Joana Rodrigues Dantas
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View article: The importance of using the oral glucose tolerance test when assessing the glycemic profile in patients with adrenal incidentaloma
The importance of using the oral glucose tolerance test when assessing the glycemic profile in patients with adrenal incidentaloma Open
Introduction There are limited data regarding the role of oral glucose tolerance test (OGTT) in classifying glycemic alterations in patients with adrenal incidentaloma (AI). This study aims to compare the frequency of dysglycemia [pre-diab…
View article: Correction: Type 1 diabetes in Brazil: a narrative overview of the Brazilian Type 1 Diabetes Study Group
Correction: Type 1 diabetes in Brazil: a narrative overview of the Brazilian Type 1 Diabetes Study Group Open
View article: Long-Term Clinical Experience With Metreleptin in a Brazilian Patient With Congenital Generalized Lipodystrophy Type 2
Long-Term Clinical Experience With Metreleptin in a Brazilian Patient With Congenital Generalized Lipodystrophy Type 2 Open
We describe our 8-year clinical experience with metreleptin in a Brazilian adult female patient with congenital generalized lipodystrophy type 2 (due to a mutation in the BSCL2 gene) and severe insulin resistance. The patient was initially…
View article: Type 1 diabetes technology gap between high‐income and developing countries: Continuous glucose monitoring access remains a challenge in Brazil
Type 1 diabetes technology gap between high‐income and developing countries: Continuous glucose monitoring access remains a challenge in Brazil Open
View article: Effects of lifestyle changes in patients with metabolic syndrome and heart disease
Effects of lifestyle changes in patients with metabolic syndrome and heart disease Open
This study aimed to analyze how lifestyle changes have impacted the treatment of Metabolic Syndrome (MS) and Systemic Arterial Hypertension (SAH). A systematic review of the literature was conducted using the electronic databases: PubMed a…
View article: Brazilian expert consensus on the diagnosis, classification, screening for complications and treatment of familial partial lipodystrophy
Brazilian expert consensus on the diagnosis, classification, screening for complications and treatment of familial partial lipodystrophy Open
View article: An analysis of the remission phase in type 1 diabetes within a multiethnic Brazilian sample
An analysis of the remission phase in type 1 diabetes within a multiethnic Brazilian sample Open
View article: Comprehensive analysis of morbidity and mortality patterns in familial partial lipodystrophy patients: insights from a population study
Comprehensive analysis of morbidity and mortality patterns in familial partial lipodystrophy patients: insights from a population study Open
Background There is a lack of information on the clinical and molecular presentation of familial partial lipodystrophy (FPLD), a rare genetic disorder characterized by partial subcutaneous fat loss. Objective This study aimed to provide a …
View article: Evaluation of type 1 diabetes’ partial clinical remission after three years of heterologous adipose tissue derived stromal/stem cells transplantation associated with vitamin D supplementation
Evaluation of type 1 diabetes’ partial clinical remission after three years of heterologous adipose tissue derived stromal/stem cells transplantation associated with vitamin D supplementation Open
Background Mesenchymal stem cell infusion and vitamin D supplementation may have immunomodulatory actions that could prolong the preservation of residual insulin secretion in patients with type 1 diabetes (T1D). Intervention with these age…
View article: Immunomodulatory agents and cell therapy for patients with type 1 diabetes
Immunomodulatory agents and cell therapy for patients with type 1 diabetes Open
Type 1 diabetes (TID) is a chronic disease caused by autoimmune destruction of pancreatic β-cells, that progresses in three stages: 1) stage 1: β-cell autoimmunity + normoglycemia; 2) stage 2: β-cell autoimmunity + mild dysglycemia; 3) sta…
View article: Prevalence of overweight/obesity and its relationship with metabolic syndrome and fatty liver index in adult patients with type 1 diabetes. A Brazilian multicenter study
Prevalence of overweight/obesity and its relationship with metabolic syndrome and fatty liver index in adult patients with type 1 diabetes. A Brazilian multicenter study Open
Aims To determine the prevalence of overweight/obesity and its relationship with metabolic syndrome (MS), fatty liver index (FLI), cardiovascular risk factors (CVRF), and diabetes-related chronic complications (DRCC) in adult patients with…
View article: Adipose tissue-derived stromal/stem cells transplantation + cholecalciferol in recent-onset type 1 diabetes patients: twelve months follow up.
