Joanne Balsamelli
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View article: Novel Diffuse Midline Glioma‐on‐Chip Recapitulating Tumor Biophysical Microenvironment to Assess the Heterogeneity of Response to Therapies
Novel Diffuse Midline Glioma‐on‐Chip Recapitulating Tumor Biophysical Microenvironment to Assess the Heterogeneity of Response to Therapies Open
Despite significant efforts, Diffuse Midline Gliomas (DMGs) remain incurable. Although promising results are obtained in preclinical studies, most approaches have failed to improve survival in these young patients. In this context, by inte…
View article: Dog allergen-induced asthma in mice: a relevant model of T2low severe asthma with airway remodelling
Dog allergen-induced asthma in mice: a relevant model of T2low severe asthma with airway remodelling Open
View article: Identification of epithelial ciliated cells as the non‐endothelial source of mouse endocan
Identification of epithelial ciliated cells as the non‐endothelial source of mouse endocan Open
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View article: Evaluation of Endocan as a Treatment for Acute Inflammatory Respiratory Failure
Evaluation of Endocan as a Treatment for Acute Inflammatory Respiratory Failure Open
Background: Acute respiratory distress syndrome (ARDS) is a life-threatening condition resulting from acute pulmonary inflammation. However, no specific treatment for ARDS has yet been developed. Previous findings suggest that lung injurie…
View article: NOD2 Signaling Circuitry during Allergen Sensitization Does Not Worsen Experimental Neutrophilic Asthma but Promotes a Th2/Th17 Profile in Asthma Patients but Not Healthy Subjects
NOD2 Signaling Circuitry during Allergen Sensitization Does Not Worsen Experimental Neutrophilic Asthma but Promotes a Th2/Th17 Profile in Asthma Patients but Not Healthy Subjects Open
Nucleotide-binding oligomerization domain 2 (NOD2) recognizes pathogens associated with the development of asthma. Moreover, NOD2 adjuvants are used in vaccine design to boost immune responses. Muramyl di-peptide (MDP) is a NOD2 ligand, wh…
View article: Organic and aqueous extraction of lipids from birch pollen grains exposed to gaseous pollutants
Organic and aqueous extraction of lipids from birch pollen grains exposed to gaseous pollutants Open
View article: Is CCL18 a potential biomarker of type-2 asthma endotypes?
Is CCL18 a potential biomarker of type-2 asthma endotypes? Open
Objective: This exploratory cross-sectional study aimed to evaluate the associations between the chemokine ligand 18 (CCL18) blood level and phenotypic characteristics of asthma.Methods: We evaluated in a sample of 173 asthma…
View article: Polycyclic Aromatic Hydrocarbons Reciprocally Regulate IL-22 and IL-17 Cytokines in Peripheral Blood Mononuclear Cells from Both Healthy and Asthmatic Subjects
Polycyclic Aromatic Hydrocarbons Reciprocally Regulate IL-22 and IL-17 Cytokines in Peripheral Blood Mononuclear Cells from Both Healthy and Asthmatic Subjects Open
Pollution, including polycyclic aromatic hydrocarbons (PAH), may contribute to increased prevalence of asthma. PAH can bind to the Aryl hydrocarbon Receptor (AhR), a transcription factor involved in Th17/Th22 type polarization. These cells…