Joan Blanco
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View article: The Utility of Sperm DNA Fragmentation as a Diagnostic Tool for Male Infertility and Its Predictive Value for Assisted Reproductive Technology Outcomes
The Utility of Sperm DNA Fragmentation as a Diagnostic Tool for Male Infertility and Its Predictive Value for Assisted Reproductive Technology Outcomes Open
Standard semen parameters remain the cornerstone of male infertility evaluation, though they often poorly reflect the likelihood of success in assisted reproductive technology (ART). This study evaluates sperm DNA fragmentation (SDF) as a …
View article: Unraveling the Intricacies of the Seminal Microbiome and Its Impact on Human Fertility
Unraveling the Intricacies of the Seminal Microbiome and Its Impact on Human Fertility Open
Although the microbial communities from seminal fluid were an unexplored field some decades ago, their characteristics and potential roles are gradually coming to light. Therefore, a complex and specific microbiome population with commensa…
View article: The courtship choreography of homologous chromosomes: timing and mechanisms of DSB-independent pairing
The courtship choreography of homologous chromosomes: timing and mechanisms of DSB-independent pairing Open
Meiosis involves deep changes in the spatial organisation and interactions of chromosomes enabling the two primary functions of this process: increasing genetic diversity and reducing ploidy level. These two functions are ensured by crucia…
View article: A transcriptomic insight into the human sperm microbiome through next-generation sequencing
A transcriptomic insight into the human sperm microbiome through next-generation sequencing Open
The purpose of this study is to provide novel information through Next Generation Sequencing (NGS) for the characterization of viral and bacterial RNA cargo of human sperm cells from healthy fertile donors. For this, RNA-seq raw data of po…
View article: A transcriptomic insight into the human sperm microbiome through next-generation sequencing
A transcriptomic insight into the human sperm microbiome through next-generation sequencing Open
The purpose of this study is to provide novel information through Next Generation Sequencing (NGS) for the characterization of viral and bacterial RNA cargo of human sperm cells from healthy fertile donors. For this, RNA-seq raw data of po…
View article: Time to match; when do homologous chromosomes become closer?
Time to match; when do homologous chromosomes become closer? Open
View article: Clonal heterogeneity and rates of specific chromosome gains are risk predictors in childhood high‐hyperdiploid B‐cell acute lymphoblastic leukemia
Clonal heterogeneity and rates of specific chromosome gains are risk predictors in childhood high‐hyperdiploid B‐cell acute lymphoblastic leukemia Open
B‐cell acute lymphoblastic leukemia (B‐ALL) is the commonest childhood cancer. High hyperdiploidy (HHD) identifies the most frequent cytogenetic subgroup in childhood B‐ALL. Although hyperdiploidy represents an important prognostic factor …
View article: The RNA content of human sperm reflects prior events in spermatogenesis and potential post-fertilization effects
The RNA content of human sperm reflects prior events in spermatogenesis and potential post-fertilization effects Open
Transcriptome analyses using high-throughput methodologies allow a deeper understanding of biological functions in different cell types/tissues. The present study provides an RNA-seq profiling of human sperm mRNAs and lncRNAs (messenger an…
View article: Chromosome heteromorphisms: do they entail a reproductive risk for male carriers?
Chromosome heteromorphisms: do they entail a reproductive risk for male carriers? Open
Dear Editor, Chromosome heteromorphisms are described as variations in size and morphology at specific regions that can be detected through classical banding methods. They are mitotically stable variants usually present in a heterozygous s…
View article: Sperm microRNA pairs: new perspectives in the search for male fertility biomarkers
Sperm microRNA pairs: new perspectives in the search for male fertility biomarkers Open
View article: The use of fluorescence in situ hybridization analysis on sperm: indications to perform and assisted reproduction technology outcomes
The use of fluorescence in situ hybridization analysis on sperm: indications to perform and assisted reproduction technology outcomes Open
View article: Effect of nut consumption on semen quality and functionality in healthy men consuming a Western-style diet: a randomized controlled trial
Effect of nut consumption on semen quality and functionality in healthy men consuming a Western-style diet: a randomized controlled trial Open
View article: Chromosome positioning and male infertility: it comes with the territory
Chromosome positioning and male infertility: it comes with the territory Open
View article: Unpaired sex chromosomes in metaphase I human spermatocytes locally modify autosomal bivalents positioning
Unpaired sex chromosomes in metaphase I human spermatocytes locally modify autosomal bivalents positioning Open
Altres ajuts: Universitat Autònoma de Barcelona (CF-180034)
View article: An exploratory study of predisposing genetic factors for DiGeorge/velocardiofacial syndrome
An exploratory study of predisposing genetic factors for DiGeorge/velocardiofacial syndrome Open
View article: Conservación de la fertilidad en tumor borderline de ovario
Conservación de la fertilidad en tumor borderline de ovario Open
Los tumores borderline de ovario implican bajo potencial de malignidad. Representan un grupo heterogéneo de proliferaciones epiteliales atípicas sin invasión estromal. FIGO 2014 es una clasificación de estadificación que involucra al Estad…
View article: A comprehensive analysis of chromosomal anomalies in metaphase II spermatocytes from infertile patients
A comprehensive analysis of chromosomal anomalies in metaphase II spermatocytes from infertile patients Open
Dear Editor, The scarce number of secondary spermatocytes in human seminiferous tubules and the complexity of analyzing chromosomes at metaphase II are the main causes of the limited knowledge we have about chromosome characteristics at th…
View article: Normalization matters: tracking the best strategy for sperm miRNA quantification
Normalization matters: tracking the best strategy for sperm miRNA quantification Open
This work was supported by the 2014/SGR00524 project (Agència de Gestió d'Ajuts Universitaris i de Recerca, Generalitat de Catalunya, Spain) and UAB CF-180034 grant (Universitat Autònoma de Barcelona). Celia Corral-Vazquez is a recipient o…
View article: Altered bivalent positioning in metaphase I human spermatocytes from Robertsonian translocation carriers
Altered bivalent positioning in metaphase I human spermatocytes from Robertsonian translocation carriers Open