Jishuai Zhao
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View article: Gypenoside XLIX inhibiting PI3K/AKT/FOXO1 signaling pathway mediated neuronal mitochondrial autophagy to improve patients with ischemic stroke
Gypenoside XLIX inhibiting PI3K/AKT/FOXO1 signaling pathway mediated neuronal mitochondrial autophagy to improve patients with ischemic stroke Open
Introduction Ischemic stroke is a leading cause of mortality and disability worldwide, with limited therapeutic options and high rates of recurrence. Mitochondrial dysfunction plays a critical role in neuronal injury during ischemia-reperf…
View article: Correlation Analysis between Serum NLRP1 Inflammasome and Depression in Acute Stage of Stroke
Correlation Analysis between Serum NLRP1 Inflammasome and Depression in Acute Stage of Stroke Open
Introduction: The aim of this study was to investigate the correlation between serum NLRP1 inflammasome level and depressive state in acute stage of stroke. Methods: A total of 102 patients with acute stroke who were hospitalized for the f…
View article: Identification of Mitochondrial and Succinylation Modification-Related Gene Signature in Ischemic Stroke
Identification of Mitochondrial and Succinylation Modification-Related Gene Signature in Ischemic Stroke Open
Ischemic stroke (IS) is a leading cause of death and disability worldwide, often associated with immune dysregulation, mitochondrial dysfunction, and altered protein succinylation. This study aimed to identify mitochondrial and succinylati…
View article: Mechanism of Gynostemmae Pentaphylli Herba in the treatment of ischemic stroke based on network pharmacology and molecular docking.
Mechanism of Gynostemmae Pentaphylli Herba in the treatment of ischemic stroke based on network pharmacology and molecular docking. Open
Gynostemmae Pentaphylli Herba may play a role in treating ischemic stroke by affecting various pathways through its active ingredients such as Ruvoside_qt, quercetin, 3'-methyleriodictyol, Spinasterol and CLR.