Jo-Anne O. Shepard
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View article: <i>RadioGraphics</i> Update: The 10 Pillars of Lung Cancer Screening—Rationale and Logistics of a Lung Cancer Screening Program
<i>RadioGraphics</i> Update: The 10 Pillars of Lung Cancer Screening—Rationale and Logistics of a Lung Cancer Screening Program Open
Editor's Note.-RadioGraphics Update articles supplement or update information found in full-length articles previously published in RadioGraphics. These updates, written by at least one author of the previous article, …
View article: Role of sex in lung cancer risk prediction based on single low-dose chest computed tomography
Role of sex in lung cancer risk prediction based on single low-dose chest computed tomography Open
A validated open-source deep-learning algorithm called Sybil can accurately predict long-term lung cancer risk from a single low-dose chest computed tomography (LDCT). However, Sybil was trained on a majority-male cohort. Use of artificial…
View article: Validation of a Deep Learning–Based Model to Predict Lung Cancer Risk Using Chest Radiographs and Electronic Medical Record Data
Validation of a Deep Learning–Based Model to Predict Lung Cancer Risk Using Chest Radiographs and Electronic Medical Record Data Open
Importance Lung cancer screening with chest computed tomography (CT) prevents lung cancer death; however, fewer than 5% of eligible Americans are screened. CXR-LC, an open-source deep learning tool that estimates lung cancer risk from exis…
View article: E-Cigarette Use, Small Airway Fibrosis, and Constrictive Bronchiolitis
E-Cigarette Use, Small Airway Fibrosis, and Constrictive Bronchiolitis Open
After thorough evaluation for other potential etiologies, vaping was considered to be the most likely common causal etiology for all patients due to the temporal association of symptomatic chronic lung disease with e-cigarette use and part…
View article: Incidence of Radiation Therapy Among Patients Enrolled in a Multidisciplinary Pulmonary Nodule and Lung Cancer Screening Clinic
Incidence of Radiation Therapy Among Patients Enrolled in a Multidisciplinary Pulmonary Nodule and Lung Cancer Screening Clinic Open
In this unique prospective cohort, 1 in 4 patients with screen-detected pulmonary nodules requiring intervention were treated with stereotactic body radiation therapy. This finding highlights the role of radiation therapy in a lung cancer …
View article: Preoperative CT-guided Fiducial Marker Placement for Surgical Localization of Pulmonary Nodules
Preoperative CT-guided Fiducial Marker Placement for Surgical Localization of Pulmonary Nodules Open
The CT-guided fiducial marker placement of pulmonary nodules was safe, effective, and resulted in a low surgical localization failure rate.Keywords: CT, Percutaneous, Thorax, Lung.
View article: Characteristics and Outcomes of Lung Cancers Detected on Low-Dose Lung Cancer Screening CT
Characteristics and Outcomes of Lung Cancers Detected on Low-Dose Lung Cancer Screening CT Open
Background: Lung cancer screening (LCS) with low-dose CT (LDCT) was implemented in the United States following the National Lung Screening Trial (NLST). The real-world benefits of implementing LCS are yet to be determined with outcome-orie…
View article: Artificial intelligence-based vessel suppression for detection of sub-solid nodules in lung cancer screening computed tomography
Artificial intelligence-based vessel suppression for detection of sub-solid nodules in lung cancer screening computed tomography Open
AI-VS improved the detection and classification of SSN into GGN and PSN on LDCT of the chest for the two radiologist (R1 and R2) readers.
