Explanipedia

Effects of cumulative lifetime estrogen exposure on the clinical characteristics and courses in postmenopausal women with rheumatoid arthritis Open

Eun Hye Park, Sang Tae Choi, Jung Soo Song, Eun Ha Kang, Yun Jong Lee , et al. · 2025

Patients with RA and lower CLEE had higher disease activity, more erosive disease, and worse PROs than those with a higher CLEE. Lower CLEE adversely affects longitudinal changes in disease activity and PROs and is associated with a lower …

Comparing the Efficacy and Safety of Fexuprazan and Lansoprazole for the Prevention of Nonsteroidal Anti-inflammatory Drug-Induced Peptic Ulcer Open

Seokchan Hong, Ji Hyeon Ju, Sang‐Heon Lee, Seung‐Jae Hong, Sang-Hyon Kim , et al. · 2025

Given its non-inferiority to lansoprazole and similar safety profile, fexuprazan is a promising alternative for the prevention of NSAID-induced PUs (ClinicalTrials.gov identifier NCT04784910).

Efficacy and safety of epaminurad, a potent hURAT1 inhibitor, in patients with gout: a randomized, placebo-controlled, dose-finding study Open

Jae‐Bum Jun, Hye‐Soon Lee, Sang-Hyon Kim, Seung‐Geun Lee, Doo‐Ho Lim , et al. · 2025

Effects of Cumulative Lifetime Estrogen Exposure on the Clinical Characteristics and Courses in Postmenopausal Women with Rheumatoid Arthritis Open

Eun Hye Park, Jung Soo Song, Eun Ha Kang, Yun Jong Lee, You‐Jung Ha · 2025

Awareness of and Experience in a Polypharmacy Management Program for Older Inpatients: A Qualitative Study of Patients, Caregivers, Physicians, and Pharmacists Open

Woo-Young Shin, Seonah Kim, Jung‐Ha Kim, Jung Soo Song · 2024

Current state and prospects of gout treatment in Korea Open

Eun Hye Park, Sang Tae Choi, Jung Soo Song · 2022

Effective management of gout includes the following: appropriate control of gout flares; lifestyle modifications; management of comorbidities; and long-term urate-lowering therapy (ULT) to prevent subsequent gout flares, structural joint d…

Polypharmacy Management Program: Current Status and Emerging Challenges in Older Patients Open

Woo-Young Shin, Jung Soo Song, Jung‐Ha Kim · 2021

Polypharmacy is a major public health concern globally with aging populations and the increase in the prevalence of multimorbidity.This review provides an overview of polypharmacy and its management programs in older patients and describes…

Cardiovascular risk associated with allopurinol vs. benzbromarone in patients with gout Open

Eun Ha Kang, Eun Hye Park, Anna Shin, Jung Soo Song, Seoyoung C. Kim · 2021

Aims With the high prevalence of gout and associated cardiovascular (CV) diseases, information on the comparative CV safety of individual urate-lowering drugs becomes increasingly important. However, few studies examined the CV risk of uri…

Diagnosis and Treatment of Rheumatic Diseases Important to the Elderly Open

Jung Soo Song · 2021

Patient Perspectives and Preferences Regarding Gout and Gout Management: Impact on Adherence Open

Kyung Min Chung, Sung-Soo Kim, Yun‐Hong Cheon, Seung‐Jae Hong, Hyo Jin Choi , et al. · 2021

Patients' perspectives and management preferences had high impacts on adherence to ULT in gout. Consideration of patients' perspectives and preferences is important for achieving the desired clinical outcome in gout.

Trends of Gout Prevalence in South Korea Based on Medical Utilization: A National Health Insurance Service Database (2002∼2015) Open

Jin Su Park, Minjin Kang, Jung Soo Song, Hyun Lim, Chan Hee Lee · 2020

Objective.Although gout is the most common form of inflammatory arthritis, data on gout prevalence and management are sparse, especially in Korean populations.This study reevaluated the most recent prevalence and incidence of gout values i…

Low levels of serum urate are associated with a higher prevalence of depression in older adults: a nationwide cross-sectional study in Korea Open

Woo Joong Kim, Hye Ri Kim, Jung Soo Song, Sang Tae Choi · 2020

Seasonal Variations and Associated Factors of Gout Attacks: a Prospective Multicenter Study in Korea Open

Hyo Jin Choi, Ki Won Moon, Hyun Ok Kim, Yeon‐Ah Lee, Seung‐Jae Hong , et al. · 2020

In this prospective study, the most common season and month of gout attacks in Korea are spring and March, respectively. Alcohol is the most common provoking factor, particularly during summer. Diurnal temperature changes on the day of the…

What is the Best Choice for Urate-lowering Therapy for Korean? Open

Yun‐Hong Cheon, Jung Soo Song · 2020

Gout is one of the most common forms of acute inflammatory arthritis caused by long-standing hyperuricemia. Various clinical and epidemiological studies have demonstrated that uric acid, which is strongly associated with the pathogenesis o…

The Utility of the Random Urine Uric Acid-to-Creatinine Ratio for Patients with Gout Who Need Uricosuric Agents: Retrospective Cross-Sectional Study Open

