Joanna Yuet‐ling Tung
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View article: Correction: Vitamin D status and its determinants among Chinese infants and toddlers in Hong Kong
Correction: Vitamin D status and its determinants among Chinese infants and toddlers in Hong Kong Open
View article: Role of Active Video Games in Blood Pressure Management Among Children and Young Adults: Systematic Review and Meta-Analysis
Role of Active Video Games in Blood Pressure Management Among Children and Young Adults: Systematic Review and Meta-Analysis Open
Background The significant association between blood pressure (BP) in children and young adulthood and risks of cardiovascular diseases in adulthood highlights the critical need for early BP control. While lifestyle modifications such as i…
View article: Vitamin D status and its determinants among Chinese infants and toddlers in Hong Kong
Vitamin D status and its determinants among Chinese infants and toddlers in Hong Kong Open
Purpose Vitamin D is a micronutrient that is necessary for bone health as well as the regulation of mineral homeostasis. This study aims to assess the vitamin D status and its determinants among infants and toddlers in Hong Kong, two of th…
View article: Societal views on using risk-based innovations to inform cancer screening and referral policies: findings from three community juries
Societal views on using risk-based innovations to inform cancer screening and referral policies: findings from three community juries Open
Background Recent advances mean that innovations are emerging that enable better stratification of individuals based on their risk of cancer so that screening or diagnostic investigations can be targeted to those at greatest need. We explo…
View article: The protective role of vitamin D in BNT162b2 vaccine-related acute myocarditis
The protective role of vitamin D in BNT162b2 vaccine-related acute myocarditis Open
Introduction Vaccine-related myocarditis is recognized as a rare but important complication, especially after mass-scale mRNA COVID-19 vaccination. Knowledge regarding how to minimize the risk is limited. As NK cells can mediate acute myoc…
View article: Molecular genetic diagnosis and surgical management in a cohort of children with 46,XY disorders/differences of sex development
Molecular genetic diagnosis and surgical management in a cohort of children with 46,XY disorders/differences of sex development Open
Objective A firm diagnosis revealing the etiology of disorders/differences of sex development (DSD) is most helpful in guiding clinical management. The aim of this study is to investigate molecular genetic diagnoses and surgical treatment …
View article: Effects of a Ketogenic Diet on Anthropometric and Biochemical Parameters of Adolescents With Obesity and Nonalcoholic Fatty Liver Disease: A Randomized Controlled Trial
Effects of a Ketogenic Diet on Anthropometric and Biochemical Parameters of Adolescents With Obesity and Nonalcoholic Fatty Liver Disease: A Randomized Controlled Trial Open
View article: Association of vitamin D‐binding protein polymorphisms and serum 25(OH)D concentration varies among Chinese healthy infants of different <scp>VDR‐FokI</scp> genotypes: A multi‐centre cross‐sectional study
Association of vitamin D‐binding protein polymorphisms and serum 25(OH)D concentration varies among Chinese healthy infants of different <span>VDR‐FokI</span> genotypes: A multi‐centre cross‐sectional study Open
Hypovitaminosis D during infancy is associated with the development of chronic diseases and poor health later in life. While the effect of environmental factors on vitamin D concentration has been extensively explored, this study aimed to …
View article: Natural history of infants with vitamin D deficiency in Hong Kong.
Natural history of infants with vitamin D deficiency in Hong Kong. Open
Persistent VDD is common among infants exclusively breastfeeding and those who did not receive vitamin D supplementation.