View article: Multi-Radiologist User Study for Artificial Intelligence-Guided Grading of COVID-19 Lung Disease Severity on Chest Radiographs
Multi-Radiologist User Study for Artificial Intelligence-Guided Grading of COVID-19 Lung Disease Severity on Chest Radiographs Open
View article: Lung cancer screening eligibility and use with low‐dose computed tomography: Results from the 2018 Behavioral Risk Factor Surveillance System cross‐sectional survey
Lung cancer screening eligibility and use with low‐dose computed tomography: Results from the 2018 Behavioral Risk Factor Surveillance System cross‐sectional survey Open
Background In randomized controlled trials, lung cancer screening with low‐dose chest computed tomography (LCS) has been reported to reduce lung cancer mortality. Although initial studies suggested that only approximately 5% of eligible pa…
View article: Operational Challenges of a Low-Dose CT Lung Cancer Screening Program During the Coronavirus Disease 2019 Pandemic
Operational Challenges of a Low-Dose CT Lung Cancer Screening Program During the Coronavirus Disease 2019 Pandemic Open
View article: Implementation of the Radiological Society of North America Expert Consensus Guidelines on Reporting Chest CT Findings Related to COVID-19: A Multireader Performance Study
Implementation of the Radiological Society of North America Expert Consensus Guidelines on Reporting Chest CT Findings Related to COVID-19: A Multireader Performance Study Open
The "typical appearance" category for COVID-19 CT reporting has an average sensitivity of 86% and specificity rate of 80%. There is reasonable interreader agreement and good reproducibility across various levels of experience.
View article: Case 25-2020: A 47-Year-Old Woman with a Lung Mass
Case 25-2020: A 47-Year-Old Woman with a Lung Mass Open
A Woman with a Lung Mass A 47-year-old woman presented early during the Covid-19 pandemic with cough and shortness of breath. Radiography revealed a rounded mass in the right lower lobe. Computed t...
View article: Pulmonary Vascular Manifestations of COVID-19 Pneumonia
Pulmonary Vascular Manifestations of COVID-19 Pneumonia Open
Pulmonary vascular abnormalities such as vessel enlargement and regional mosaic perfusion patterns are common in COVID-19 pneumonia. Perfusion abnormalities are also frequently observed at DECT in COVID-19 pneumonia and may suggest an unde…
View article: Direct and indirect CT imaging features of esophago-airway fistula in adults
Direct and indirect CT imaging features of esophago-airway fistula in adults Open
CT plays an essential role in both the primary and secondary evaluation of adult EAF resulting from both malignant and benign etiologies. CT may be the first diagnostic exam to suggest and detect the presence of EAF and may precede clinica…
View article: Case 17-2020: A 68-Year-Old Man with Covid-19 and Acute Kidney Injury
Case 17-2020: A 68-Year-Old Man with Covid-19 and Acute Kidney Injury Open
A Man with Covid-19 and Acute Kidney Injury A 68-year-old man was admitted to the hospital with fever, shortness of breath, and acute kidney injury. Testing of a nasopharyngeal swab for SARS-CoV-2 ...
View article: Hypoxaemia related to COVID-19: vascular and perfusion abnormalities on dual-energy CT
Hypoxaemia related to COVID-19: vascular and perfusion abnormalities on dual-energy CT Open
View article: Integrated, Multidisciplinary Management of Pulmonary Nodules Can Streamline Care and Improve Adherence to Recommendations
Integrated, Multidisciplinary Management of Pulmonary Nodules Can Streamline Care and Improve Adherence to Recommendations Open
Every year millions of pulmonary nodules are discovered incidentally and through lung cancer screening programs. Management of these nodules is often suboptimal, with low follow-up rates and poor provider understanding of management approa…
View article: Multidisciplinary selection of pulmonary nodules for surgical resection: Diagnostic results and long-term outcomes
Multidisciplinary selection of pulmonary nodules for surgical resection: Diagnostic results and long-term outcomes Open
View article: Feasibility and accuracy of CT-guided percutaneous needle biopsy of cavitary pulmonary lesions
Feasibility and accuracy of CT-guided percutaneous needle biopsy of cavitary pulmonary lesions Open
