Jing Wei
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View article: Associations of greenness and air pollution with leukocyte telomere length in Chinese children and adolescents
Associations of greenness and air pollution with leukocyte telomere length in Chinese children and adolescents Open
Evidence on the associations of greenness and air pollution with telomere length (TL) in children and adolescents remains scarce, and the potential role of air pollution in the greenness-TL association is unclear. We aimed to evaluate the …
View article: Transition of CELF2 PAS usage promotes recovery of refractory JDM through alternative splicing regulation of CTSB
Transition of CELF2 PAS usage promotes recovery of refractory JDM through alternative splicing regulation of CTSB Open
Alternative splicing (AS) and alternative polyadenylation (APA) are widespread in the immune system. However, their precise role in juvenile dermatomyositis (JDM) remains unclear. Based on the polyadenylation sequencing platform, we descri…
View article: Prenatal exposure to hyperglycemia and child growth trajectories in the first three years of life: a prospective birth cohort
Prenatal exposure to hyperglycemia and child growth trajectories in the first three years of life: a prospective birth cohort Open
Background Infants exposed to hyperglycemia in pregnancy (HIP) in utero are known to have higher risks of macrosomia at birth and obesity in adulthood, but little is known about how their growth patterns change over the first 3 years of li…
View article: PDX1 in early pregnancy is associated with decreased risks of gestational diabetes mellitus and adverse pregnancy outcomes
PDX1 in early pregnancy is associated with decreased risks of gestational diabetes mellitus and adverse pregnancy outcomes Open
Aim To investigate the association of pancreatic duodenal homeobox-1 (PDX1) in early pregnancy with the risks of gestational diabetes mellitus (GDM) and adverse pregnancy outcomes. Methods A total of 231 pregnant women were recruited at th…
View article: Evaluation of optic disc parameters, circumpapillary retinal nerve fiber layer (cpRNFL) and ganglion cell complex (GCC) in refractive error using SS-OCT: Magnification-corrected analysis
Evaluation of optic disc parameters, circumpapillary retinal nerve fiber layer (cpRNFL) and ganglion cell complex (GCC) in refractive error using SS-OCT: Magnification-corrected analysis Open
In the children and adolescents, after magnification correction, macular GCC thickness demonstrated a negative correlation with increasing myopic degree and AL elongation, while optic disc and rim areas showed positive correlations. Howeve…
View article: Evaluating the Utility of Hierarchical Multiple Regression and Quantile Regression in Determining Critical Factors for Success in Elite Men's Basketball
Evaluating the Utility of Hierarchical Multiple Regression and Quantile Regression in Determining Critical Factors for Success in Elite Men's Basketball Open
This research investigates the effectiveness of stratified multiple regression (MLR) and quantile regression (QR) in identifying the key performance indicators (KPIs) that impact the outcomes of elite men's basketball games. Using performa…
View article: Wide-field swept-source optical coherence tomography angiography (SS-OCTA) in the assessment of retinal vessel density and thickness in 4-to 16-year-old myopic children
Wide-field swept-source optical coherence tomography angiography (SS-OCTA) in the assessment of retinal vessel density and thickness in 4-to 16-year-old myopic children Open
The more severe the myopia, the longer the AL, the thinner the FRT in the perifovea, and the lower the VD in both the fovea and parafovea in children. In addition, DVD and ORT were more significantly correlated with AL, suggesting that the…
View article: Mechanism exploration and biomarker identification of glycemic deterioration in patients with diseases of the exocrine pancreas
Mechanism exploration and biomarker identification of glycemic deterioration in patients with diseases of the exocrine pancreas Open
The damage to the endocrine pancreas among patients with diseases of the exocrine pancreas (DP) leads to reduced glycemic deterioration, ultimately resulting in diabetes of the exocrine pancreas (DEP). The present research aims to investig…
View article: PSMA-targeted dendrimer as an efficient anticancer drug delivery vehicle for prostate cancer
PSMA-targeted dendrimer as an efficient anticancer drug delivery vehicle for prostate cancer Open
We present PD-CTT1298 nanoplatform as a versatile approach for selective systemic delivery of high payloads of potent chemotherapeutics to PSMA (+) prostate cancer, where dose related systemic side-effects are a major concern.
View article: Discovery of 2-deoxy glucose surfaced mixed layer dendrimer: a smart neuron targeted systemic drug delivery system for brain diseases
Discovery of 2-deoxy glucose surfaced mixed layer dendrimer: a smart neuron targeted systemic drug delivery system for brain diseases Open
The availability of non-invasive drug delivery systems capable of efficiently transporting bioactive molecules across the blood-brain barrier to specific cells at the injury site in the brain is currently limited. Delivering drugs to neuro…
View article: Association of MST1 in the First Trimester of Pregnancy with Gestational Diabetes Mellitus and Adverse Pregnancy Outcomes
Association of MST1 in the First Trimester of Pregnancy with Gestational Diabetes Mellitus and Adverse Pregnancy Outcomes Open
Elevated levels of MST1 in the first trimester of pregnancies are associated with increased risks of GDM and adverse pregnancy outcomes.
