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View article: Viral Vaccines as an Alternative to Antimicrobials: A Perspective from Swine Veterinarians on Challenges, Opportunities, and Future Directions
Viral Vaccines as an Alternative to Antimicrobials: A Perspective from Swine Veterinarians on Challenges, Opportunities, and Future Directions Open
Antimicrobial resistance (AMR) is an increasing concern in food animal production. In swine herds, viral infections often lead to secondary bacterial disease and higher antimicrobial use (AMU). This study describes how U.S. swine veterinar…
View article: Viral Vaccines as an Alternative to Antimicrobials: A Perspective from Swine Veterinarians on Challenges, Opportunities, and Future Directions
Viral Vaccines as an Alternative to Antimicrobials: A Perspective from Swine Veterinarians on Challenges, Opportunities, and Future Directions Open
Antimicrobial resistance (AMR) is a growing global threat driven by the overuse of antibiotics, especially in livestock. In the swine industry, viral diseases often lead to secondary bacterial infections, which increases the need for wides…
View article: Challenges and Opportunities of Bacterial Vaccines as Alternatives to Antimicrobials in Swine Health Management: Insights from U.S. Veterinarians
Challenges and Opportunities of Bacterial Vaccines as Alternatives to Antimicrobials in Swine Health Management: Insights from U.S. Veterinarians Open
Antimicrobial resistance (AMR) is a significant global health concern, and the use of antibiotics in livestock, including swine production, is a major contributor. Vaccines offer a promising alternative for controlling bacterial infections…
View article: Challenges and Opportunities of Bacterial Vaccines as Alternatives to Antimicrobials in Swine Health Management: Insights from U.S. Veterinarians
Challenges and Opportunities of Bacterial Vaccines as Alternatives to Antimicrobials in Swine Health Management: Insights from U.S. Veterinarians Open
Antimicrobial resistance (AMR) is a significant global health concern, and the use of antibiotics in livestock, including swine production, is a major contributor. Vaccines offer a promising alternative for controlling bacterial infections…
View article: Kansas State University: Impactful research advancing African swine fever virus prevention, control, and response
Kansas State University: Impactful research advancing African swine fever virus prevention, control, and response Open
View article: Genetic Profiles of Ten African Swine Fever Virus Strains from Outbreaks in Select Provinces of Luzon, Visayas, and Mindanao, Philippines, Between 2021 and 2023
Genetic Profiles of Ten African Swine Fever Virus Strains from Outbreaks in Select Provinces of Luzon, Visayas, and Mindanao, Philippines, Between 2021 and 2023 Open
An African Swine Fever (ASF) outbreak was first recorded in the Philippines in July 2019. Since then, the disease has spread across provinces in Luzon, Visayas, and Mindanao, causing severe economic consequences for the country’s swine ind…
View article: Genetic Profiles of Ten African Swine Fever Virus Strains from Outbreaks in Select Provinces of Luzon, Visayas, and Mindanao, Philippines Between 2021 and 2023
Genetic Profiles of Ten African Swine Fever Virus Strains from Outbreaks in Select Provinces of Luzon, Visayas, and Mindanao, Philippines Between 2021 and 2023 Open
African Swine Fever (ASF) outbreak was first recorded in the Philippines in July 2019. Since then, the disease has spread across provinces in Luzon, Visayas, and Mindanao causing severe economic consequences for the country’s swine industr…
View article: Specific Detection of African Swine Fever Virus Variants: Novel Quadplex Real-Time PCR Assay with Internal Control
Specific Detection of African Swine Fever Virus Variants: Novel Quadplex Real-Time PCR Assay with Internal Control Open
African swine fever (ASF), a highly contagious and lethal viral disease, continues to devastate the global swine industry. The emergence of ASF virus (ASFV) variants with varying genomic deletions poses significant challenges for ASF contr…
View article: Toward a rapid, sensitive, user-friendly, field-deployable artificial intelligence tool for enhancing African swine fever diagnosis and reporting
Toward a rapid, sensitive, user-friendly, field-deployable artificial intelligence tool for enhancing African swine fever diagnosis and reporting Open
Objective African swine fever (ASF) is a lethal and highly contagious transboundary animal disease with the potential for rapid international spread. Lateral flow assays (LFAs) are sometimes hard to read by the inexperienced user, mainly d…
