Jing Cui
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View article: Association Between Sleep Duration, Screen-Based Sedentary Time, and Weight Status Among Chinese Adolescents
Association Between Sleep Duration, Screen-Based Sedentary Time, and Weight Status Among Chinese Adolescents Open
Objectives: The aim of this study was to examine the association between sleep duration, screen-based sedentary time, and overweight/obesity prevalence among Chinese adolescents. Methods: A cross-sectional analysis was conducted on 6174 ad…
View article: EFNA5 as an Oocyte-Derived Factor Enhances Developmental Competence by Modulating Oxidative Stress, Inflammation, and Apoptosis During In Vitro Maturation
EFNA5 as an Oocyte-Derived Factor Enhances Developmental Competence by Modulating Oxidative Stress, Inflammation, and Apoptosis During In Vitro Maturation Open
In vitro maturation (IVM) of oocytes remains suboptimal due to oxidative stress and disrupted cumulus–oocyte communication. Oocyte-derived factors (ODFs) are key mediators of this crosstalk and crucial for oocyte competence. Here, we provi…
View article: Granzyme B contributes to subretinal fibrosis in neovascular age-related macular degeneration by modulating inflammation and epithelial-mesenchymal transition
Granzyme B contributes to subretinal fibrosis in neovascular age-related macular degeneration by modulating inflammation and epithelial-mesenchymal transition Open
View article: Affection of Exposure to Per- and Polyfluoroalkyl Substances Mixture with Peripheral Blood Cells in Colorectal Cancer Patients
Affection of Exposure to Per- and Polyfluoroalkyl Substances Mixture with Peripheral Blood Cells in Colorectal Cancer Patients Open
As extensively used chemicals in various consumer products, per-and perfluoroalkyl substances (PFASs) are pervasive and could significantly risk human health after environmental exposure. In recent years, studies have reported the associat…
View article: EFNA5 as an Oocyte-Derived Factor Enhances Developmental Competence by Modulating Oxidative Stress, Inflammation, and Apoptosis During In Vitro Maturation
EFNA5 as an Oocyte-Derived Factor Enhances Developmental Competence by Modulating Oxidative Stress, Inflammation, and Apoptosis During In Vitro Maturation Open
In vitro maturation (IVM) of oocytes remains suboptimal due to oxidative stress and disrupted cumulus–oocyte communication. Oocyte-derived factors (ODFs) are key mediators of this crosstalk and crucial for oocyte competence. Here, we provi…
View article: The impact of anesthesia methods on early postoperative cognitive function in Moyamoya disease patients after vascular bypass surgery
The impact of anesthesia methods on early postoperative cognitive function in Moyamoya disease patients after vascular bypass surgery Open
Moyamoya disease (MMD) patients often experience cognitive dysfunction following vascular bypass surgery, with anesthesia potentially influencing recovery. This study aims to evaluate the effects of IVA and combined intravenous and inhalat…
View article: Novel modulation of T effector memory cells-expressing CD45RA by prednisone in inoperable advanced type B thymoma patients
Novel modulation of T effector memory cells-expressing CD45RA by prednisone in inoperable advanced type B thymoma patients Open
View article: Predicting survival and immune status of breast cancer patients based on prognostic features related to PANoptosis
Predicting survival and immune status of breast cancer patients based on prognostic features related to PANoptosis Open
The current research introduces a novel model for BRCA prognosis analysis but also provides a fresh perspective on BRCA treatment strategies.
