Joanna Bartosińska
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View article: The Effectiveness of Micro-Needle Mesotherapy with Seboregulatory Ampoule in the Treatment of Oily Skin
The Effectiveness of Micro-Needle Mesotherapy with Seboregulatory Ampoule in the Treatment of Oily Skin Open
Background: Contemporary dermatology and cosmetology continue to explore effective strategies for normalizing the function of oily skin, where excessive sebum production and impairment of the hydrolipid barrier pose considerable therapeuti…
View article: The Prevalence of Symptomatic Dermographism: Results of the International <scp>UCARE PREVALENCE</scp>‐D Study
The Prevalence of Symptomatic Dermographism: Results of the International <span>UCARE PREVALENCE</span>‐D Study Open
Background The prevalence of symptomatic dermographism ( SD ) in the general population remains unclear. This study aimed to internationally estimate the prevalence of SD and two other dermographic subtypes—physiological red dermographism …
View article: Evaluation of the Percentage of Monocyte Subpopulations with TLR2 and TLR4 Expression About Selected Skin Functional Parameters in Patients with Acne Vulgaris—Cross-Sectional Study
Evaluation of the Percentage of Monocyte Subpopulations with TLR2 and TLR4 Expression About Selected Skin Functional Parameters in Patients with Acne Vulgaris—Cross-Sectional Study Open
Background/Objectives: Acne vulgaris can be non-inflammatory lesions, i.e., closed comedones, open comedones, inflammatory lesions, i.e., papules, pustules, cysts, and post-acne lesions. This study aimed to evaluate the expression of TLR2 …
View article: Signs and symptoms of vulval lichen sclerosus in children and adolescents: a scoping review protocol
Signs and symptoms of vulval lichen sclerosus in children and adolescents: a scoping review protocol Open
Introduction Paediatric vulval lichen sclerosus (VLS) is a chronic disease with distressing symptoms and severe consequences when left untreated. Majority of existing data on pathophysiology and treatment is based on studies conducted amon…
View article: Aberrant Expression of BTLA, CD160, SPN, TIM-3, VISTA and TIGIT in Chronic Lymphocytic Leukemia and Psoriasis Patients Compared to Healthy Volunteers
Aberrant Expression of BTLA, CD160, SPN, TIM-3, VISTA and TIGIT in Chronic Lymphocytic Leukemia and Psoriasis Patients Compared to Healthy Volunteers Open
Background: Currently, much attention is focused on the interactions between the leukemic and psoriatic cells showing immunosuppressive activity within the microenvironment. Methods: Our study assessed a collective mRNA expression pattern …
View article: Aberrant Expression of <i>BTLA</i>, <i>CD160</i>, <i>SPN</i>, <i>TIM-3</i>, <i>VISTA</i> and <i>TIGIT</i> in Chronic Lymphocytic Leukemia and Psoriasis Patients Compared to Healthy Volunteers
Aberrant Expression of <i>BTLA</i>, <i>CD160</i>, <i>SPN</i>, <i>TIM-3</i>, <i>VISTA</i> and <i>TIGIT</i> in Chronic Lymphocytic Leukemia and Psoriasis Patients Compared to Healthy Volunteers Open
Currently, many attention is focus on the interactions between the leukemic and psoriatic cells showing immunosuppressive activity within the microenvironment. Our study assessed a collective mRNA expression pattern of crucial immuno-regul…
View article: Epidemiology of Psoriasis in Poland: Prevalence, Incidence, and Mortality Rates
Epidemiology of Psoriasis in Poland: Prevalence, Incidence, and Mortality Rates Open
Background Although the data on psoriasis epidemiology included in the Global Psoriasis Atlas (GPA) provide valuable information on psoriasis prevalence worldwide, the GPA database is still incomplete. Therefore, the aim of the study was t…
View article: A review of photodynamic therapy for the treatment of viral skin diseases
A review of photodynamic therapy for the treatment of viral skin diseases Open
Introduction: Photodynamic therapy (PDT) is a two-stage treatment method making use of light energy and a photosensitizer in the presence of oxygen. PDT has already proved to bring good anti-inflammatory and anti-proliferative effects in t…
View article: Critical Ischemia Following Hyaluronic Acid Filler Injection: A Case Report
Critical Ischemia Following Hyaluronic Acid Filler Injection: A Case Report Open
Background: Vascular complications, following the application of non-permanent, hyaluronic acid-based tissue fillers are a rare but very serious and rapidly progressive disorder that can, in extreme cases, lead to skin necrosis, blindness,…
View article: Hormonal Status and Quality of Life of Women Treated for Infertility Before and During COVID-19 Pandemic in Poland
Hormonal Status and Quality of Life of Women Treated for Infertility Before and During COVID-19 Pandemic in Poland Open
