Jitendra Shandilya
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View article: Clinicopathological and Immunogenetic Characterization in 8 Patients with Familial Hemophagocytic Lymphohistiocytosis Type 2: A Study from North India with Literature Review
Clinicopathological and Immunogenetic Characterization in 8 Patients with Familial Hemophagocytic Lymphohistiocytosis Type 2: A Study from North India with Literature Review Open
Familial hemophagocytic lymphohistiocytosis type 2 (FHL2) is the commonest cause of familial hemophagocytic lymphohistiocytosis (FHLH). In this retrospective study, we analyzed 8 patients with a genetic diagnosis of FHL2 and then examined …
View article: Markers of T Lymphocyte Activation in Children With Kawasaki Disease: An Experimental Study From North India
Markers of T Lymphocyte Activation in Children With Kawasaki Disease: An Experimental Study From North India Open
Background The exact pathogenesis of Kawasaki disease (KD) is unknown despite extensive research in the area. Several studies have also implicated CD8 + T lymphocytes in the pathogenesis of KD. However, studies on the activation status of …
View article: Myriad complement defects in atypical hemolytic uremic syndrome and short term outcome in the absence of eculizumab.
Myriad complement defects in atypical hemolytic uremic syndrome and short term outcome in the absence of eculizumab. Open
An amiss complement pathway can cause atypical hemolytic uremic syndrome (aHUS) with microangiopathic hemolytic anemia, thrombocytopenia and acute kidney injury. An observational study to understand complement abnormalities and outcome amo…
View article: Monocyte subsets and their activation markers in Kawasaki disease – A Study from a Tertiary care Center in North India
Monocyte subsets and their activation markers in Kawasaki disease – A Study from a Tertiary care Center in North India Open
Background : Kawasaki disease (KD) is a common childhood vasculitis and autopsy studies have shown monocyte infiltration in affected blood vessels. Role of monocyte subsets and their activation status in KD have not been completely explore…
View article: Skewed TCR Alpha, but not Beta, Gene Rearrangements and Lymphoma Associated with a Pathogenic TRAC Variant
Skewed TCR Alpha, but not Beta, Gene Rearrangements and Lymphoma Associated with a Pathogenic TRAC Variant Open
View article: Monocyte platelet aggregates in children with Kawasaki disease- a preliminary study from a tertiary care centre in North-West India
Monocyte platelet aggregates in children with Kawasaki disease- a preliminary study from a tertiary care centre in North-West India Open
View article: Clinical, Immunological, and Molecular Profile of Chronic Granulomatous Disease: A Multi-Centric Study of 236 Patients From India
Clinical, Immunological, and Molecular Profile of Chronic Granulomatous Disease: A Multi-Centric Study of 236 Patients From India Open
Background Chronic granulomatous disease (CGD) is an inherited defect in phagocytic respiratory burst that results in severe and life-threatening infections in affected children. Single center studies from India have shown that proportion …
View article: Clinical and Genetic Profile of X-Linked Agammaglobulinemia: A Multicenter Experience From India
Clinical and Genetic Profile of X-Linked Agammaglobulinemia: A Multicenter Experience From India Open
Background There is paucity of literature on XLA from developing countries. Herein we report the clinical and molecular profile and outcome in a multicenter cohort of patients with XLA from India. Methods Data on XLA from all regional cent…
View article: Monocyte Platelet Aggregates in Children with Kawasaki Disease- a Preliminary Study from a Tertiary Care Centre in North-West India
Monocyte Platelet Aggregates in Children with Kawasaki Disease- a Preliminary Study from a Tertiary Care Centre in North-West India Open
Background: Platelet activation is an integral part of pathogenesis of Kawasaki disease (KD). However, there is paucity of literature on flow-cytometry based assessment of platelet activation in KD. We aimed to analyse monocyte-platelet ag…
View article: Monocyte Platelet Aggregates in Children with Kawasaki Disease- a Preliminary Study from a Tertiary Care Centre in North-West India
Monocyte Platelet Aggregates in Children with Kawasaki Disease- a Preliminary Study from a Tertiary Care Centre in North-West India Open
Background:Platelet activation is an integral part of pathogenesis of Kawasaki disease (KD). However, there is paucity of literature on flow-cytometry based assessment of platelet activation in KD. We aimed to analyse monocyte-platelet agg…
View article: Flow Cytometry for Diagnosis of Primary Immune Deficiencies—A Tertiary Center Experience From North India
Flow Cytometry for Diagnosis of Primary Immune Deficiencies—A Tertiary Center Experience From North India Open
Flow cytometry has emerged as a useful technology that has facilitated our understanding of the human immune system. Primary immune deficiency disorders (PIDDs) are a heterogeneous group of inherited disorders affecting the immune system. …
View article: Recent advances in chronic granulomatous disease
Recent advances in chronic granulomatous disease Open
Chronic granulomatous disease (CGD) is an inherited defect of phagocyte function due to defective NADPH oxidase. Patients with CGD are not able to effectively clear the infections because of the defect in the phagocyte production of oxygen…
View article: THU0510 NEUTROPHIL FUNCTION IN PEDIATRIC SYSTEMIC LUPUS ERYTHEMATOSUS
THU0510 NEUTROPHIL FUNCTION IN PEDIATRIC SYSTEMIC LUPUS ERYTHEMATOSUS Open
View article: Low Expression of Leucocyte Associated Immunoglobulin Like Receptor-1 (LAIR-1/CD305) in a Cohort of Pediatric Acute Lymphoblastic Leukemia Cases
Low Expression of Leucocyte Associated Immunoglobulin Like Receptor-1 (LAIR-1/CD305) in a Cohort of Pediatric Acute Lymphoblastic Leukemia Cases Open
Background: Immunophenotypic markers can play significant role in prognostic assessment for different cancers and leukocyte-associated Ig-like receptor (LAIR-1) is a recently identified inhibitory immuno-receptor. Methods: We measured LAIR…
View article: O19 Perforin & granzyme expression: role of natural killer cell cytotoxicity in acute phase of Kawasaki disease
O19 Perforin & granzyme expression: role of natural killer cell cytotoxicity in acute phase of Kawasaki disease Open
View article: Flowcytometric expression of LAIR-1 inhibitory immune-receptor in pediatric acute lymphoblastic leukemia cases does not correlate with standard risk factors and minimal residual disease
Flowcytometric expression of LAIR-1 inhibitory immune-receptor in pediatric acute lymphoblastic leukemia cases does not correlate with standard risk factors and minimal residual disease Open