PTNB of cavitary lesions provides high accuracy, sensitivity, and specificity for both malignancy and infection and has an acceptable complication rate. Wall thickness at the biopsy site, lesion in lower lobe, and malignancy were significa…
View article: Deploying Clinical Process Improvement Strategies to Reduce Motion Artifacts and Expiratory Phase Scanning in Chest CT
Deploying Clinical Process Improvement Strategies to Reduce Motion Artifacts and Expiratory Phase Scanning in Chest CT Open
View article: Safety and Success of Repeat Lung Needle Biopsies in Patients with Epidermal Growth Factor Receptor-Mutant Lung Cancer
Safety and Success of Repeat Lung Needle Biopsies in Patients with Epidermal Growth Factor Receptor-Mutant Lung Cancer Open
Background Postprogression repeat biopsies are critical in caring for patients with lung cancer with epidermal growth factor receptor (EGFR) mutations. However, hesitation about invasive procedures persists. We assessed safety and tissue a…
View article: Non-Diagnostic CT-Guided Percutaneous Needle Biopsy of the Lung: Predictive Factors and Final Diagnoses
Non-Diagnostic CT-Guided Percutaneous Needle Biopsy of the Lung: Predictive Factors and Final Diagnoses Open
The predictive factors for a non-diagnostic biopsy were lesion size ≤ 15 mm, needle tract traversing emphysema, introducer needle outside the lesion, procedure time > 60 minutes, and presence of alveolar hemorrhage. Thirty-six percent of t…
View article: Determining malignancy in CT guided fine needle aspirate biopsy of subsolid lung nodules: Is core biopsy necessary?
Determining malignancy in CT guided fine needle aspirate biopsy of subsolid lung nodules: Is core biopsy necessary? Open
View article: Feasibility of Perioperative Micro–Computed Tomography of Human Lung Cancer Specimens: A Pilot Study
Feasibility of Perioperative Micro–Computed Tomography of Human Lung Cancer Specimens: A Pilot Study Open
Context.— Lesion localization during intraoperative frozen section of lung resection specimens can be challenging. Imaging could aid lesion localization while enabling 3-dimensional specimen analysis. Objective.— To assess the feasibility …
View article: Process improvement for reducing side discrepancies in radiology reports
Process improvement for reducing side discrepancies in radiology reports Open
Background Laterality errors in radiology reports can lead to serious errors in management. Purpose To reduce errors related to side discrepancies in radiology reports from thoracic imaging by 50% over a six-month period with education and…
View article: Clinical Utility of Rapid <i>EGFR</i> Genotyping in Advanced Lung Cancer
Clinical Utility of Rapid <i>EGFR</i> Genotyping in Advanced Lung Cancer Open
Purpose Targeted therapy is the cornerstone of treatment of advanced EGFR-mutant non–small-cell lung cancer (NSCLC). Next-generation sequencing (NGS), the preferred method for genotyping, typically requires several weeks. Here, we assessed…
View article: CT texture analysis of histologically proven benign and malignant lung lesions
CT texture analysis of histologically proven benign and malignant lung lesions Open
The purpose of our study was to determine accuracy of CT texture analysis (CTTA) for differentiating benign from malignant pulmonary nodules, and well-differentiated from poorly differentiated lung cancers, with histology as the standard o…
View article: Fluorodeoxyglucose positron emission tomography for detection of tumor recurrence following radiofrequency ablation in retrospective cohort of stage I lung cancer
Fluorodeoxyglucose positron emission tomography for detection of tumor recurrence following radiofrequency ablation in retrospective cohort of stage I lung cancer Open
A pattern of focally intense and increasing FDG PET uptake has high sensitivity and specificity for detecting recurrent lung cancer following RFA. Surveillance after RFA should include a contrast enhanced diagnostic CT at 1 month to diagno…
View article: Imaging of the trachea
Imaging of the trachea Open
Numerous benign and malignant tracheal diseases may affect the trachea primarily and secondarily. While the posterior anterior (PA) and lateral chest radiograph is the conventional study for initial evaluation of the trachea and central ai…