Jintu Chen
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View article: Protective effects of berbamine against arginase-1 deficiency-induced injury in human brain microvascular endothelial cells
Protective effects of berbamine against arginase-1 deficiency-induced injury in human brain microvascular endothelial cells Open
Endothelial cell dysfunction plays a crucial role in the early development of cerebral small vessel disease (CSVD). Arginase-1 (ARG1) is expressed in endothelial cells, and its deficiency may exacerbate cerebrovascular damage by increasing…
View article: Plasminogen Activator Inhibitor-1 4G/5G (rs1799889) Polymorphism in Chinese Patients with Diabetes Mellitus and Hypertension
Plasminogen Activator Inhibitor-1 4G/5G (rs1799889) Polymorphism in Chinese Patients with Diabetes Mellitus and Hypertension Open
The RT-PCR method can accurately identify the PAI-1 4G/5G genotype in different individuals. The PAI-1 4G/5G polymorphism may not be associated with genetic susceptibility to DM, HTN and DM+HTN, but differences in clinical characteristics …
View article: Downregulation of <i>SUMO2</i> inhibits hepatocellular carcinoma cell proliferation, migration and invasion
Downregulation of <i>SUMO2</i> inhibits hepatocellular carcinoma cell proliferation, migration and invasion Open
This study aimed to evaluate the prognostic value and biological function of small ubiquitin‐like modifier 2 ( SUMO2 ) in hepatocellular carcinoma (HCC). SUMO2 expression in HCC tissues was markedly higher than that in normal liver tissues…