Jayanti Mukherjee
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View article: Structural and mechanistic insights into herpesvirus helicase–primase and its therapeutic inhibitors
Structural and mechanistic insights into herpesvirus helicase–primase and its therapeutic inhibitors Open
The herpes simplex virus (HSV) helicase-primase (HP) complex is a promising anti-herpes therapeutic target. However, progress in developing highly effective small-molecule HP inhibitors (HPIs) for the treatment of genital herpes has been h…
View article: Botox Treatment: A Comprehensive Review
Botox Treatment: A Comprehensive Review Open
An exotoxin called botulinum toxin, or Botox, is isolated from Clostridium botulinum. It prevents the cholinergic nerve end plates from releasing acetylcholine, which causes the innervated muscles or glands to become inactive. Botox has pr…
View article: Formulation and Evaluation of Imiquimod Emulgel for Treatment of Common Warts
Formulation and Evaluation of Imiquimod Emulgel for Treatment of Common Warts Open
The objective of the present work is to develop and optimize emulgel system for epidermal and dermal delivery of drug which delivers the drug in local sites more efficiently than cream and other gel preparations. The drug imiquimod is loca…
View article: Analytical Method Development and Validation of Posaconazole by QbD Approach
Analytical Method Development and Validation of Posaconazole by QbD Approach Open
Quality by design (QbD) is modern and systematic approach for product development and quality of pharmaceuticals. In this concept of QbD it is essential to define desire product performance profile, analytical target Profile and identify c…
View article: Formulation and Evaluation of Orodispersible Tablets of Etoricoxib Using Hibiscus Rosa Sinesis Muscillage as Natural Super Disintegrant
Formulation and Evaluation of Orodispersible Tablets of Etoricoxib Using Hibiscus Rosa Sinesis Muscillage as Natural Super Disintegrant Open
The aim of the study is to formulate orodispersible tablet of Etoricoxib for the pain management of rheumatoid arthritis and to improve the efficacy and patient compliance.In the present work, orodispersible tablets of Etoricoxib were prep…
View article: Formulation and Evaluation of Transdermal Patch of Thiochochicoside
Formulation and Evaluation of Transdermal Patch of Thiochochicoside Open
The aim of the study is to formulate and evaluate transdermal patches of Thiocholchicoside In the present study, matrix type were prepared by moulding techniques. This mode of drug delivery is more beneficial for chronic disorders such as …
View article: To Evaluate the Stability of Carbopol 934 based Transdermal Gel of Paracetamol Nanocapsules
To Evaluate the Stability of Carbopol 934 based Transdermal Gel of Paracetamol Nanocapsules Open
The nanocapsules were prepared by the interfacial deposition technique proposed in the year 1989. The required quantity of the drug and benzyl benzoate were mixed and added dropwise in the organic phase containing the polymer PLGA dissolve…
View article: Delays in treatment intensification with oral antidiabetic drugs and risk of microvascular and macrovascular events in patients with poor glycaemic control: <scp>A</scp> n individual patient simulation study
Delays in treatment intensification with oral antidiabetic drugs and risk of microvascular and macrovascular events in patients with poor glycaemic control: <span>A</span> n individual patient simulation study Open
Aims To use the Archimedes model to estimate the consequences of delays in oral antidiabetic drug ( OAD ) treatment intensification on glycaemic control and long‐term outcomes at 5 and 20 years. Materials and methods Using real‐world data,…
View article: Health-related quality-of-life implications of cardiovascular events in individuals with type 2 diabetes mellitus: A subanalysis from the Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus (SAVOR)-TIMI 53 trial
Health-related quality-of-life implications of cardiovascular events in individuals with type 2 diabetes mellitus: A subanalysis from the Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus (SAVOR)-TIMI 53 trial Open
BMS/AZ.
View article: The 2016 oxide electronic materials and oxide interfaces roadmap
The 2016 oxide electronic materials and oxide interfaces roadmap Open
International audience
View article: Association Between Weight Change, Clinical Outcomes, and Health Care Costs in Patients with Type 2 Diabetes
Association Between Weight Change, Clinical Outcomes, and Health Care Costs in Patients with Type 2 Diabetes Open
This study was sponsored by AstraZeneca and Bristol-Myers Squibb. Truven Health Analytics received funding from Bristol-Myers Squibb and AstraZeneca to conduct this study. Mukherjee is an employee of Bristol-Myers Squibb. Bell and Sternhuf…
View article: Cardiovascular Risk Factor Targets and Cardiovascular Disease Event Risk in Diabetes: A Pooling Project of the Atherosclerosis Risk in Communities Study, Multi-Ethnic Study of Atherosclerosis, and Jackson Heart Study
Cardiovascular Risk Factor Targets and Cardiovascular Disease Event Risk in Diabetes: A Pooling Project of the Atherosclerosis Risk in Communities Study, Multi-Ethnic Study of Atherosclerosis, and Jackson Heart Study Open
OBJECTIVE Controlling cardiovascular disease (CVD) risk factors in diabetes mellitus (DM) reduces the number of CVD events, but the effects of multifactorial risk factor control are not well quantified. We examined whether being at targets…