Jiufu Qin
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View article: Harnessing synthetic biology for tetraterpenoid astaxanthin production: Recent advances and challenges
Harnessing synthetic biology for tetraterpenoid astaxanthin production: Recent advances and challenges Open
View article: Overexpression of arginase gene CAR1 renders yeast Saccharomyces cerevisiae acetic acid tolerance
Overexpression of arginase gene CAR1 renders yeast Saccharomyces cerevisiae acetic acid tolerance Open
Acetic acid is a common inhibitor present in lignocellulose hydrolysate, which inhibits the ethanol production by yeast strains. Therefore, the cellulosic ethanol industry requires yeast strains that can tolerate acetic acid stress. Here w…
View article: Enzyme engineering for functional lipids synthesis: recent advance and perspective
Enzyme engineering for functional lipids synthesis: recent advance and perspective Open
View article: Increasing gene dosage and chaperones co-expression facilitate the efficient dextranase expression in Pichia pastoris
Increasing gene dosage and chaperones co-expression facilitate the efficient dextranase expression in Pichia pastoris Open
Dextranase (DEX) is an important hydrolase in the food industry, which can degrade the dextran into low-molecular-weight polysaccharides. However, its commercial applications are limited by ineffective heterologous recombination system. He…
View article: Modulation of gut flore by dietary fibers from Pyrus bretschneideri Rehd.: Evaluation of fermentation characteristics using a colonic in vitro fermentation model
Modulation of gut flore by dietary fibers from Pyrus bretschneideri Rehd.: Evaluation of fermentation characteristics using a colonic in vitro fermentation model Open
Nutrients such as dietary fiber in Pyrus bretschneideri Rehd. (PBR), which is mainly produced on the Tibetan Plateau, can be used as a fermentable carbon source for microorganisms. However, the mechanisms by which different carbon sources …
View article: Exogenous fatty acid renders the improved salt tolerance in Zygosaccharomyces rouxii by altering lipid metabolism
Exogenous fatty acid renders the improved salt tolerance in Zygosaccharomyces rouxii by altering lipid metabolism Open
The yeast Zygosaccharomyces rouxii has long been used in traditional fermented food whose high quality and specific flavor are closely connected with this yeast. We previously showed that the salt tolerance of Z. rouxii could further be re…
View article: Directed evolution driving the generation of an efficient keratinase variant to facilitate the feather degradation
Directed evolution driving the generation of an efficient keratinase variant to facilitate the feather degradation Open
Keratinases can specifically degrade keratins, which widely exist in hair, horns, claws and human skin. There is a great interest in developing keratinase to manage keratin waste generated by the poultry industry and reusing keratin produc…
View article: Engineered Reversal of Function in Glycolytic Yeast Promoters
Engineered Reversal of Function in Glycolytic Yeast Promoters Open
Promoters are key components of cell factory design, allowing precise expression of genes in a heterologous pathway. Several commonly used promoters in yeast cell factories belong to glycolytic genes, highly expressed in actively growing y…
View article: Engineering the protein secretory pathway of <i>Saccharomyces cerevisiae</i> enables improved protein production
Engineering the protein secretory pathway of <i>Saccharomyces cerevisiae</i> enables improved protein production Open
Significance Recombinant proteins production by cell factories for medical and industrial use is one of the most prominent achievements in the modern biotech industry. It is constantly necessary to explore the underlying mechanisms of prot…
View article: Production of fatty acid-derived oleochemicals and biofuels by synthetic yeast cell factories
Production of fatty acid-derived oleochemicals and biofuels by synthetic yeast cell factories Open
View article: Modular pathway rewiring of Saccharomyces cerevisiae enables high-level production of L-ornithine
Modular pathway rewiring of Saccharomyces cerevisiae enables high-level production of L-ornithine Open