Joan A. Loayza-Castro
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View article: Prevalence of Chronic Kidney Disease in Latin America: A Systematic Review and Meta-analysis
Prevalence of Chronic Kidney Disease in Latin America: A Systematic Review and Meta-analysis Open
Background: Chronic kidney disease (CKD) represents a global health concern, with particular significance in Latin America due to socioeconomic inequalities and heterogeneous health care systems. Objective: To determine the prevalence of C…
View article: Global prevalence of preeclampsia, eclampsia, and HELLP syndrome: a systematic review and meta-analysis
Global prevalence of preeclampsia, eclampsia, and HELLP syndrome: a systematic review and meta-analysis Open
Introduction Hypertensive disorders of pregnancy represent a leading cause of maternal and perinatal morbidity and mortality worldwide. However, prevalence estimates of preeclampsia, eclampsia, and HELLP syndrome vary considerably across s…
View article: Global prevalence of insulin resistance in the adult population: a systematic review and meta-analysis
Global prevalence of insulin resistance in the adult population: a systematic review and meta-analysis Open
Objective To determine the global prevalence of IR, evaluating differences according to study designs and population characteristics. Methodology A systematic review with meta-analysis was conducted. The search encompassed MEDLINE (PubMed)…
View article: Adverse Cardiovascular Events Are Infrequent but Significantly Associated With Systolic and Pre-Systolic Hypertension: An Occupational Cohort Study
Adverse Cardiovascular Events Are Infrequent but Significantly Associated With Systolic and Pre-Systolic Hypertension: An Occupational Cohort Study Open
While cardiovascular events were infrequent in this occupational cohort, those that occurred showed significant associations with both systolic hypertension and pre-systolic hypertension, suggesting the importance of systolic pressure moni…
View article: Prevalence of asthma in adults in Latin America
Prevalence of asthma in adults in Latin America Open
Asthma has a significant prevalence in the adult population of Latin America, although its magnitude varies according to diagnostic and sampling methods. This landscape reflects cultural and epidemiologic heterogeneity, demanding specific …
View article: Lifestyles according to disease duration in patients with diabetes and hypertension
Lifestyles according to disease duration in patients with diabetes and hypertension Open
Introduction: In patients with hypertension (HTN) and diabetes mellitus (DM), lifestyles should be optimal to avoid long-term complications. However, it is sometimes unclear whether the disease duration factor could contribute to their imp…
View article: Prevalence of diabetes and prediabetes in Peru: a systematic review and meta-analysis
Prevalence of diabetes and prediabetes in Peru: a systematic review and meta-analysis Open
Diabetes and prediabetes prevalence in Peru have increased significantly over the past decade, reaching concerning levels that require urgent public health attention. The substantial heterogeneity observed emphasizes the need for standardi…
View article: Trends and disparities in the coexistence of anemia and obesity among Peruvian women aged 20–49 years: doubling prevalence in two decades of National surveillance
Trends and disparities in the coexistence of anemia and obesity among Peruvian women aged 20–49 years: doubling prevalence in two decades of National surveillance Open
Not applicable.
View article: Abdominal obesity prevalence in Latin America: a systematic review and meta-analysis comparing ATP III and IDF criteria
Abdominal obesity prevalence in Latin America: a systematic review and meta-analysis comparing ATP III and IDF criteria Open
Background Abdominal obesity (AO) represents a significant cardiovascular risk factor with distinctive characteristics in Latin American populations. Its prevalence has increased substantially in recent decades, although estimates vary acc…
View article: A metabolic epidemic? Prevalence and sex-based disparities of metabolic alterations in the peruvian population using multiple diagnostic criteria
A metabolic epidemic? Prevalence and sex-based disparities of metabolic alterations in the peruvian population using multiple diagnostic criteria Open
Introduction Metabolic alterations constitute a growing challenge for global public health, with significant implications for cardiovascular morbidity and mortality. Early identification of these alterations, even from the presence of a si…
View article: Prevalence of Hypertension, Prehypertension, and High-normal Blood Pressure in Peru: A Systematic Review and Meta-analysis
Prevalence of Hypertension, Prehypertension, and High-normal Blood Pressure in Peru: A Systematic Review and Meta-analysis Open
Introduction Hypertension (HTN) is a major cardiovascular risk factor, with increasing concern over preceding conditions, such as prehypertension and high-normal blood pressure (HNBP). In Peru, the data on these conditions is heterogeneous…
View article: Geospatial analysis and determinant factors of comorbidity presence in patients with diabetes in Peru
Geospatial analysis and determinant factors of comorbidity presence in patients with diabetes in Peru Open
Objective: Given the significant increase in diabetes mellitus (DM) prevalence and its associated complications in recent decades, this study aimed to explore the determinant factors and geographical distribution of comorbidities and their…
