Jinrong Long
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View article: An Mpox Multi-Antigen-Tandem Bivalent mRNA Candidate Vaccine Effectively Protects Mice Against the Vaccinia Virus
An Mpox Multi-Antigen-Tandem Bivalent mRNA Candidate Vaccine Effectively Protects Mice Against the Vaccinia Virus Open
Background: Since the outbreak of mpox in 2022, the disease has spread rapidly worldwide and garnered significant public attention. Vaccination is regarded as an effective measure to prevent the spread of mpox. The success of the COVID-19 …
View article: Rapid identification of A29L antibodies based on mRNA immunization and high-throughput single B cell sequencing to detect Monkeypox virus
Rapid identification of A29L antibodies based on mRNA immunization and high-throughput single B cell sequencing to detect Monkeypox virus Open
With the large number of atypical cases in the mpox outbreak, which was classified as a global health emergency by the World Health Organization (WHO) on 23 July 2022, rapid diagnosis of mpox and diseases with similar symptoms to mpox such…
View article: Dendritic Cell‐Mimicking Nanoparticles Promote mRNA Delivery to Lymphoid Organs
Dendritic Cell‐Mimicking Nanoparticles Promote mRNA Delivery to Lymphoid Organs Open
Spleen and lymphoid organs are important targets for messenger RNA (mRNA) delivery in various applications. Current nanoparticle delivery methods rely on drainage to lymph nodes from intramuscular or subcutaneous injections. In difficult‐t…
View article: Novel Ionizable Lipid Nanoparticles for SARS‐CoV‐2 Omicron mRNA Delivery (Adv. Healthcare Mater. 13/2023)
Novel Ionizable Lipid Nanoparticles for SARS‐CoV‐2 Omicron mRNA Delivery (Adv. Healthcare Mater. 13/2023) Open
View article: Monkeypox virus quadrivalent mRNA vaccine induces immune response and protects against vaccinia virus
Monkeypox virus quadrivalent mRNA vaccine induces immune response and protects against vaccinia virus Open
View article: Novel Ionizable Lipid Nanoparticles for SARS‐CoV‐2 Omicron mRNA Delivery
Novel Ionizable Lipid Nanoparticles for SARS‐CoV‐2 Omicron mRNA Delivery Open
mRNA‐based therapy has emerged as the most promising nucleic acid therapy in the fight against COVID‐19. However, a safe and efficacious systemic delivery remains a challenge for mRNA therapy. Lipid nanoparticles (LNPs) are currently widel…
View article: Monkeypox virus quadrivalent mRNA vaccine induces antibody responses and cellular immunity and protects mice against Vaccinia virus
Monkeypox virus quadrivalent mRNA vaccine induces antibody responses and cellular immunity and protects mice against Vaccinia virus Open
There is an urgent need for efficient and safe vaccines against the monkeypox virus (MPXV) in response to the rapidly spreading monkeypox epidemic. In the age of COVID-19, mRNA vaccines have been highly successful and emerged as platforms …
View article: An mRNA vaccine with broad-spectrum neutralizing protection against Omicron variant sublineages BA.4/5 -included SARS-CoV-2
An mRNA vaccine with broad-spectrum neutralizing protection against Omicron variant sublineages BA.4/5 -included SARS-CoV-2 Open
View article: Rational preparation and application of a mRNA delivery system with cytidinyl/cationic lipid
Rational preparation and application of a mRNA delivery system with cytidinyl/cationic lipid Open