Adipose tissue-derived stromal/stem cells transplantation + cholecalciferol in recent-onset type 1 diabetes patients: twelve months follow up. Open
OBJECTIVE: To evaluate safety and therapeutic effect along 12 months of allogenic adipose tissue-derived stromal/stem cells (ASCs) transplantation+cholecalciferol(VITD) in patients with recent-onset type 1 diabetes (T1D). METHODS: Prospect…
View article: Binge eating disorder, frequency of depression, and systemic inflammatory state in individuals with obesity – A cross sectional study
Binge eating disorder, frequency of depression, and systemic inflammatory state in individuals with obesity – A cross sectional study Open
Individuals with obesity and BED showed greater psychiatric comorbidity, worse eating patterns and worse inflammatory profile than those without BED. BED should be assessed as an indicator of clinical severity in patients with obesity.
View article: Ten years follow up of first degree relatives of type 1 diabetes patients: presence of autoimmune biomarkers and the progression to diabetes in a retrospective cohort
Ten years follow up of first degree relatives of type 1 diabetes patients: presence of autoimmune biomarkers and the progression to diabetes in a retrospective cohort Open
In Brazilian FDR of T1DM patients, the positivity for multiple autoantibodies indicate a greater chance of progression to T1DM, similar to observed in Caucasians. ZnT8A was helpful in the risk assessment for T1DM development.
View article: Adipose tissue-derived stromal/stem cells + cholecalciferol: a pilot study in recent-onset type 1 diabetes patients
Adipose tissue-derived stromal/stem cells + cholecalciferol: a pilot study in recent-onset type 1 diabetes patients Open
Allogenic ASC + VIT D without immunosuppression was safe and might have a role in the preservation of β-cells in patients with recent-onset T1D. ClinicalTrials.gov: NCT03920397.
View article: HbA1c variability and long-term glycemic control are linked to peripheral neuropathy in patients with type 1 diabetes
HbA1c variability and long-term glycemic control are linked to peripheral neuropathy in patients with type 1 diabetes Open
Background HbA1c variability has been linked to retinopathy, renal disease and autonomic neuropathy in patients with type 1 diabetes mellitus (T1D) and type 2 diabetes mellitus (T2D). Although the same relationship has been demonstrated fo…
View article: Severity and mortality of COVID 19 in patients with diabetes, hypertension and cardiovascular disease: a meta-analysis
Severity and mortality of COVID 19 in patients with diabetes, hypertension and cardiovascular disease: a meta-analysis Open
View article: Allogenic Adipose Tissue-Derived Stromal/Stem Cells and Vitamin D Supplementation in Patients With Recent-Onset Type 1 Diabetes Mellitus: A 3-Month Follow-Up Pilot Study
Allogenic Adipose Tissue-Derived Stromal/Stem Cells and Vitamin D Supplementation in Patients With Recent-Onset Type 1 Diabetes Mellitus: A 3-Month Follow-Up Pilot Study Open
Objective: To evaluate the short term safety and potential therapeutic effect of allogenic adipose tissue-derived stromal/stem cells (ASCs) + cholecalciferol in patients with recent-onset T1D. Methods: Prospective, phase II, …
View article: Association between high titers of glutamic acid decarboxylase antibody and epilepsy in patients with type 1 diabetes mellitus: A cross-sectional study
Association between high titers of glutamic acid decarboxylase antibody and epilepsy in patients with type 1 diabetes mellitus: A cross-sectional study Open
View article: Postprandial metabolic effects of fructose and glucose in type 1 diabetes patients: a pilot randomized crossover clinical trial
Postprandial metabolic effects of fructose and glucose in type 1 diabetes patients: a pilot randomized crossover clinical trial Open
Fructose and glucose had similar sweetness, flavor and aftertaste characteristics and did not change triglycerides, lactate or glucagon levels. Although fructose resulted in lower postprandial BG than glucose, it increased uric acid and ma…