View article: Correlation between refractive errors and ocular biometric parameters in children and adolescents: a systematic review and meta-analysis
Correlation between refractive errors and ocular biometric parameters in children and adolescents: a systematic review and meta-analysis Open
Background Refractive errors are one of the most common ocular conditions among children and adolescents, with myopia showing an increasing prevalence and early onset in this population. Recent studies have identified a correlation between…
View article: MiR-100-5p transfected MSCs-derived exosomes can suppress NSCLC progression via PI3K-AKT-mTOR
MiR-100-5p transfected MSCs-derived exosomes can suppress NSCLC progression via PI3K-AKT-mTOR Open
Objectives Exosomes are highly implicated in lung cancer and are capable of transferring therapeutic miRNAs. Methods Database analysis was performed to screen the probable miRNA involved in non-small cell lung cancer (NSCLC). The levels of…
View article: The relationship between Axial Length and anterior segment biometry in Highly axial Myopic Children and Adolescents Aged 7 to 18 Years
The relationship between Axial Length and anterior segment biometry in Highly axial Myopic Children and Adolescents Aged 7 to 18 Years Open
Background The purpose of this study was to investigate the relationship between axial length(AL) and anterior segment biometry in highly axial myopic children and adolescents. Methods A cross-sectional study was conducted involving 366,27…
View article: CHAF1A promotes the proliferation and growth of epithelial ovarian cancer cells by affecting the phosphorylation of JAK2/STAT3 signaling pathway
CHAF1A promotes the proliferation and growth of epithelial ovarian cancer cells by affecting the phosphorylation of JAK2/STAT3 signaling pathway Open
The molecular mechanism of chromatin assembly factor 1 unit A (CHAF1A) promoting the proliferation and growth of epithelial ovarian cancer (EOC) cells hasn't been reported at present. In this study, recombinant CHAF1A siRNA/overexpression …
View article: Correlation Analysis of Staphylococcus aureus Drug Resistance and Virulence Factors with Blood Cell Counts and Coagulation Indexes
Correlation Analysis of Staphylococcus aureus Drug Resistance and Virulence Factors with Blood Cell Counts and Coagulation Indexes Open
Objective. The influence of different Staphylococcus aureus variants on blood cells and coagulation system was evaluated by investigating the carrying status of drug resistance genes and virulence genes of methicillin-resistantStaphylococc…
View article: sST2: A bridge between Sirt1/p53/p21 signal-induced senescence and TGF-β1/Smad2/3 regulation of cardiac fibrosis in mice viral myocarditis
sST2: A bridge between Sirt1/p53/p21 signal-induced senescence and TGF-β1/Smad2/3 regulation of cardiac fibrosis in mice viral myocarditis Open
Soluble interleukin 1 receptor-like 1 (sST2) is a novel predictor of poor outcomes, which is involved in inflammatory response and fibrosis of myocarditis. Cardiac fibrosis is a major cause of cardiovascular disease. Cellular senescence is…
View article: LINC01234 regulates microRNA-27b-5p to induce the migration, invasion and self-renewal of ovarian cancer stem cells through targeting SIRT5
LINC01234 regulates microRNA-27b-5p to induce the migration, invasion and self-renewal of ovarian cancer stem cells through targeting SIRT5 Open
LINC01234 has been suggested to correlate with the survival of ovarian cancer (OS), but its role in the properties of OC stem cells (OCSCs) has been rarely described. We aim to investigate the effect of LINC01234 on the differentiation and…
View article: LINC01234 regulates microRNA-27b-5p to induce the migration, invasion and self-renewal of ovarian cancer stem cells through targeting SIRT5
LINC01234 regulates microRNA-27b-5p to induce the migration, invasion and self-renewal of ovarian cancer stem cells through targeting SIRT5 Open
LINC01234 has been suggested to correlate with the survival of ovarian cancer (OS), but its role in the properties of OC stem cells (OCSCs) has been rarely described. We aim to investigate the effect of LINC01234 on the differentiation and…
View article: Association of Infant Physical Development and Rapid Growth With Pubertal Onset Among Girls in Rural China
Association of Infant Physical Development and Rapid Growth With Pubertal Onset Among Girls in Rural China Open
This study found that a higher weight-for-age z score and rapid weight gain during infancy, particularly from birth to 3 months of age, were associated with an increased likelihood of puberty onset in girls. These findings suggest that wei…
View article: Intrauterine double-balloon tamponade vs gauze packing in the management of placenta previa
Intrauterine double-balloon tamponade vs gauze packing in the management of placenta previa Open
Background: To evaluate the effectiveness and safety of a newly designed intrauterine double-balloon catheter to arrest postpartum hemorrhage (PPH) following cesarean delivery (CD) for placenta previa. Methods: We conducted an open-label, …