Jinxiong Zhang
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View article: Contrastive learning-based multi-mechanism disentangled assessment for drug-drug interaction
Contrastive learning-based multi-mechanism disentangled assessment for drug-drug interaction Open
Background Polypharmacy’s ability to circumvent acquired resistance to single drug makes it a critical strategy for treating complex diseases. However, it inevitably carries risks of d rug- d rug i nteractions ( DDI s) that may alter pharm…
View article: Arithmetical Binary Decision Tree Traversals
Arithmetical Binary Decision Tree Traversals Open
This paper introduces a series of methods for traversing binary decision trees using arithmetic operations. We present a suite of binary tree traversal algorithms that leverage novel representation matrices to flatten the full binary tree …
View article: Decision Machines: Congruent Decision Trees
Decision Machines: Congruent Decision Trees Open
The decision tree recursively partitions the input space into regions and derives axis-aligned decision boundaries from data. Despite its simplicity and interpretability, decision trees lack parameterized representation, which makes it pro…
View article: Dive into Decision Trees and Forests: A Theoretical Demonstration
Dive into Decision Trees and Forests: A Theoretical Demonstration Open
Based on decision trees, many fields have arguably made tremendous progress in recent years. In simple words, decision trees use the strategy of "divide-and-conquer" to divide the complex problem on the dependency between input features an…
View article: Yet Another Representation of Binary Decision Trees: A Mathematical Demonstration
Yet Another Representation of Binary Decision Trees: A Mathematical Demonstration Open
A decision tree looks like a simple directed acyclic computational graph, where only the leaf nodes specify the output values and the non-terminals specify their tests or split conditions. From the numerical perspective, we express decisio…
View article: A method for identifying functional modules from the functionally-associated, significantly-co-expressed, and reliably-linked temporal dynamic PPI networks
A method for identifying functional modules from the functionally-associated, significantly-co-expressed, and reliably-linked temporal dynamic PPI networks Open
A protein functional module is an ensemble of proteins participating in a specific biological process. Proteins in a functional module temporally and dynamically interact to perform their biological function. According to biological behavi…
View article: Identifying Protein Complexes from Dynamic Temporal Interval Protein-Protein Interaction Networks
Identifying Protein Complexes from Dynamic Temporal Interval Protein-Protein Interaction Networks Open
Identification of protein complex is very important for revealing the underlying mechanism of biological processes. Many computational methods have been developed to identify protein complexes from static protein-protein interaction (PPI) …
View article: A method for identifying protein complexes with the features of joint co-localization and joint co-expression in static PPI networks
A method for identifying protein complexes with the features of joint co-localization and joint co-expression in static PPI networks Open