Background/Objectives: Infertile people experience a lot of psychological stress due to the inability to conceive and achieve pregnancy. Studies on the quality of life (QoL) of people undergoing infertility treatment typically show a lower…
View article: Micro-needling: current state of knowledge and clinicalapplications: a review
Micro-needling: current state of knowledge and clinicalapplications: a review Open
Micro-needling mesotherapy is one of the increasingly popular treatments in dermatology clinics due to its wide range of effects on the skin. During the procedure, "micro-channels" are created in the epidermis, which remain open for a shor…
View article: Patient-Reported Outcome Measures in Atopic Dermatitis and Chronic Urticaria Are Underused in Clinical Practice
Patient-Reported Outcome Measures in Atopic Dermatitis and Chronic Urticaria Are Underused in Clinical Practice Open
Although PROMs offer several benefits, their use in routine practice is suboptimal, and physicians perceive barriers to their use. It is essential to attain higher levels of PROM implementation in accordance with national and international…
View article: Efficacy of photodynamic therapy using ALAHCl in gel with a lipid nanoemulsion and MALHCl in cream in superficial basal cell carcinoma
Efficacy of photodynamic therapy using ALAHCl in gel with a lipid nanoemulsion and MALHCl in cream in superficial basal cell carcinoma Open
Both formulations - ALA-HCl in gel and MAL-HCl in cream - were highly effective photosensitisers for PDT. The advantage of ALA-HCl in a gel formulation with a lipid nanoemulsion was faster skin healing, resulting in better cosmetic results.
View article: Red LED light therapy for telogen effluvium in the course of long COVID in patients with and without androgenetic alopecia
Red LED light therapy for telogen effluvium in the course of long COVID in patients with and without androgenetic alopecia Open
The study revealed that LED therapy is safe, well tolerated and seems to be a promising therapeutic option for TE in patients with long COVID. It can be used as adjuvant therapy leading to faster reduction of hair loss, enhancing hair regr…
View article: The Expression of Activation Markers CD25 and CD69 Increases during Biologic Treatment of Psoriasis
The Expression of Activation Markers CD25 and CD69 Increases during Biologic Treatment of Psoriasis Open
CD (cluster of differentiation) 69 and CD25 are considered early and late markers of the activation of lymphocytes, respectively. CD25 is a part of the IL-2 receptor and is present on the surface of immune and non-immune cells, with high a…
View article: Urticaria exacerbations and adverse reactions in patients with chronic urticaria receiving COVID-19 vaccination: Results of the UCARE COVAC-CU study
Urticaria exacerbations and adverse reactions in patients with chronic urticaria receiving COVID-19 vaccination: Results of the UCARE COVAC-CU study Open
View article: Comparison of Nailfold Videocapillaroscopy with Retinal and Choroidal Vascular Parameters in Patients with Central Serous Chorioretinopathy
Comparison of Nailfold Videocapillaroscopy with Retinal and Choroidal Vascular Parameters in Patients with Central Serous Chorioretinopathy Open
Aim: This study seeks to evaluate the results of nailfold videocapillaroscopies (NVCs) among patients with central serous chorioretinopathy (CSC) and their correlation with the choroid and retinal parameters. Material and Methods: The exam…
View article: The Impact of Biologic Treatment on PD-1/PD-L1 Pathway Disturbances in Psoriasis
The Impact of Biologic Treatment on PD-1/PD-L1 Pathway Disturbances in Psoriasis Open
The programmed death-1 (PD-1) receptor plays a major physiological role in the maintenance of immune tolerance and, by interaction with its ligands (PD-L1 and PD-L2), prevents the development of multiple immune-mediated diseases. There is …
View article: An Impact of Biologic Treatment on PD-1/PD-L1 Pathway Disturbances in Psoriasis
An Impact of Biologic Treatment on PD-1/PD-L1 Pathway Disturbances in Psoriasis Open
Programmed-death-1 (PD-1) receptor plays a major physiological role in maintainance of im-mune tolerance, and, by interaction with its ligands (PD-L1 and PD-L2), prevents the develop-ment of multiple immune-mediated diseases. There is grow…
View article: Results of Nailfold Videocapillaroscopy in Patients with Pseudoexfoliative Glaucoma
Results of Nailfold Videocapillaroscopy in Patients with Pseudoexfoliative Glaucoma Open
The aim of this study was to evaluate the nailfold videocapillaroscopic examination results from patients with pseudoexfoliative glaucoma (XFG) and to assess the relationship between the results of this examination and the patient’s clinic…
View article: Risankizumab Therapy for Moderate-to-Severe Psoriasis—A Multi-Center, Long-Term, Real-Life Study from Poland
