Jing Zhao
YOU?
Author Swipe
View article: Design, synthesis, and biological evaluation of central nervous system penetrant histone deacetylase inhibitors derived from imidazo[1,2-a] pyridine
Design, synthesis, and biological evaluation of central nervous system penetrant histone deacetylase inhibitors derived from imidazo[1,2-a] pyridine Open
View article: Machine learning model for HBsAg seroclearance after 48-week pegylated interferon therapy in inactive HBsAg carriers: a retrospective study
Machine learning model for HBsAg seroclearance after 48-week pegylated interferon therapy in inactive HBsAg carriers: a retrospective study Open
The RF-based model accurately predicts HBsAg clearance in IHC patients undergoing Peg-IFN therapy and offers a promising tool for early identification of candidates for individualized treatment strategies.
View article: Machine learning prediction of rapid HBsAg seroclearance at week 24 in inactive carriers treated with pegylated interferon
Machine learning prediction of rapid HBsAg seroclearance at week 24 in inactive carriers treated with pegylated interferon Open
Background and aim To identify predictive factors for rapid hepatitis B surface antigen (HBsAg) seroclearance at week 24 in inactive HBsAg carriers (IHC) receiving pegylated interferon alpha-2b (Peg-IFN) therapy, and to develop a machine l…
View article: Theta Burst Transcranial Ultrasound Stimulation of the Auditory Cortex Decreases Attention Activity
Theta Burst Transcranial Ultrasound Stimulation of the Auditory Cortex Decreases Attention Activity Open
Background: Transcranial ultrasound stimulation (TUS) is a new technique used for non-invasive brain stimulation. Theta burst TUS (tbTUS) as a repetitive TUS protocol can increase human motor cortical excitability, but its neuromodulatory …
View article: Dexmedetomidine pretreatment improves postsurgical delay in neurocognitive recovery in aged mice by inhibiting hippocampal microglial activation via activation of cholinergic anti-inflammatory pathways
Dexmedetomidine pretreatment improves postsurgical delay in neurocognitive recovery in aged mice by inhibiting hippocampal microglial activation via activation of cholinergic anti-inflammatory pathways Open
View article: Search for Cardiomyocyte-Specific Targeting Sequences and Their Application in the Treatment of Myocardial Infarction
Search for Cardiomyocyte-Specific Targeting Sequences and Their Application in the Treatment of Myocardial Infarction Open
To find cardiomyocyte-specific targeting sequences, transform existing cardiac targeting peptides (CTPs) to the gene level, use this as a basis to improve cardiomyocyte-specific delivery systems, and explore new promising directions for th…
View article: The relationship between perceived organizational support and insomnia in psychiatric nurses in China: the mediating role of psychological capital
The relationship between perceived organizational support and insomnia in psychiatric nurses in China: the mediating role of psychological capital Open
View article: Human immunodeficiency virus accelerates brain aging and disrupts the trajectory of glymphatic clearance in aging brain
Human immunodeficiency virus accelerates brain aging and disrupts the trajectory of glymphatic clearance in aging brain Open
Introduction Existing evidence indicates that HIV enters the nervous system in the early days of infection. However, the involvement of HIV in the pathogenesis of key biological aspects of the brain, such as glymphatic clearance and brain …
View article: Ventricular volume adjustment of brain regions depicts brain changes associated with HIV infection and aging better than intracranial volume adjustment
Ventricular volume adjustment of brain regions depicts brain changes associated with HIV infection and aging better than intracranial volume adjustment Open
Introduction While the adjustment of intracranial volume (ICV) is reported to have a significant influence in the outcomes of the analyses of brain structural measures, our study offers a paradigm shift, positing that adjusting for lateral…
View article: Early atypical MRI findings in a pediatric patient with Neuro-Behçet’s disease
Early atypical MRI findings in a pediatric patient with Neuro-Behçet’s disease Open
View article: Preliminary experience of combined dual plasma molecular adsorption system and plasma exchange in pediatric acute liver failure: a retrospective case series
Preliminary experience of combined dual plasma molecular adsorption system and plasma exchange in pediatric acute liver failure: a retrospective case series Open
View article: A Comparative Investigation on Clinical Characteristics in Pediatric Obstructive Sleep Apnea Based on Two Distinct Guidelines
A Comparative Investigation on Clinical Characteristics in Pediatric Obstructive Sleep Apnea Based on Two Distinct Guidelines Open
The 2020 guideline has advantages in assessing the clinical characteristics of children with OSA, especially for verbal function, and is worthy of clinical promotion and application.