Sang Tae Choi, Jung Soo Song, Seung Jun Kim, Chan Ho Kim, Sung Jin Moon · 2020

There is a moderate positive correlation between the random urinary UA/CR ratio and 24-hour urine uric acid excretion, so that UA/CR ratio may not be a good predictor of 24-hour urine uric acid excretion. However, the random urine UA/CR ra…

The Role of a “Treat-to-Target” Approach in the Long-Term Renal Outcomes of Patients with Gout Open

Woo Joong Kim, Jung Soo Song, Sang Tae Choi · 2019

Background: Although gout is accompanied by the substantial burden of kidney disease, there are limited data to assess renal function as a therapeutic target. This study evaluated the importance of implementing a “treat-to-target” approach…

Simplified disease activity changes in real-world practice: a nationwide observational study of seropositive rheumatoid arthritis patients with moderate-to-high disease activity Open

Kichul Shin, Sung-Soo Kim, Sang‐Heon Lee, Seung‐Jae Hong, Sung Jae Choi , et al. · 2019

There was a significant reduction in SDAI within 12 months after receiving DMARDs in Korean seropositive RA patients irrespective of bDMARD or cDMARD use in real-world practice. Clinical remission was achieved in those with lower baseline …

Increased Carotid Intima-Media Thickness (IMT) in Hyperuricemic Individuals May Be Explained by Hyperhomocysteinemia Associated with Renal Dysfunction: a Cross-Sectional Study Open

Ji Ho Park, Jung Soo Song, Sang Tae Choi · 2019

These results suggest that renal function impairment in hyperuricemic patients may worsen carotid IMT by increasing serum Hcy levels.

Development of a Consensus List of Potentially Inappropriate Medications for Korean Older Adults Open

Moo-Young Kim, Christopher Etherton‐Beer, Chae-Bong Kim, Jong Lull Yoon, Hyuk Ga , et al. · 2018

We presented a "user-friendly" PIMs list for Korean older adults. Further prospective studies to validate its usefulness in clinical settings and regular updating of the list are required. It is also important to disseminate this list to d…

New Classification Criteria and Guideline for Management of Gout Open

Jung Soo Song · 2018

Gout is a chronic systemic metabolic disease characterized by recurrent attacks of inflammatory arthritis resulting from the precipitation of monosodium urate crystals, which has various clinical and pathological manifestations. The diseas…

SAT0372 Increased carotid intima-media thickness in hyperuricemic individuals may be explained by hyperhomocysteinemia associated with renal dysfunction Open

Sang Tae Choi, Jae-Hyun Park, Jung Soo Song, E.-J. Kang, K.-H. Lee · 2018

EP-1264: Metabolic response and change in CEA level in rectal cancer patients treated with neoadjuvant CRT Open

T.K. Nam, Joon Jeong, Keun Soo Ahn, Y. Kim, Myung Hee Yoon , et al. · 2017

Monthly Oral Ibandronate Reduces Bone Loss in Korean Women With Rheumatoid Arthritis and Osteopenia Receiving Long-term Glucocorticoids: A 48-week Double-blinded Randomized Placebo-controlled Investigator-initiated Trial Open

Kichul Shin, Sung‐Hwan Park, Won Park, Han Joo Baek, Yun Jong Lee , et al. · 2017

Rivaroxaban for Thromboprophylaxis in Patients with Antiphospholipid Syndrome Open

Ji Ho Park, Jung Soo Song, Sang Tae Choi · 2017

The main treatment for Antiphospholipid syndrome (APS) is long-term anticoagulation with an oral vitamin K antagonist, although these are associated with numerous problems. Rivaroxaban is a direct anti-factor Xa inhibitor, with a predictab…

Rising a Novel Weapon in the War against Gout and Hyperuricemia Open

Jung Soo Song · 2016

Serum Procalcitonin as a Useful Serologic Marker for Differential Diagnosis between Acute Gouty Attack and Bacterial Infection Open

Sang Tae Choi, Jung Soo Song · 2016

Serum PCT levels were significantly lower in patients with acute gouty attack than in patients with bacterial infection. Thus, serum PCT can be used as a useful serologic marker to differentiate between acute gouty arthritis and bacterial …

Two-year Follow-up Study of the Relationship between the Changes of Serum Homocysteine and Those of Serum Uric Acid Levels, Lipid Profiles and Renal Function in Gout Patients Open

Eun Hye Park, Ji Ho Park, Jung Soo Song, Sang Tae Choi · 2016

Objective Gout is known to be associated with cardiovascular disease (CVD), and hyperhomocysteinemia is one of the risk factors for CVD. We investigated the associations between the change of serum homocysteine (Hcy) level and those of the…

Recent advances in management of gout Open

Jung Soo Song · 2016

Gout, which is caused by the deposition of monosodium urate crystals in synovial fluid and other tissues, is the most common inflammatory rheumatic disease in men, at least in the Western world, and is increasing in prevalence worldwide. I…

Seasonality of Gout in Korea: A Multicenter Study Open

Hyo Jin Choi, Chan Hee Lee, Joo‐Hyun Lee, Bo Young Yoon, Hyoun‐Ah Kim , et al. · 2015

The object of this study was to evaluate the seasonality of gout in Korea. We retrospectively examined data from 330 patients seen at nine rheumatology clinics, treated with urate lowering therapy (ULT) more than one year after stopping pr…

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