View article: Bone Health Status of Children with Spinal Muscular Atrophy
Bone Health Status of Children with Spinal Muscular Atrophy Open
Background: Spinal muscular atrophy (SMA) is a group of rare, inherited neuromuscular disorders. Bone health is often a neglected issue in children with SMA. This study aimed to evaluate the bone health status of children with SMA in Hong …
View article: Incidence and Predictors for Oncologic Etiologies in Chinese Children with Pituitary Stalk Thickening
Incidence and Predictors for Oncologic Etiologies in Chinese Children with Pituitary Stalk Thickening Open
Background: With the increasing use of magnetic resonance imaging (MRI) in the evaluation of children with endocrine disorders, pituitary stalk thickening (PST) poses a clinical conundrum due to the potential for underlying neoplasms and c…
View article: A Chinese girl with delayed puberty due to 17α-hydroxylase deficiency: the diagnosis, treatment and monitoring approach
A Chinese girl with delayed puberty due to 17α-hydroxylase deficiency: the diagnosis, treatment and monitoring approach Open
Summary 17α-hydroxylase deficiency (17α-OHD) is a rare form of congenital adrenal hyperplasia. We report the case of a teenage girl with 17α-OHD who presented with delayed puberty, hypergonadotropic hypogonadism and hypertension. We illust…
View article: Two Girls With Adrenal Insufficiency and Failing Gonads
Two Girls With Adrenal Insufficiency and Failing Gonads Open
Congenital lipoid adrenal hyperplasia (CLAH) is a rare cause of adrenal insufficiency caused by mutations in the steroidogenic acute regulatory (StAR) gene. Patients classically present with adrenal crisis in early infancy and female exter…
View article: Fibrodysplasia ossificans progressiva in Hong Kong—A case report series
Fibrodysplasia ossificans progressiva in Hong Kong—A case report series Open
Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare condition. The diagnosis could be challenging due to its rarity and non-specific presenting symptoms. However, early diagnosis and appropriate management help in preserving patie…
View article: Obesity in children and adolescents: Overview of the diagnosis and management
Obesity in children and adolescents: Overview of the diagnosis and management Open
Childhood obesity is one of the biggest public health challenges globally. It is associated with various adverse health consequences throughout life. Prevention and early intervention represent the most reasonable and cost‐effective approa…
View article: Rare manifestation of hyperreactio luteinalis: when both the mother and baby girl are virilised
Rare manifestation of hyperreactio luteinalis: when both the mother and baby girl are virilised Open
Hyperreactio luteinalis is a benign, pregnancy-related condition with cystic enlargement of the ovaries and elevated androgen. However, only one-third of patients manifest as maternal virilisation and rarely does it cause fetal virilisatio…
View article: Thirty-Minute Post-load Glucose Could Be a Useful Screening Measure for Abnormal Oral Glucose Tolerance Test Response in Adolescents with Obesity
Thirty-Minute Post-load Glucose Could Be a Useful Screening Measure for Abnormal Oral Glucose Tolerance Test Response in Adolescents with Obesity Open
Addition of 30-minute PG to non-fasting parameters improved the clinical utility in identifying high-risk individuals for abnormal OGTT response.
View article: Diabetic ketoacidosis in children with new-onset type 1 diabetes mellitus: demographics, risk factors and outcome: an 11 year review in Hong Kong
Diabetic ketoacidosis in children with new-onset type 1 diabetes mellitus: demographics, risk factors and outcome: an 11 year review in Hong Kong Open
Objectives Diabetic ketoacidosis (DKA) is a life-threatening complication of type 1 diabetes (T1D). The aim of this study is to analyze the incidence, clinical characteristics, management and outcome of children presenting with DKA in new-…
View article: Dental phenotype in an adolescent with osteogenesis imperfecta type XII
Dental phenotype in an adolescent with osteogenesis imperfecta type XII Open
Mutation in SP7, encoding the osteoblast-specific transcription factor SP7 (also known as osterix), has been described to cause osteogenesis imperfecta (OI) type XII. However, the exact dental phenotype has not been well described. We repo…
View article: Successful transition from insulin to sulphonylurea in a child with neonatal diabetes mellitus diagnosed beyond six months of age due to C42R mutation in the <i>KCNJ11</i> gene
Successful transition from insulin to sulphonylurea in a child with neonatal diabetes mellitus diagnosed beyond six months of age due to C42R mutation in the <i>KCNJ11</i> gene Open