View article: Sensitive and Specific Detection of African Swine Fever Virus Variants: A Novel Quadplex Real-Time PCR Assay with Internal Control
Sensitive and Specific Detection of African Swine Fever Virus Variants: A Novel Quadplex Real-Time PCR Assay with Internal Control Open
African swine fever (ASF), a highly contagious and lethal viral disease, continues to devastate the global swine industry. The emergence of ASF virus (ASFV) variants with varying genomic deletions poses significant challenges to ASF contro…
View article: Development and evaluation of two rapid lateral flow assays for on-site detection of African swine fever virus
Development and evaluation of two rapid lateral flow assays for on-site detection of African swine fever virus Open
Introduction African swine fever (ASF) is a lethal and highly contagious transboundary animal disease with the potential for rapid international spread. In the absence of a widely available and definitively proven vaccine, rapid and early …
View article: A Non-Hemadsorbing Live-Attenuated Virus Vaccine Candidate Protects Pigs against the Contemporary Pandemic Genotype II African Swine Fever Virus
A Non-Hemadsorbing Live-Attenuated Virus Vaccine Candidate Protects Pigs against the Contemporary Pandemic Genotype II African Swine Fever Virus Open
African swine fever (ASF) is a highly contagious and severe hemorrhagic transboundary swine viral disease with up to a 100% mortality rate, which leads to a tremendous socio-economic loss worldwide. The lack of safe and efficacious ASF vac…
View article: Editorial: Advances and insights in the diagnosis of viral infections and vaccines development in animals
Editorial: Advances and insights in the diagnosis of viral infections and vaccines development in animals Open
Editorial: Advances and insights in the diagnosis of viral infections and vaccines development in animals
View article: A Non-Haemadsorbing Live-Attenuated Virus Vaccine Candidate Protects Pigs Against Contemporary Pandemic Genotype Ii African Swine Fever Virus
A Non-Haemadsorbing Live-Attenuated Virus Vaccine Candidate Protects Pigs Against Contemporary Pandemic Genotype Ii African Swine Fever Virus Open
View article: 2023 International African Swine Fever Workshop: Critical Issues That Need to Be Addressed for ASF Control
2023 International African Swine Fever Workshop: Critical Issues That Need to Be Addressed for ASF Control Open
The 2023 International African Swine Fever Workshop (IASFW) took place in Beijing, China, on 18–20 September 2023. It was jointly organized by the U.S.-China Center for Animal Health (USCCAH) at Kansas State University (KSU) and the Chines…
View article: A Cell-Adapted Live-Attenuated Vaccine Candidate Protects Pigs against the Homologous Strain VNUA-ASFV-05L1, a Representative Strain of the Contemporary Pandemic African Swine Fever Virus
A Cell-Adapted Live-Attenuated Vaccine Candidate Protects Pigs against the Homologous Strain VNUA-ASFV-05L1, a Representative Strain of the Contemporary Pandemic African Swine Fever Virus Open
African swine fever (ASF) is a lethal and highly contagious transboundary animal disease with the potential for rapid international spread. Currently, there is no ASF vaccine commercially available. All infected animals must be isolated an…
View article: A Cell-Adapted Live-Attenuated Vaccine Protects Pigs against the Contemporary Pandemic African Swine Fever Virus
A Cell-Adapted Live-Attenuated Vaccine Protects Pigs against the Contemporary Pandemic African Swine Fever Virus Open
African swine fever (ASF) is a lethal and highly contagious transboundary animal disease with the potential for rapid international spread. Currently, there is no ASF vaccine commercially available. All infected animals must be isolated an…
View article: An easy method to generate recombinant pseudorabies virus expressing the capsid protein of Porcine circovirus type 2d
An easy method to generate recombinant pseudorabies virus expressing the capsid protein of Porcine circovirus type 2d Open
Introduction Homologous recombination is an effective way to generate recombinant viruses for vaccine research such as pseudorabies virus (PRV) and adenovirus. Its efficiency can be affected by the integrity of viral genome and the lineari…
View article: Development of Porcine Monoclonal Antibodies with In Vitro Neutralizing Activity against Classical Swine Fever Virus from C-Strain E2-Specific Single B Cells
Development of Porcine Monoclonal Antibodies with In Vitro Neutralizing Activity against Classical Swine Fever Virus from C-Strain E2-Specific Single B Cells Open
