Joan Comenge
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View article: A comprehensive review of competitive lateral flow assays over the past decade
A comprehensive review of competitive lateral flow assays over the past decade Open
Competitive LFAs are widely employed to detect targets ranging from small molecules to large proteins across diverse fields. This review explores their function using theoretical models and critically addresses factors affecting their perf…
Gold Nanoparticle Virus-like Particles Presenting SARS-CoV-2 Spike Protein: Synthesis, Biophysical Properties and Immunogenicity in BALB/c Mice Open
Gold nanoparticles (AuNPs) decorated with antigens have recently emerged as promising tools for vaccine development due to their innate ability to provide stability to antigens and modulate immune responses. In this study, we have engineer…
Stem cell delivery to kidney <i>via</i> minimally invasive ultrasound-guided renal artery injection in mice Open
Cell-based therapies are promising treatments for various kidney diseases. However, the major hurdle in initiating therapeutic responses is the inefficiency of injection routes to deliver cells to the kidney parenchyma. Systemic injection,…
Correction to Preventing Plasmon Coupling between Gold Nanorods Improves the Sensitivity of Photoacoustic Detection of Labeled Stem Cells <i>in Vivo</i> Open
ADVERTISEMENT RETURN TO ISSUEPREVAdditions and Correc...Additions and CorrectionsNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to Preventing Plasmon Coupling between Gold Nanorods Improves the Sensitivity of Photoacoustic Detec…
Multimodal cell tracking from systemic administration to tumour growth by combining gold nanorods and reporter genes Open
Understanding the fate of exogenous cells after implantation is important for clinical applications. Preclinical studies allow imaging of cell location and survival. Labelling with nanoparticles enables high sensitivity detection, but cell…
Author response: Multimodal cell tracking from systemic administration to tumour growth by combining gold nanorods and reporter genes Open
Article Figures and data Abstract eLife digest Introduction Results and discussion Materials and methods Data availability References Decision letter Author response Article and author information Metrics Abstract Understanding the fate of…
Non-invasive imaging reveals conditions that impact distribution and persistence of cells after <i>in vivo</i> administration Open
Background Cell-based regenerative medicine therapies are now frequently tested in clinical trials. In many conditions, cell therapies are administered systemically, but there is little understanding of their fate, and adverse events are o…
Multimodal cell tracking from systemic administration to tumour growth by combining gold nanorods and reporter genes Open
Understanding the fate of exogenous cells after implantation is important for clinical applications. Preclinical studies allow imaging of cell location and survival. Labelling with nanoparticles enables high sensitivity detection, but cell…
Data: Multimodal Cell Tracking From Systemic Administration To Tumour Growth By Combining Gold Nanorods And Reporter Genes Open
This data set includes multispectral optoacoustic tomography images supporting an article on cell tracking (preprint: bioRxiv 199836; https://doi.org/10.1101/199836). The corresponding bioluminescence results are included too, as well as t…
Data: Multimodal Cell Tracking From Systemic Administration To Tumour Growth By Combining Gold Nanorods And Reporter Genes Open
This data set includes multispectral optoacoustic tomography images supporting an article on cell tracking (preprint: bioRxiv 199836; https://doi.org/10.1101/199836). The corresponding bioluminescence results are included too, as well as t…
Characterizing Self-Assembled Monolayers on Gold Nanoparticles Open
A key aspect of nanoscience is to control the assembly of complex materials from a "bottom-up" approach. The self-assembly and self-organization of small ligands at the surface of nanoparticles represent a possible starting route for the p…
Preventing Plasmon Coupling between Gold Nanorods Improves the Sensitivity of Photoacoustic Detection of Labeled Stem Cells <i>in Vivo</i> Open
Gold nanorods are excellent contrast agents for imaging technologies which rely on near-infrared absorption such as photoacoustic imaging. For cell tracking applications, the cells of interest are labeled with the contrast agent prior to i…
TEM images of cells labelled with GNR-PEG Open
TEM images of cells labelled with GNRs capped with PEG-COOH. GNRs are tightly packed in subcellular vesicles, which is ultimately translated in plasmon coupling. Therefore, cells labelled with these GNRs did not have the typical GNRs optic…
TEM images of GNR-Si23 Open
TEM images of GNR-Si23. Gold nanorods coated with a 23 nm silica shell
Photothermal evaluation of GNR uptake (30 pM) Open
Images of cells treated with 30 pM GNRs-Si35 for 24 h and corresponding transmitted light images.
TEM images of GNR-Si15 Open
TEM images of GNR-Si15. Gold nanorods coated with a 15 nm silica shell.
MSOT images corresponding to a scan of a mouse after subcutaneous injection of cells (day 1). Multispectral reconstruction and background. Open
2x104, 1x105, and 2x105 GNR-Si35-labelled (30 pM) MSCs, as well as 2x105 control cells were subcutaneously injected at 4 different positions into the flank of a mouse, and monitored for up to 15 days. Scans of the mouse flank from shoulder…
Videos corresponding to migration assay Open
Videos corresponding to the migration assay
MSOT images corresponding to a scan of a mouse after subcutaneous injection of cells (day 10) Open
2x104, 1x105, and 2x105 GNR-Si35-labelled (30 pM) MSCs, as well as 2x105 control cells were subcutaneously injected at 4 different positions into the flank of a mouse, and monitored for up to 15 days. Scans of the regions where cells where…
Photothermal evaluation of GNR uptake (10 pM) Open
Images of cells treated with 10 pM GNRs-Si35 for 24 h and corresponding transmitted light images.
MSOT images corresponding to a scan of a mouse after subcutaneous injection of cells (day 3). All positions, all wavelengths. Open
2x104, 1x105, and 2x105 GNR-Si35-labelled (30 pM) MSCs, as well as 2x105 control cells were subcutaneously injected at 4 different positions into the flank of a mouse, and monitored for up to 15 days. Scans of the regions where cells were …
TEM images of GNR-Si35 Open
TEM images of GNR-Si35. Gold nanorods coated with a 35 nm silica shell.
Videos corresponding to migration assay Open
Videos corresponding to the migration assay