Jun Zhang
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View article: Global, regional, and national burden of polycystic ovary syndrome, 1990–2021: a comprehensive analysis of trends and projections based on the global burden of disease 2021 study
Global, regional, and national burden of polycystic ovary syndrome, 1990–2021: a comprehensive analysis of trends and projections based on the global burden of disease 2021 study Open
Polycystic ovarian syndrome (PCOS) is a major endocrine disorder that affects women of reproductive age. This study evaluated global disease burden trends (1990-2021) and projected future trajectories to 2050 to inform public health strate…
View article: Delineating multiobjective ecological management zones and revealing scale effects of thresholds for factors influencing ecosystem services in Jiangxi Province
Delineating multiobjective ecological management zones and revealing scale effects of thresholds for factors influencing ecosystem services in Jiangxi Province Open
Elucidating the connection between the total supply and demand of ecosystem services (ESTSD) can provide comprehensive decision support for regional eco-management. Previous studies have focused on the spatial and temporal evolution of EST…
View article: Metallogenic model and deep ore prospecting direction of the Zhazixi Sb-W-Au deposit in Western Hunan, South China
Metallogenic model and deep ore prospecting direction of the Zhazixi Sb-W-Au deposit in Western Hunan, South China Open
The Zhazixi Sb-W-Au deposit is a typical quartz vein-type located in the Xuefeng curved metallogenic belt, Hunan Province. However, the genetic mechanism and metallogenic regularity of the deposit remain poorly understood, and the occurren…
View article: Making Pre‐Procedural Pain Assessment Standard in Cancer Care
Making Pre‐Procedural Pain Assessment Standard in Cancer Care Open
View article: AN02, a Naovel Curcumin Derivative, Orchestrates APC‐SMAD4‐Mediated CTLA‐4 Degradation for Ovarian Cancer Therapy
AN02, a Naovel Curcumin Derivative, Orchestrates APC‐SMAD4‐Mediated CTLA‐4 Degradation for Ovarian Cancer Therapy Open
Curcumin is a natural polyphenolic compound extracted from the rhizomes of Curcuma longa , exhibiting a wide range of biological activities, including anti‐inflammatory, antioxidant, antitumor, antibacterial, antiviral, and neuroprotective…
View article: Artificial Intelligence Enhanced Electrocardiogram Analysis for Age and Sex Classification in Youth
Artificial Intelligence Enhanced Electrocardiogram Analysis for Age and Sex Classification in Youth Open
Introduction Electrocardiogram (ECG) values vary significantly across age and sex, particularly during childhood and adolescence. While age- and sex-specific ECG standards exist, they often fail to capture complex multi-dimensional relatio…
View article: Multi-channel deep learning radiomics model based on contrast-enhanced CT for predicting postoperative prognosis in laryngeal carcinoma
Multi-channel deep learning radiomics model based on contrast-enhanced CT for predicting postoperative prognosis in laryngeal carcinoma Open
View article: Artemisia frigida Willd.: Advances in Traditional Uses, Phytochemical Constituents, Extraction and Separation Methods, and Pharmacological Activities
Artemisia frigida Willd.: Advances in Traditional Uses, Phytochemical Constituents, Extraction and Separation Methods, and Pharmacological Activities Open
Artemisia frigida Willd. (A. frigida), a traditional medicinal herb widely distributed in northern China, Mongolia, and Siberia, has garnered increasing scientific interest due to its diverse phytochemical profile and extensive pharmacolog…
View article: Cerebellar transcranial direct current stimulation combined with virtual reality training for the balance of older adults: study protocol for a randomized controlled trial
Cerebellar transcranial direct current stimulation combined with virtual reality training for the balance of older adults: study protocol for a randomized controlled trial Open
Background Falls are a major public safety issue, and improving the posture control ability of elderly people is highly important for preventing falls. Transcranial direct current stimulation (tDCS) and virtual reality-based balance traini…
View article: A hybrid feature-based heterogeneous graph transformer method for cheating official account mining