View article: Is the Effect of Chronological Age on Postoperative Complications Related to Comorbidity Burden? A Population Study of Revision Total Knee Arthroplasty Patients
Is the Effect of Chronological Age on Postoperative Complications Related to Comorbidity Burden? A Population Study of Revision Total Knee Arthroplasty Patients Open
Background: The number of revision total knee arthroplasty (TKA) procedures continues to rise. Both advanced chronological age and comorbidity burden are associated with poor surgical outcomes. However, the question remains whether these t…
View article: IL-27 Modulates Mesenchymal Stem Cell Immunoplasticity for Enhanced Lupus Nephritis Therapy via the JAK1–STAT1–IDO Axis and Tryptophan Metabolic Orchestration
IL-27 Modulates Mesenchymal Stem Cell Immunoplasticity for Enhanced Lupus Nephritis Therapy via the JAK1–STAT1–IDO Axis and Tryptophan Metabolic Orchestration Open
Lupus nephritis is recognized as a common and severe complication of systemic lupus erythematosus, without an optimal therapeutic strategy currently available. While mesenchymal stem cells (MSCs) hold therapeutic promise, their efficacy va…
View article: RSEIU: A recommendation algorithm for shopping based on explicit and implicit feedback of user
RSEIU: A recommendation algorithm for shopping based on explicit and implicit feedback of user Open
Business websites typically employ recommendation systems to process large amounts of information. The lack of behavioral data for new users leads to the system’s inability to make recommendations for them, which is known as the cold-start…
View article: The pitfalls and challenges in the diagnosis and treatment of patients with carotid near-occlusion: a narrative review
The pitfalls and challenges in the diagnosis and treatment of patients with carotid near-occlusion: a narrative review Open
The diagnosis of CNO based on feature interpretation necessitates a cautious approach. It is imperative to conduct large prospective clinical trials to identify the optimal treatment for patients with various types of CNO.
View article: Primary Sjögren’s syndrome complicated by renal tubular acidosis and acute bilateral uveitis: a case report and literature review
Primary Sjögren’s syndrome complicated by renal tubular acidosis and acute bilateral uveitis: a case report and literature review Open
Primary Sjögren’s syndrome (pSS) is an autoimmune disease that can cause gland dysfunction, leading to dry mouth and dry eyes as the main clinical manifestations. In addition, pSS may affect the gastrointestinal tract, skin, lungs, kidneys…
View article: Prognostic analysis of destroyed-lung patients with preoperative massive hemoptysis: a 20-year retrospective study
Prognostic analysis of destroyed-lung patients with preoperative massive hemoptysis: a 20-year retrospective study Open
DL patients with massive hemoptysis had greater rate of invasive respiratory support therapy and postoperative complications. Extensive lesion removal, preoperative anaemia, severe intraoperative bleeding associated with recent postoperati…
View article: Analysis of clinical characteristics of different types of lung function impaiement in TDL patients
Analysis of clinical characteristics of different types of lung function impaiement in TDL patients Open
Aim The clinical characteristics associated with pulmonary function decline in patients with Tuberculosis-destroyed lung (TDL) remain uncertain. We categorize them based on the pattern of pulmonary function impairment, distinguishing betwe…
View article: The global burden of cataracts and its attributable risk factors in 204 countries and territories: a systematic analysis of the global burden of disease study
The global burden of cataracts and its attributable risk factors in 204 countries and territories: a systematic analysis of the global burden of disease study Open
Introduction The global distribution and trends in the attributable burden of cataract risk have rarely been systematically explored. To guide the development of targeted and accurate cataract screening and treatment strategies, we analyze…
View article: [Neonatal cervical chondromesenchymal hamartoma: a case report and literature review].