Risankizumab Therapy for Moderate-to-Severe Psoriasis—A Multi-Center, Long-Term, Real-Life Study from Poland Open
The present multi-center, long-term, real-life study made an attempt to assess the efficacy of risankizumab in the treatment of moderate-to-severe plaque psoriasis. The study comprised 185 patients from 10 Polish dermatologic departments u…
View article: Multiple Cytokine Analysis of Th1/Th2/Th9/Th17/Th22/Treg Cytokine Pathway for Individual Immune Profile Assessment in Patients with Psoriasis
Multiple Cytokine Analysis of Th1/Th2/Th9/Th17/Th22/Treg Cytokine Pathway for Individual Immune Profile Assessment in Patients with Psoriasis Open
BACKGROUND Psoriasis is an autoimmune and autoinflammatory disorder that has a significant impact on patient quality of life. The aim of the study was to assess the immune profiles of patients with psoriasis with multiple cytokine analysis…
View article: The Analysis of a Genome-Wide Association Study (GWAS) of Overweight and Obesity in Psoriasis
The Analysis of a Genome-Wide Association Study (GWAS) of Overweight and Obesity in Psoriasis Open
There is evidence that the concomitance of psoriasis and obesity may originate from the interplay between multiple genetic pathways and involve gene–gene interactions. The aim of this study was to compare the genetic background related to …
View article: The Role of Skin Immune System in Acne
The Role of Skin Immune System in Acne Open
Acne vulgaris is a skin disease that often occurs in adolescence and in young adulthood. The main pathogenic factors are hyperkeratinization, obstruction of sebaceous glands, stimulation of sebaceous gland secretion by androgens, and bacte…
View article: Chronic Plaque Psoriasis in Poland: Disease Severity, Prevalence of Comorbidities, and Quality of Life
Chronic Plaque Psoriasis in Poland: Disease Severity, Prevalence of Comorbidities, and Quality of Life Open
The epidemiology of psoriasis has not been widely assessed in Polish population so far. This study aimed to investigate psoriasis epidemiological situation by evaluating disease course and severity, management, comorbidities, environmental…
View article: Topical Photodynamic Therapy with Different Forms of 5-Aminolevulinic Acid in the Treatment of Actinic Keratosis
Topical Photodynamic Therapy with Different Forms of 5-Aminolevulinic Acid in the Treatment of Actinic Keratosis Open
Photodynamic therapy (PDT) is safe and effective in the treatment of patients with actinic keratosis (AK). The aim of the study was to assess the efficacy, tolerability and cosmetic outcome of topical PDT in the treatment of AKs with three…
View article: The Impact of Hypertension, Diabetes, Lipid Disorders, Overweight/Obesity and Nicotine Dependence on Health-Related Quality of Life and Psoriasis Severity in Psoriatic Patients Receiving Systemic Conventional and Biological Treatment
The Impact of Hypertension, Diabetes, Lipid Disorders, Overweight/Obesity and Nicotine Dependence on Health-Related Quality of Life and Psoriasis Severity in Psoriatic Patients Receiving Systemic Conventional and Biological Treatment Open
Psoriasis, a chronic disease, is associated with a higher prevalence of comorbidities and has negative impact on health-related quality of life (HRQOL). The objective was to investigate the effect of comorbidities on HRQOL, and psoriasis s…
View article: Novel Application of Light-Emitting Diode Therapy in the Treatment of Eyebrow Loss in Frontal Fibrosing Alopecia
Novel Application of Light-Emitting Diode Therapy in the Treatment of Eyebrow Loss in Frontal Fibrosing Alopecia Open
Background: Eyebrow loss in the course of frontal fibrosing alopecia (FFA) is becoming a growing issue among older females. It has a considerable negative impact on patients’ quality of life. Since there is no standardized treatment, photo…
View article: The Genetic Variants of NOTCH3 (6746T>C) and PSMA6 (-8C>G) as Possible Risk Factors of Psoriasis Development
The Genetic Variants of NOTCH3 (6746T>C) and PSMA6 (-8C>G) as Possible Risk Factors of Psoriasis Development Open
Advances in genotypic technologies enable identification of possible associations between genetic variants of certain genes and increased risk of developing plaque psoriasis or psoriatic arthritis. The aim of the study was to analyze the N…
View article: The Genetic Variants of NOTCH3 (6746T&gt;C) and PSMA6 (-8C&gt;G) As Possible Risk Factors of Psoriasis Development
The Genetic Variants of NOTCH3 (6746T>C) and PSMA6 (-8C>G) As Possible Risk Factors of Psoriasis Development Open
Advances in genotypic technologies enable identification of possible associations between genetic variants of certain genes and increased risk of developing plaque psoriasis or psoriatic arthritis. The aim of the study was to analyze the N…