View article: Prevalence and determinants of ideal cardiovascular health by sex and region—a population-based study in Peru
Prevalence and determinants of ideal cardiovascular health by sex and region—a population-based study in Peru Open
Introduction Attaining what the American Heart Association terms Ideal Cardiovascular Health (ICVH) is viewed as an essential objective for preventing cardiovascular diseases (CVD). Objective To determine the prevalence of ICVH, stratified…
View article: Prevalence and incidence of prediabetes in Latin America. A systematic review and meta-analysis
Prevalence and incidence of prediabetes in Latin America. A systematic review and meta-analysis Open
Introduction Prediabetes represents a significant public health challenge in Latin America. Its prevalence varies considerably depending on the diagnostic criteria used, which hinders a precise understanding of its magnitude in the region.…
View article: Sample Size and Statistical Power Calculation in Multivariable Analyses: Development and Implementation of "SampleSizeMulti" Packages in R
Sample Size and Statistical Power Calculation in Multivariable Analyses: Development and Implementation of "SampleSizeMulti" Packages in R Open
This paper presents advanced methodological approaches and practical tools for sample size calculation in epidemiological studies involving multivariable analyses. Traditional sample size calculation methods often fail to account for the c…
View article: Scientific Tasks in Biomedical and Oncological Research: Describing, Predicting, and Explaining
Scientific Tasks in Biomedical and Oncological Research: Describing, Predicting, and Explaining Open
The traditional classification of studies as descriptive and analytical has proven insufficient to capture the complexity of modern biomedical research, including oncology. This article proposes classification based on scientific tasks tha…
View article: Prevalence, trends, and associated factors of isolated systolic, diastolic, and systolic–diastolic hypertension in Peru: A nine-year analysis of the Demographic and Family Health Survey
Prevalence, trends, and associated factors of isolated systolic, diastolic, and systolic–diastolic hypertension in Peru: A nine-year analysis of the Demographic and Family Health Survey Open
Significant differences in the prevalence of HTN subtypes have been found, underscoring the heterogeneity of this chronic condition, both in related factors and in trends over the years.
View article: Interleukin-6 as a Risk and Prognostic Biomarker in Gastric Cancer: A Systematic Review and Meta-Analysis
Interleukin-6 as a Risk and Prognostic Biomarker in Gastric Cancer: A Systematic Review and Meta-Analysis Open
Introduction: Gastric cancer (GC) is one of the leading causes of cancer-related mortality worldwide. Interleukin-6 (IL-6) has been implicated in its pathogenesis and progression, but its role as a prognostic biomarker remains controversia…
View article: Lifestyles according to disease duration in patients with diabetes and hypertension
Lifestyles according to disease duration in patients with diabetes and hypertension Open
Introduction: In patients with hypertension (HTN) and diabetes mellitus (DM), lifestyles should be optimal to avoid long-term complications. However, it is sometimes unclear whether the disease duration factor could contribute to their imp…
View article: A Metabolic Epidemic? Prevalence and Sex-Based Disparities of Metabolic Alterations in the Peruvian Population Using Multiple Diagnostic Criteria
A Metabolic Epidemic? Prevalence and Sex-Based Disparities of Metabolic Alterations in the Peruvian Population Using Multiple Diagnostic Criteria Open
Introduction: Metabolic alterations constitute a growing challenge for global public health, with significant implications for cardiovascular morbidity and mortality. Early identification of these alterations, even from the presence of a s…
View article: Geospatial analysis of the presence of hypertension, diabetes, obesity, and lifestyles in the Peruvian population
Geospatial analysis of the presence of hypertension, diabetes, obesity, and lifestyles in the Peruvian population Open
Introduction: In Peru, the prevalence of diabetes mellitus (DM), hypertension (HTN), and obesity has increased significantly while healthy lifestyles have declined. However, the geographic distribution of these conditions at the provincial…
View article: Maternal obesogenic environment and its association with childhood obesity in Peru: A 9-year analysis of a national survey
Maternal obesogenic environment and its association with childhood obesity in Peru: A 9-year analysis of a national survey Open
Introduction: Childhood obesity is a global public health concern with increasing prevalence in Peru. The obesogenic environment, including maternal and family environmental factors, plays a crucial role in the development of childhood obe…
View article: Body Mass Index as a Risk Factor for Diffuse Large B-Cell Lymphoma: A Systematic Review and Meta-Analysis
Body Mass Index as a Risk Factor for Diffuse Large B-Cell Lymphoma: A Systematic Review and Meta-Analysis Open
Introduction: Given the increasing prevalence of obesity, as measured by the Body Mass Index (BMI), and the significant impact of Diffuse Large B-cell lymphoma (DLBCL) on global health, it is crucial to update our understanding of the rela…