic rats.
View article: Reduced Expression of Glutathione S-Transferase α 4 Promotes Vascular Neointimal Hyperplasia in CKD
Reduced Expression of Glutathione S-Transferase α 4 Promotes Vascular Neointimal Hyperplasia in CKD Open
Neointima formation is the leading cause of arteriovenous fistula (AVF) failure. We have shown that CKD accelerates this process by transforming the vascular smooth muscle cells (SMCs) lining the AVF from a contractile to the synthetic phe…
View article: Yap/Taz Deletion in Gli+ Cell-Derived Myofibroblasts Attenuates Fibrosis
Yap/Taz Deletion in Gli+ Cell-Derived Myofibroblasts Attenuates Fibrosis Open
In damaged kidneys, increased extracellular matrix (ECM) and tissue stiffness stimulate kidney fibrosis through incompletely characterized molecular mechanisms. The transcriptional coactivators yes-associated protein (Yap) and transcriptio…
View article: Developing the control system for a novel electric medical operation table
Developing the control system for a novel electric medical operation table Open
At present, most of the operation table has single functions and own drawbacks like high cost, and difficult to repair after failure.In this context, a novel control system of the electric operation table is proposed in this paper.The cont…
View article: Serum Glucocorticoid–Regulated Kinase 1 Blocks CKD–Induced Muscle Wasting Via Inactivation of FoxO3a and Smad2/3
Serum Glucocorticoid–Regulated Kinase 1 Blocks CKD–Induced Muscle Wasting Via Inactivation of FoxO3a and Smad2/3 Open
Muscle proteolysis in CKD is stimulated when the ubiquitin-proteasome system is activated. Serum glucocorticoid–regulated kinase 1 (SGK-1) is involved in skeletal muscle homeostasis, but the role of this protein in CKD–induced muscle wasti…
View article: FSP-1 Impairs the Function of Endothelium Leading to Failure of Arteriovenous Grafts in Diabetic Mice
FSP-1 Impairs the Function of Endothelium Leading to Failure of Arteriovenous Grafts in Diabetic Mice Open
To understand how endothelial cell (EC) dysfunction contributes to the failure of arteriovenous graft (AVG), we investigated the role of fibroblast-specific protein 1 (FSP-1) in cultured ECs and a mouse AVG model. In vitro, we uncovered a …