Explanipedia

HLA-B*15:01-positive severe COVID-19 patients lack CD8 <sup>+</sup> T cell pools with highly expanded public clonotypes Open

Louise C. Rowntree, Lilith F. Allen, Ruth R. Hagen, Hayley A. McQuilten, Ahmed Abdul Quadeer , et al. · 2025

Understanding host factors driving asymptomatic versus severe disease outcomes is of key importance if we are to control emerging and re-emerging viral infections. HLA-B*15:01 has been associated with asymptomatic SARS-CoV-2 infection in n…

Ultra‐Broadband Emission in Bi/Ge Co‐Doped Silica Glass and Fiber via Bismuth Coordination Engineering Open

Xin Li, Jinmin Tian, Chongyun Shao, Mengting Guo, Yinggang Chen , et al. · 2024

Bismuth (Bi) and Germanium (Ge) co‐doped silica glass and fiber, as advanced gain media with broadband near‐infrared (NIR) emission and amplification, have promise for extending communication bandwidth. However, efficiently modulating the …

Nonconserved epitopes dominate reverse preexisting T cell immunity in COVID-19 convalescents Open

Xin Wang, Jie Zhang, Maoshun Liu, Yuanyuan Guo, Peipei Guo , et al. · 2024

Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals Open

Jianing Zhang, Can Yue, Lin Yin, Jinmin Tian, Yuanyuan Guo , et al. · 2024

The individual HLA-related susceptibility to emerging viral diseases such as COVID-19 underscores the importance of understanding how HLA polymorphism influences peptide presentation and T cell recognition. Similar to HLA-A*0101, which is …

Long-lasting humoral and cellular memory immunity to vaccinia virus Tiantan provides pre-existing immunity against mpox virus in Chinese population Open

Min Li, Yaxin Guo, Yao Deng, Wenhui Gao, Baoying Huang , et al. · 2023

Investigating immune memory to vaccinia virus and pre-existing immunity to mpox virus (MPXV) among the population is crucial for the global response to this ongoing mpox epidemic. Blood was sampled from vaccinees inoculated with vaccinia v…

Inactivated vaccine fueled adaptive immune responses to Omicron in 2‐year COVID‐19 convalescents Open

Maoshun Liu, Jie Zhang, Lei Li, Jinmin Tian, Mengjie Yang , et al. · 2023

Over 3 years, humans have experienced multiple rounds of global transmission of SARS‐CoV‐2 and its variants. In addition, the widely used vaccines against SARS‐CoV‐2 involve multiple strategies of development and inoculation. Thus, the acq…

Choroidal Circulation in 8- to 30-Year-Old Chinese, Measured by SS-OCT/OCTA: Relations to Age, Axial Length, and Choroidal Thickness Open

Yuanyuan Wang, Mengqi Liu, Zhu Xie, Pengqi Wang, Xiang Li , et al. · 2023

Development of the choroidal medium- and large-sized vascular layers and choriocapillaris was different across patients aged 8 to 30 years old. Greater axial length was associated with attenuated choroidal circulation. Choroidal thickness …

Inactivated vaccine fueled adaptive immune responses to Omicron in 2-year COVID-19 convalescents Open

Maoshun Liu, Jie Zhang, Lei Li, Jianbo Zhan, Mengjie Yang , et al. · 2023

For nearly three years, humans have experienced multiple rounds of global transmission of SARS-CoV-2 and its variant strains. In addition, the widely used vaccines against SARS-CoV-2 involve multiple strategies of development and inoculati…

Seeing the T cell Immunity of SARS-CoV-2 and SARS-CoV: Believing the Epitope-Oriented Vaccines Open

Can Yue, Pengyan Wang, Jinmin Tian, George F. Gao, Kefang Liu , et al. · 2023

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at the end of 2019 stimulated vigorous research efforts in immunology and vaccinology. In addition to innate immune responses, both virus-specific humoral and ce…

Choroidal Blood Perfusion Could Predict the Sensitivity of Myopia Formation in Guinea Pigs Open

Yaozhen Yang, Mengxi Chen, Xinyuan Yao, Jiao Wang, Jiajia Shi , et al. · 2023

Immune response and homeostasis mechanism following administration of BBIBP-CorV SARS-CoV-2 inactivated vaccine Open

Jianhua Yin, Yingze Zhao, Fubaoqian Huang, Yunkai Yang, Yaling Huang , et al. · 2022

Sustained abnormality with recovery of COVID-19 convalescents: a 2-year follow-up study Open

Hao Lin, Xueyuan Liu, Heqiang Sun, Jie Zhang, Shaobo Dong , et al. · 2022

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Heterologous BBIBP-CorV/ZF2001 vaccination augments neutralization against SARS-CoV-2 variants: A preliminary observation Open

Yingze Zhao, Xin Zhao, Rong Zhang, Beiwei Ye, Xiaoju Yuan , et al. · 2022

High gain E-band amplification based on the low loss Bi/P co-doped silica fiber Open

Jinmin Tian, Mengting Guo, Fan Wang, Chunlei Yu, Lei Zhang , et al. · 2022

A home-made low loss Bi/P co-doped silica fiber was fabricated using the modified chemical vapor deposition (MCVD) technique combined with the solution doping method, where the background loss at 1550 nm was as low as 17 dB/km. We demonstr…

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