View article: Cellular crosstalk in organotypic vasculature: mechanisms of diabetic cardiorenal complications and SGLT2i responses
Cellular crosstalk in organotypic vasculature: mechanisms of diabetic cardiorenal complications and SGLT2i responses Open
View article: Rapid and precise identification of cervicothoracic necrotizing fasciitis caused by Prevotella and Streptococcus constellatus by using Nanopore sequencing technology: a case report
Rapid and precise identification of cervicothoracic necrotizing fasciitis caused by Prevotella and Streptococcus constellatus by using Nanopore sequencing technology: a case report Open
Introduction Cervicothoracic necrotizing fasciitis (CNF) is one form of necrotizing soft-tissue infections, which could lead to patient demise during short course. Therefore, early recognition and immediate treatment contribute to promisin…
View article: Dual roles of CD11b+CD33+HLA-DR-/lowCD14- myeloid-derived suppressor cells with a granulocytic morphology following allogeneic hematopoietic stem cell transplantation: from inflammation promoters to immune suppressors within 90 days
Dual roles of CD11b+CD33+HLA-DR-/lowCD14- myeloid-derived suppressor cells with a granulocytic morphology following allogeneic hematopoietic stem cell transplantation: from inflammation promoters to immune suppressors within 90 days Open
Introduction Granulocytic myeloid-derived suppressor cells (G-MDSCs) show fast recovery following allogeneic hematopoietic stem cell transplantation (allo-HSCT) constituting the major part of peripheral blood in the early phase. Although G…
View article: Correction: Granzyme B degrades extracellular matrix and promotes inflammation and choroidal neovascularization
Correction: Granzyme B degrades extracellular matrix and promotes inflammation and choroidal neovascularization Open
View article: Granzyme B degrades extracellular matrix and promotes inflammation and choroidal neovascularization
Granzyme B degrades extracellular matrix and promotes inflammation and choroidal neovascularization Open
View article: GIMAP5 deficiency reveals a mammalian ceramide-driven longevity assurance pathway
GIMAP5 deficiency reveals a mammalian ceramide-driven longevity assurance pathway Open
View article: Vascular and extravascular localization of Aβ in Alzheimer’s retina
Vascular and extravascular localization of Aβ in Alzheimer’s retina Open
Background Recent in vivo and ex vivo studies have demonstrated retinal vasculopathy may be associated with Alzheimer’s disease (AD). We investigated amyloid beta (Ab) localization relative to vessels in wholemount retinas from AD and cont…
View article: Retinal Manifestations of Alzheimer’s Disease: MicroRNAs and Microglial Phenotypes
Retinal Manifestations of Alzheimer’s Disease: MicroRNAs and Microglial Phenotypes Open
Background As part of the CNS, retina is a promising site for studying Alzheimer’s disease (AD) and developing potential biomarkers for accessible screening and early diagnosis. Our group has previously investigated retinal amyloid beta (A…
View article: Ligand-independent activation of platelet-derived growth factor receptor β promotes vitreous-induced contraction of retinal pigment epithelial cells
Ligand-independent activation of platelet-derived growth factor receptor β promotes vitreous-induced contraction of retinal pigment epithelial cells Open
Background Epiretinal membranes in patients with proliferative vitreoretinopathy (PVR) consist of extracellular matrix and a number of cell types including retinal pigment epithelial (RPE) cells and fibroblasts, whose contraction causes re…
View article: Could microRNAs expressed in the tear fluids predict underlying molecular changes associated with Alzheimer’s disease (AD) at an early stage?
