James Tang
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View article: Prognostic prediction nomogram of elderly patients with metastasis colon cancer and distant metastasis pattern: a SEER database analysis
Prognostic prediction nomogram of elderly patients with metastasis colon cancer and distant metastasis pattern: a SEER database analysis Open
This internally validated nomogram provides reliable individualized survival predictions for elderly patients. It offers a practical tool to assist clinicians in optimizing treatment strategies and risk stratification for this vulnerable p…
View article: Causal relationship between plasma lipidome and 6 types of cancer: A Mendelian randomization study
Causal relationship between plasma lipidome and 6 types of cancer: A Mendelian randomization study Open
This study explores the causal relationship between plasma lipidome and 6 common cancers using Mendelian randomization. Genome-wide association study data on 179 lipid species were used as exposures, with genome-wide association study data…
View article: Research on the Operation Optimization of Ground Source Heat Pump Heating System Based on Load Forecasting and Peak-Valley Electricity Prices
Research on the Operation Optimization of Ground Source Heat Pump Heating System Based on Load Forecasting and Peak-Valley Electricity Prices Open
View article: The Interaction Mechanism of Intramuscular Gene Delivery Materials with Cell Membranes
The Interaction Mechanism of Intramuscular Gene Delivery Materials with Cell Membranes Open
It has been confirmed that skeletal muscle cells have the capability to receive foreign plasmid DNA (pDNA) and express functional proteins. This provides a promisingly applicable strategy for safe, convenient, and economical gene therapy. …
View article: The Progress of Non-Viral Materials and Methods for Gene Delivery to Skeletal Muscle
The Progress of Non-Viral Materials and Methods for Gene Delivery to Skeletal Muscle Open
Since Jon A. Wolff found skeletal muscle cells being able to express foreign genes and Russell J. Mumper increased the gene transfection efficiency into the myocytes by adding polymers, skeletal muscles have become a potential gene deliver…
View article: Can nanoparticles and nano‒protein interactions bring a bright future for insulin delivery?
Can nanoparticles and nano‒protein interactions bring a bright future for insulin delivery? Open
View article: Regulation of RhoB Gene Expression during Tumorigenesis and Aging Process and Its Potential Applications in These Processes
Regulation of RhoB Gene Expression during Tumorigenesis and Aging Process and Its Potential Applications in These Processes Open
RhoB, a member of the Ras homolog gene family and GTPase, regulates intracellular signaling pathways by interfacing with epidermal growth factor receptor (EGFR), Ras, and phosphatidylinositol 3-kinase (PI3K)/Akt to modulate responses in ce…
View article: The proper strategy to compress and protect plasmid DNA in the Pluronic L64-electropulse system for enhanced intramuscular gene delivery
The proper strategy to compress and protect plasmid DNA in the Pluronic L64-electropulse system for enhanced intramuscular gene delivery Open
Intramuscular expression of functional proteins is a promising strategy for therapeutic purposes. Previously, we developed an intramuscular gene delivery method by combining Pluronic L64 and optimized electropulse, which is among the most …
View article: Bionic cartilage acellular matrix microspheres as a scaffold for engineering cartilage
Bionic cartilage acellular matrix microspheres as a scaffold for engineering cartilage Open
Bionic cartilage acellular matrix microspheres (BCAMMs) made from decelluarized bionic cartilage microspheres (BCMs).
View article: Microwave-assisted aqueous two-phase extraction of alkaloids from Radix Sophorae Tonkinensis with an ethanol/Na2HPO4 system: Process optimization, composition identification and quantification analysis
Microwave-assisted aqueous two-phase extraction of alkaloids from Radix Sophorae Tonkinensis with an ethanol/Na2HPO4 system: Process optimization, composition identification and quantification analysis Open
View article: Tailoring the Supramolecular Structure of Guanidinylated Pullulan toward Enhanced Genetic Photodynamic Therapy
Tailoring the Supramolecular Structure of Guanidinylated Pullulan toward Enhanced Genetic Photodynamic Therapy Open
In the progress of designing a gene carrier system, what is urgently needed is a balance of excellent safety and satisfactory efficiency. Herein, a straightforward and versatile synthesis of a cationic guanidine-decorated dendronized pullu…
View article: How's your back?
How's your back? Open
View article: Preparation, Characterization and Application of a Molecularly Imprinted Polymer for Selective Recognition of Sulpiride
Preparation, Characterization and Application of a Molecularly Imprinted Polymer for Selective Recognition of Sulpiride Open
A novel molecular imprinting polymer (MIP) was prepared by bulk polymerization using sulpiride as the template molecule, itaconic acid (ITA) as the functional monomer and ethylene glycol dimethacrylate (EGDMA) as the crosslinker. The forma…
View article: Tailoring the supramolecular structure of amphiphilic glycopolypeptide analogue toward liver targeted drug delivery systems
Tailoring the supramolecular structure of amphiphilic glycopolypeptide analogue toward liver targeted drug delivery systems Open
View article: Multi‐Responsive “Turn‐On” Nanocarriers for Efficient Site‐Specific Gene Delivery In Vitro and In Vivo
Multi‐Responsive “Turn‐On” Nanocarriers for Efficient Site‐Specific Gene Delivery In Vitro and In Vivo Open
Systemic gene delivery is a complicated and multistep process that confronts numerous biological barriers. It remains a formidable challenge to exploit a single gene carrier with multiple features to combat all obstacles collectively. Here…
View article: Synthesis of Electroneutralized Amphiphilic Copolymers with Peptide Dendrons for Intramuscular Gene Delivery
Synthesis of Electroneutralized Amphiphilic Copolymers with Peptide Dendrons for Intramuscular Gene Delivery Open
Intramuscular gene delivery materials are of great importance in plasmid-based gene therapy system, but there is limited information so far on how to design and synthesize them. A previous study showed that the peptide dendron-based triblo…
View article: Oral delivery of camptothecin using cyclodextrin/poly(anhydride) nanoparticles
Oral delivery of camptothecin using cyclodextrin/poly(anhydride) nanoparticles Open