A hybrid feature-based heterogeneous graph transformer method for cheating official account mining Open
As cheating official accounts (COAs) in social media has posed a significant threat to society, how to detect COAs has attracted increasing attention worldwide. However, mining COAs is challenging because the COAs are always much fewer tha…
View article: Comment on “Sex differences in the relationship between obesity and hypertension in Japan: A large population-based cross-sectional study”
Comment on “Sex differences in the relationship between obesity and hypertension in Japan: A large population-based cross-sectional study” Open
View article: Current perspectives on the pathogenesis of cerebral atherosclerosis
Current perspectives on the pathogenesis of cerebral atherosclerosis Open
(1) Pathophysiological processes: Endothelial dysfunction and oxidative stress are crucial in the early stage of atherosclerotic plaque formation. Lipid accumulation, especially of low-density lipoprotein, promotes plaque growth and instab…
View article: The bidirectional relationship between social participation, social media use and depressive symptoms: a nationwide longitudinal study
The bidirectional relationship between social participation, social media use and depressive symptoms: a nationwide longitudinal study Open
Continuous social participation may enhance social media use competency and alleviate depressive symptoms in older adults. Social media use may alleviate the decrease in social participation frequency and increase in depressive symptoms in…
View article: Pervasive splicing in a plant DNA virus
Pervasive splicing in a plant DNA virus Open
Viruses maximize their limited coding space through strategies that increase transcript and protein diversity. In mammalian viruses, splicing is a well-established mechanism for proteome expansion, yet in plant viruses it is considered ext…
View article: Assessment of cerebral hemodynamic changes in acute ischemic stroke patients following mechanical thrombectomy using CT perfusion imaging
Assessment of cerebral hemodynamic changes in acute ischemic stroke patients following mechanical thrombectomy using CT perfusion imaging Open
Background Acute ischemic stroke (AIS) is a leading cause of disability and death in China, with mechanical thrombectomy (MT) being an effective treatment for AIS due to large vessel occlusion (LVO). The aim of this study was to evaluate t…
View article: Effects of grazing on plant functional groups across spatial scales in Stipa breviflora desert steppe
Effects of grazing on plant functional groups across spatial scales in Stipa breviflora desert steppe Open
This study investigated the Stipa breviflora desert steppe through multi-scale (50m×50m, 25m×25m, 2.5m×2.5m) and grazing intensity (no grazing vs. heavy grazing) comparative analyses, revealing the response mechanisms of plant functional g…
View article: Low-Altitude Wireless Networks: A Comprehensive Survey
Low-Altitude Wireless Networks: A Comprehensive Survey Open
The rapid development of the low-altitude economy has imposed unprecedented demands on wireless infrastructure to accommodate large-scale drone deployments and facilitate intelligent services in dynamic airspace environments. However, unlo…
View article: Deep holes of a class of twisted Reed-Solomon codes
Deep holes of a class of twisted Reed-Solomon codes Open
The deep hole problem is a fundamental problem in coding theory, and it has many important applications in code constructions and cryptography. The deep hole problem of Reed-Solomon codes has gained a lot of attention. As a generalization …
View article: Exploring the Impact of Urban Characteristics on Diurnal Land Surface Temperature Based on LCZ and Machine Learning
Exploring the Impact of Urban Characteristics on Diurnal Land Surface Temperature Based on LCZ and Machine Learning Open
The urban heat island (UHI) effect has become a critical environmental issue affecting urban livability and public health, attracting widespread attention from both academia and society. Although numerous studies have examined the influenc…
View article: New strategies for tumor diagnosis and therapy with ultrasound assisted by nanomaterials
New strategies for tumor diagnosis and therapy with ultrasound assisted by nanomaterials Open
View article: PepCCD: A Contrastive Conditioned Diffusion Framework for Target-Specific Peptide Generation
PepCCD: A Contrastive Conditioned Diffusion Framework for Target-Specific Peptide Generation Open