View article: Postprandial metabolic effects of fructose and glucose in type 1 diabetes patients: a pilot randomized crossover clinical trial
Postprandial metabolic effects of fructose and glucose in type 1 diabetes patients: a pilot randomized crossover clinical trial Open
Objective To test the influence of oral fructose and glucose dose-response solutions in blood glucose (BG), glucagon, triglycerides, uricaemia, and malondialdehyde in postprandial states in type 1 diabetes mellitus (T1DM) patients. Subject…
View article: Postprandial metabolic effects of fructose and glucose in type 1 diabetes patients: a pilot randomized crossover clinical trial
Postprandial metabolic effects of fructose and glucose in type 1 diabetes patients: a pilot randomized crossover clinical trial Open
Objective To test the influence of oral fructose and glucose dose-response solutions in blood glucose (BG), glucagon, triglycerides, uricaemia, and malondialdehyde in postprandial states in type 1 diabetes mellitus (T1DM) patients. Subject…
View article: Thyroid disorders are common in first-degree relatives of individuals with type 1 diabetes mellitus
Thyroid disorders are common in first-degree relatives of individuals with type 1 diabetes mellitus Open
Objective Thyroid diseases are common in individuals with type 1 diabetes mellitus (T1DM) and should be investigated annually in these individuals. The aim of this study was to evaluate the frequency of thyroid diseases in first degree rel…
View article: Treino e reforço de competências em doentes renais crónicos em hemodiálise – O Programa “Acredita+ e Segue”: Resultados preliminares
Treino e reforço de competências em doentes renais crónicos em hemodiálise – O Programa “Acredita+ e Segue”: Resultados preliminares Open
Objetivo: O presente estudo apresenta os resultados preliminares e descreve a estrutura de um programa de treino e reforço de competências assente numa metodologia de Serviço Social de grupo, realizado a partir das necessidades de doentes …
View article: Comparative study of perinatal outcomes between pregnant women with gestational diabetes mellitus diagnosed by the new IADPSG and the old ADA criteria
Comparative study of perinatal outcomes between pregnant women with gestational diabetes mellitus diagnosed by the new IADPSG and the old ADA criteria Open
View article: The impact of sustained hyperglycemia, metabolic memory and hba1c variability in the development of chronic complications in patients with type 1 diabetes
The impact of sustained hyperglycemia, metabolic memory and hba1c variability in the development of chronic complications in patients with type 1 diabetes Open
View article: High normal TSH is associated with retinopathy and increased albumin excretion in euthyroid type 1 diabetic patients
High normal TSH is associated with retinopathy and increased albumin excretion in euthyroid type 1 diabetic patients Open
View article: Prospective evaluation of glutamine and phospholipids levels in first degree relatives of patients with Type 1 Diabetes from a multiethnic population
Prospective evaluation of glutamine and phospholipids levels in first degree relatives of patients with Type 1 Diabetes from a multiethnic population Open
View article: Thyroid disorders are common in first-degree relatives of individuals with type 1 diabetes mellitus
Thyroid disorders are common in first-degree relatives of individuals with type 1 diabetes mellitus Open
Thyroid abnormalities seem to be common not only in patients with T1DM but also in their FDR, which suggests that screening strategies for thyroid diseases might also be useful to these individuals.
View article: New onset diabetes mellitus after kidney transplant: prevalence and risk factors
New onset diabetes mellitus after kidney transplant: prevalence and risk factors Open
Background New onset diabetes mellitus after transplant (NODAT) has been described in 4-25% of kidney transplant recipients. It is not only a major factor leading to dysfunction and deterioration of the allograft, but also has a significan…