[Neonatal cervical chondromesenchymal hamartoma: a case report and literature review]. Open
Cartilage mesenchyme hamartoma originates from the mesoderm and contains a blend of interstitium and cartilage, which is mostly benign tumor and is a non-neoplastic cartilage lesion with self-limiting hyperplasia. This article repo…
View article: [The relationship between birth weight and obstructive sleep apnea in children].
[The relationship between birth weight and obstructive sleep apnea in children]. Open
Objective:To study the relationship between children's birth weight and obstructive sleep apnea（OSA）. Methods:The sleep data and birth information of children who underwent polysomnography in the Department of Otorhinolaryngo…
View article: Management of Pediatric Laryngotracheal Trauma
Management of Pediatric Laryngotracheal Trauma Open
To summarize and describe the clinical presentations, diagnostic approaches, and airway management techniques in children with laryngotracheal (LT) trauma. Methods: We retrospectively reviewed clinical data related to LT trauma diagnosed a…
View article: Value of preoperative evaluation of FEV1 in patients with destroyed lung undergoing pneumonectomy - a 20-year real-world study
Value of preoperative evaluation of FEV1 in patients with destroyed lung undergoing pneumonectomy - a 20-year real-world study Open
Background Clinical guidelines recommend a preoperative forced expiratory volume in one second (FEV 1 ) of > 2 L as an indication for left or right pneumonectomy. This study compares the safety and long-term prognosis of pneumonectomy for …
View article: Probing bundle-wise abnormalities in patients infected with human immunodeficiency virus using fixel-based analysis: new insights into neurocognitive impairments
Probing bundle-wise abnormalities in patients infected with human immunodeficiency virus using fixel-based analysis: new insights into neurocognitive impairments Open
Background: Changes in white matter (WM) underlie the neurocognitive damages induced by a human immunodeficiency virus (HIV) infection. This study aimed to examine using a bundle-associated fixel-based analysis (FBA) pipeline for investiga…
View article: The conscious processing of emotion in depression disorder: a meta-analysis of neuroimaging studies
The conscious processing of emotion in depression disorder: a meta-analysis of neuroimaging studies Open
Background Depression is generally accompanied by a disturbed conscious processing of emotion, which manifests as a negative bias to facial/voice emotion information and a decreased accuracy in emotion recognition tasks. Several studies ha…
View article: Commentary: Effects of rhythmic auditory stimulation on motor function and balance ability in stroke: a systematic review and meta-analysis of clinical randomized controlled studies
Commentary: Effects of rhythmic auditory stimulation on motor function and balance ability in stroke: a systematic review and meta-analysis of clinical randomized controlled studies Open
GENERAL COMMENTARY article Front. Neurosci., 05 May 2023Sec. Neurodegeneration Volume 17 - 2023 | https://doi.org/10.3389/fnins.2023.1174540
View article: Serum HBsAg and HBcrAg is associated with inflammation in HBeAg-positive chronic hepatitis B patients
Serum HBsAg and HBcrAg is associated with inflammation in HBeAg-positive chronic hepatitis B patients Open
Backgrounds & aims Liver inflammation is the main risk factor for developing liver fibrosis, cirrhosis, and even hepatocellular carcinoma in chronic hepatitis B (CHB) patients. To replace biopsy, additional non-invasive biomarkers to d…
View article: Correction for: Bacopaside I ameliorates cognitive impairment in APP/PS1 mice via immune-mediated clearance of β-amyloid
Correction for: Bacopaside I ameliorates cognitive impairment in APP/PS1 mice via immune-mediated clearance of β-amyloid Open
View article: Factors Related to Plasma Homocysteine Concentration in Young Adults: A Retrospective Study Based on Checkup Populations
Factors Related to Plasma Homocysteine Concentration in Young Adults: A Retrospective Study Based on Checkup Populations Open
The distribution profile of plasma homocysteine (Hcy) in young adults and its related factors are not well understood. We performed a generalized estimating equations (GEE) analysis for plasma-Hcy-correlated factors in 2436 young adults, a…