Joanna Bronikowska
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View article: Exploring the Interplay of TGF-β and Body Weight in Thyroid Cancer: A Comparative Analysis of Cytokine Levels Before and After Surgery in Differentiated Thyroid Cancer and Obese Patients with Nodular Goiter
Exploring the Interplay of TGF-β and Body Weight in Thyroid Cancer: A Comparative Analysis of Cytokine Levels Before and After Surgery in Differentiated Thyroid Cancer and Obese Patients with Nodular Goiter Open
Introduction: Thyroid cancer and obesity are prevalent conditions with significant global health implications. Differentiated thyroid cancer (DTC) is influenced by various molecular pathways, including those involving Transforming Growth F…
View article: Methyl Derivatives of Flavone as Potential Anti-Inflammatory Compounds
Methyl Derivatives of Flavone as Potential Anti-Inflammatory Compounds Open
Flavones are natural compounds that are broadly distributed in our diet. Their unique properties provide the possibility to control the immune system and the process of inflammation. A high intake of flavonoids, including flavones, may off…
View article: The Effect of Methyl-Derivatives of Flavanone on MCP-1, MIP-1β, RANTES, and Eotaxin Release by Activated RAW264.7 Macrophages
The Effect of Methyl-Derivatives of Flavanone on MCP-1, MIP-1β, RANTES, and Eotaxin Release by Activated RAW264.7 Macrophages Open
Chemokines, also known as chemotactic cytokines, stimulate the migration of immune cells. These molecules play a key role in the pathogenesis of inflammation leading to atherosclerosis, neurodegenerative disorders, rheumatoid arthritis, in…
View article: Analysis of Cytokine and Chemokine Level in Tear Film in Keratoconus Patients before and after Corneal Cross-Linking (CXL) Treatment
Analysis of Cytokine and Chemokine Level in Tear Film in Keratoconus Patients before and after Corneal Cross-Linking (CXL) Treatment Open
Keratoconus (KC) is a degenerative corneal disorder whose aetiology remains unknown. The aim of our study was to analyse the expressions of cytokines and chemokines in KC patients before and after specified time intervals after corneal cro…
View article: Level of Secretion and the Role of the Nerve Growth Factor in Patients with Keratoconus before and after Collagen Fibre Cross-Linking Surgery
Level of Secretion and the Role of the Nerve Growth Factor in Patients with Keratoconus before and after Collagen Fibre Cross-Linking Surgery Open
Background: The aim of this study was to analyse the concentration of the nerve growth factor (NGF-β) in patients with keratoconus (KC) who are undergoing collagen fibre cross-linking (CXL) surgery in order to better understand the pathoge…
View article: In Vitro Anti-Inflammatory Activity of Methyl Derivatives of Flavanone
In Vitro Anti-Inflammatory Activity of Methyl Derivatives of Flavanone Open
Inflammation plays an important role in the immune defense against injury and infection agents. However, the inflammatory chronic process may lead to neurodegenerative diseases, atherosclerosis, inflammatory bowel diseases, or cancer. Flav…
View article: The modulating effect of methoxy-derivatives of 2’-hydroxychalcones on the release of IL-8, MIF, VCAM-1 and ICAM-1 by colon cancer cells
The modulating effect of methoxy-derivatives of 2’-hydroxychalcones on the release of IL-8, MIF, VCAM-1 and ICAM-1 by colon cancer cells Open
Colon cancer is one of the leading causes of death in the world. The search for effective and minimally invasive methods of treating colon cancer is the aim of modern medicine. Chalcones and their derivatives have shown an anticancer activ…
View article: The influence of cytomegalovirus on pathogenesis of ischemic heart disease
The influence of cytomegalovirus on pathogenesis of ischemic heart disease Open
View article: Novel Structurally Related Flavones Augment Cell Death Induced by rhsTRAIL
Novel Structurally Related Flavones Augment Cell Death Induced by rhsTRAIL Open
TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) was identified as a powerful activator of apoptosis in tumor cells and one of the most promising candidates for cancer therapy with no toxicity against normal tissues. However…