Neonatal diabetes mellitus is a rare monogenic condition affecting 1 in 100,000-300,000 live births. Mutations in the subunits of ATP-sensitive potassium (KATP) channels, which are the central gatekeepers of electrical activity,…
View article: Carboplatin-induced Renal Salt Wasting Syndrome in Paediatric Patients with Intracranial Germ Cell Tumours and Concomitant Diabetes Insipidus
Carboplatin-induced Renal Salt Wasting Syndrome in Paediatric Patients with Intracranial Germ Cell Tumours and Concomitant Diabetes Insipidus Open
We report the first case series of 14 children with intracranial germ cell tumour (iGCT) and concomitant central diabetes insipidus (DI), who developed hyponatremia secondary to renal salt wasting syndrome (RSWS) following the administrati…
View article: Association of Early Nutritional Status With Child Development in the Asia Pacific Region
Association of Early Nutritional Status With Child Development in the Asia Pacific Region Open
HFA, BMI-for-age, and body fat proportion were independently associated with ECD, and these findings suggest that future studies should consider using these parameters to estimate the prevalence of child underdevelopment; nutritional trial…
View article: Review on the Screening of Urine Glucose in School Children and Adolescents With Obesity for Early Diagnosis of Type 2 Diabetes Mellitus in Hong Kong
Review on the Screening of Urine Glucose in School Children and Adolescents With Obesity for Early Diagnosis of Type 2 Diabetes Mellitus in Hong Kong Open
Introduction: Obesity and type 2 diabetes mellitus (T2DM) are growing health concerns. A ten-fold increase of T2DM was noted in the Hong Kong paediatric population from 1997 to 2007. T2DM is often asymptomatic at presentation, but complica…
View article: Who Should Return for an Oral Glucose Tolerance Test? A Proposed Clinical Pathway Based on Retrospective Analysis of 332 Children
Who Should Return for an Oral Glucose Tolerance Test? A Proposed Clinical Pathway Based on Retrospective Analysis of 332 Children Open
Purpose: Fasting plasma glucose (FPG) or oral glucose tolerance test (OGTT) is the traditional diagnostic tool for type 2 diabetes (T2DM). Primary barrier to performing FPG or OGTT in asymptomatic patients is the requirement of fasting, an…
View article: Clinical Utility of 30-Min Postload Plasma Glucose in Paediatric Obesity
Clinical Utility of 30-Min Postload Plasma Glucose in Paediatric Obesity Open
Introduction: Intermediary glucose measurements at other time points in a standard 2-hour oral glucose tolerance test (OGTT) is increasingly being investigated, and a number of studies have demonstated strong predictive value of 1-hour pla…
View article: Who should return for an oral glucose tolerance test? A proposed clinical pathway based on retrospective analysis of 332 children
Who should return for an oral glucose tolerance test? A proposed clinical pathway based on retrospective analysis of 332 children Open
Objectives Fasting plasma glucose or oral glucose tolerance test (OGTT) is the traditional diagnostic tool for type 2 diabetes (T2DM). However, fasting is required and implementation in all overweight/obese subjects is not practical. This …
View article: Impact of COVID-19 Pandemic on Serum Vitamin D Level among Infants and Toddlers: An Interrupted Time Series Analysis and before-and-after Comparison
Impact of COVID-19 Pandemic on Serum Vitamin D Level among Infants and Toddlers: An Interrupted Time Series Analysis and before-and-after Comparison Open
Background: During the coronavirus disease 2019 (COVID-19) pandemic, the implementation of social distancing and home confinement measures may elevate the risk of vitamin D deficiency particularly for infants. This study aimed to quantify …
View article: An Assessment of Risk Factors for Insufficient Levels of Vitamin D during Early Infancy
An Assessment of Risk Factors for Insufficient Levels of Vitamin D during Early Infancy Open
Recent evidence suggests that breastfeeding may increase the risk of vitamin D deficiency in offspring. However, it is unclear whether increased risk results from breastfeeding alone, or whether it is associated together with other risk fa…
View article: Author response for "Incidence and Clinical Characteristics of Paediatric‐onset Type 2 Diabetes in Hong Kong: The Hong Kong Childhood Diabetes Registry 2008 to 2017"
Author response for "Incidence and Clinical Characteristics of Paediatric‐onset Type 2 Diabetes in Hong Kong: The Hong Kong Childhood Diabetes Registry 2008 to 2017" Open
View article: Does obesity persist from childhood to adolescence? A 4-year prospective cohort study of chinese students in Hong Kong
Does obesity persist from childhood to adolescence? A 4-year prospective cohort study of chinese students in Hong Kong Open