Neutralizing antibodies (nAbs) can be used before or after infection to prevent or treat viral diseases. However, there are few efficacious nAbs against classical swine fever virus (CSFV) that have been produced, especially the porcine-ori…
View article: Characterization of monoclonal antibodies that specifically differentiate field isolates from vaccine strains of classical swine fever virus
Characterization of monoclonal antibodies that specifically differentiate field isolates from vaccine strains of classical swine fever virus Open
Classical swine fever virus (CSFV) is a major animal pathogen threatening the global pork industry. To date, numerous anti-CSFV monoclonal antibodies (mAbs) and their recognizing epitopes have been reported. However, few mAbs were systemat…
View article: A Novel Competitive ELISA for Specifically Measuring and Differentiating Immune Responses to Classical Swine Fever C-Strain Vaccine in Pigs
A Novel Competitive ELISA for Specifically Measuring and Differentiating Immune Responses to Classical Swine Fever C-Strain Vaccine in Pigs Open
Classical swine fever can be controlled effectively by vaccination with C-strain vaccine. In this study, we developed a novel competitive enzyme-linked immunosorbent assay (cELISA) based on a C-strain Erns specific monoclonal antibody (mAb…
View article: Development of a Self-Emulsifying Adjuvant for Use in Swine Vaccines
Development of a Self-Emulsifying Adjuvant for Use in Swine Vaccines Open
Emulsion-based adjuvants are commonly used in animal vaccine formulations for several reasons including affordability, stability, and efficacy in inducing disease-protecting immune responses. Here we report a novel, cost-effective, stable,…
View article: Building public-private partnerships to advance global veterinary medical education: the US-China Joint DVM Program
Building public-private partnerships to advance global veterinary medical education: the US-China Joint DVM Program Open
View article: Genome Sequence of a Virulent African Swine Fever Virus Isolated in 2020 from a Domestic Pig in Northern Vietnam
Genome Sequence of a Virulent African Swine Fever Virus Isolated in 2020 from a Domestic Pig in Northern Vietnam Open
This study reports the genome sequence of an isolated African swine fever (ASF) virus (VNUA-ASFV-05L1/HaNam) obtained at the fourth passage on pulmonary alveolar macrophages. The virus was isolated during a typical acute ASF outbreak in pi…
View article: Of pigs and men: the best-laid plans for prevention and control of swine fevers
Of pigs and men: the best-laid plans for prevention and control of swine fevers Open
View article: Recent Advances in the Diagnosis of Classical Swine Fever and Future Perspectives
Recent Advances in the Diagnosis of Classical Swine Fever and Future Perspectives Open
Classical swine fever (CSF) is a highly contagious viral disease of pigs, including wild boar. It is regarded as one of the major problems in the pig industry as it is still endemic in many regions of the world and has the potential to cau…
View article: Synergistic China–US Ecological Research is Essential for Global Emerging Infectious Disease Preparedness
Synergistic China–US Ecological Research is Essential for Global Emerging Infectious Disease Preparedness Open
View article: Deletion of CD2-like gene from the genome of African swine fever virus strain Georgia does not attenuate virulence in swine
Deletion of CD2-like gene from the genome of African swine fever virus strain Georgia does not attenuate virulence in swine Open
The CD2-like African swine fever virus (ASFV) gene 8DR, (also known as EP402R) encodes for a structural transmembrane glycoprotein that has been shown to mediate hemadsorption and be involved in host immunomodulation as well as the inducti…
View article: A neutralizing monoclonal antibody-based competitive ELISA for classical swine fever C-strain post–vaccination monitoring
A neutralizing monoclonal antibody-based competitive ELISA for classical swine fever C-strain post–vaccination monitoring Open
View article: A neutralizing monoclonal antibody-based competitive ELISA for classical swine fever C-strain post–vaccination monitoring
A neutralizing monoclonal antibody-based competitive ELISA for classical swine fever C-strain post–vaccination monitoring Open
Background: Virus neutralization test (VNT) is widely used for serological survey of classical swine fever (CSF) and efficacy evaluation of CSF vaccines. However, VNT is a time consuming procedure that requires cell culture and live virus …