Could microRNAs expressed in the tear fluids predict underlying molecular changes associated with Alzheimer’s disease (AD) at an early stage? Open
Background Non‐coding small microRNAs (miRNAs) are a large family of post‐transcriptional regulators of gene expression and recent advances demonstrate their utility as disease biomarkers. Altered miRNA expression levels associated with AD…
View article: Fuziline Ameliorates Glucose and Lipid Metabolism by Activating Beta Adrenergic Receptors to Stimulate Thermogenesis
Fuziline Ameliorates Glucose and Lipid Metabolism by Activating Beta Adrenergic Receptors to Stimulate Thermogenesis Open
Radix aconiti carmichaeli is a widely used traditional Chinese medicine that has been found to be effective in treating cardiovascular diseases and metabolic disorders. Patients with these diseases often experience a heat generation disord…
View article: MicroRNAs in tear fluids predict underlying molecular changes associated with Alzheimer’s disease
MicroRNAs in tear fluids predict underlying molecular changes associated with Alzheimer’s disease Open
Extracellular circulating microRNAs (miRNAs) have been discussed as potential biomarkers for Alzheimer’s disease (AD) diagnosis. As the retina is a part of the CNS, we hypothesize that miRNAs expression levels in the brain, particularly ne…
View article: Granzyme B Contributes to Choroidal Neovascularization and Age-Related Macular Degeneration Through Proteolysis of Thrombospondin-1
Granzyme B Contributes to Choroidal Neovascularization and Age-Related Macular Degeneration Through Proteolysis of Thrombospondin-1 Open
View article: Ligand-independent Activation of Platelet-derived Growth Factor Receptor β promotes contraction of retinal pigment epithelial cells
Ligand-independent Activation of Platelet-derived Growth Factor Receptor β promotes contraction of retinal pigment epithelial cells Open
Background Epiretinal membranes in patients with proliferative vitreoretinopathy (PVR) consist of extracellular matrix and a number of cell types including retinal pigment epithelial (RPE) cells and fibroblasts, whose contraction causes re…
View article: The “Hand as Foot” teaching method in atlanto-axial subluxation
The “Hand as Foot” teaching method in atlanto-axial subluxation Open
View article: Synovial chondromatosis
Synovial chondromatosis Open
View article: Müller cell degeneration and microglial dysfunction in the Alzheimer’s retina
Müller cell degeneration and microglial dysfunction in the Alzheimer’s retina Open
View article: Early B cell factor 4 modulates FAS-mediated apoptosis and promotes cytotoxic function in human immune cells
Early B cell factor 4 modulates FAS-mediated apoptosis and promotes cytotoxic function in human immune cells Open
Apoptosis is a genetically regulated program of cell death that plays a key role in immune disease processes. We identified EBF4, a little-studied member of the early B cell factor (EBF) family of transcription factors, in a whole-genome C…
View article: Vibrio vulnificus necrotizing fasciitis with sepsis presenting with pain in the lower legs in winter: a case report
Vibrio vulnificus necrotizing fasciitis with sepsis presenting with pain in the lower legs in winter: a case report Open
Background Vibrio vulnificus infections develop rapidly and are associated with a high mortality rate. The rates of diagnosis and treatment are directly associated with mortality. Case presentation We describe an unusual case of a 61-year-…
View article: Monosodium Glutamate-Induced Mouse Model With Unique Diabetic Retinal Neuropathy Features and Artificial Intelligence Techniques for Quantitative Evaluation
Monosodium Glutamate-Induced Mouse Model With Unique Diabetic Retinal Neuropathy Features and Artificial Intelligence Techniques for Quantitative Evaluation Open
Objective To establish an artificial intelligence-based method to quantitatively evaluate subtle pathological changes in retinal nerve cells and synapses in monosodium glutamate (MSG) mice and provide an effective animal model and techniqu…
View article: Targeting selenoprotein H in the nucleolus suppresses tumors and metastases by Isovalerylspiramycin I
Targeting selenoprotein H in the nucleolus suppresses tumors and metastases by Isovalerylspiramycin I Open
Background Compared to normal cells, cancer cells exhibit a higher level of oxidative stress, which primes key cellular and metabolic pathways and thereby increases their resilience under oxidative stress. This higher level of oxidative st…
View article: A novel mode of action for COX‐2 inhibition: Targeting ATPase domain of HSP90 induces ubiquitin degradation of new client protein COX‐2
A novel mode of action for COX‐2 inhibition: Targeting ATPase domain of HSP90 induces ubiquitin degradation of new client protein COX‐2 Open
Dear Editor, Cyclooxygenase 2 (COX-2) is the main target of nonsteroidal anti-inflammatory drugs (NSAIDs),1 and it is rapidly expressed in response to extracellular factor stimulation like lipopolysaccharide (LPS) in mouse monocyte macroph…