Peptide-based drug design targeting “undruggable” proteins remains one of the most critical challenges in modern drug discovery. Conventional peptide-discovery pipelines rely on low-throughput experimental screening, which is both time-con…
View article: Integrating single-cell RNA sequencing and artificial intelligence for multitargeted drug design for combating resistance in liver cancer
Integrating single-cell RNA sequencing and artificial intelligence for multitargeted drug design for combating resistance in liver cancer Open
View article: MolSculptor: an adaptive diffusion-evolution framework enabling generative drug design for multi-target affinity and selectivity
MolSculptor: an adaptive diffusion-evolution framework enabling generative drug design for multi-target affinity and selectivity Open
The rational design of molecules with tailored activity/selectivity across multiple protein targets is crucial for developing therapies for complex diseases like cancer, yet remains a formidable challenge. While deep generative models show…
View article: Bidirectional Sparse Attention for Faster Video Diffusion Training
Bidirectional Sparse Attention for Faster Video Diffusion Training Open
Video diffusion Transformer (DiT) models excel in generative quality but hit major computational bottlenecks when producing high-resolution, long-duration videos. The quadratic complexity of full attention leads to prohibitively high train…
View article: Ecological Resilience and Sustainable Development: Dynamic Assessment and Evolution Mechanisms of Landscape Patterns and Ecotourism Suitability in the Yangtze River Delta Region
Ecological Resilience and Sustainable Development: Dynamic Assessment and Evolution Mechanisms of Landscape Patterns and Ecotourism Suitability in the Yangtze River Delta Region Open
Ecotourism, as a resilient and sustainable form of tourism, plays an increasingly vital role in regional economic growth and ecological conservation, particularly in the face of challenges such as climate change and rapid urbanization. Thi…
View article: Forming quality control of Laser Powder Bed Fusion GH3536 alloy: Surface quality, defects, and microstructure
Forming quality control of Laser Powder Bed Fusion GH3536 alloy: Surface quality, defects, and microstructure Open
This study investigates the influence of volume energy density (VED) on surface quality, density, defects, and microstructure of laser powder bed fusion (L-PBF) GH3536 alloy. Specimens fabricated below 80 J/mm3 exhibit lack-of-fusion pores…
View article: DreamSwapV: Mask-guided Subject Swapping for Any Customized Video Editing
DreamSwapV: Mask-guided Subject Swapping for Any Customized Video Editing Open
With the rapid progress of video generation, demand for customized video editing is surging, where subject swapping constitutes a key component yet remains under-explored. Prevailing swapping approaches either specialize in narrow domains-…
View article: Shape memory hydrogels in tissue engineering: Recent advances and challenges
Shape memory hydrogels in tissue engineering: Recent advances and challenges Open
Shape memory hydrogels (SMHs) have emerged as transformative materials in tissue engineering, owing to their unique ability to recover their original shape after deformation. These hydrogels combine hydrophilicity and elasticity with shape…
View article: CHH demethylation in the ZmGST2 promoter enhances maize drought tolerance by regulating ROS scavenging and root growth
CHH demethylation in the ZmGST2 promoter enhances maize drought tolerance by regulating ROS scavenging and root growth Open
As an important food crop worldwide, maize is frequently impacted by drought stress. It is of great significance to study its drought resistance genes and mechanisms, in which DNA methylation modification in the promoter region plays a key…
View article: Psychological dilemmas and distress among Chinese primiparas during the postpartum transition underlying implicit cultural norms: a phenomenological inquiry
Psychological dilemmas and distress among Chinese primiparas during the postpartum transition underlying implicit cultural norms: a phenomenological inquiry Open
Postpartum distress among first-time mothers in China is not solely an individual psychological experience, but rather a complex phenomenon shaped by the interplay between traditional cultural customs and contemporary social transformation…