João Cavaleiro Rufo
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View article: The Impact of War on Asthma, a Systematic Review and Meta‐Analysis: An <scp>EAACI</scp> Task Force Report
The Impact of War on Asthma, a Systematic Review and Meta‐Analysis: An <span>EAACI</span> Task Force Report Open
Wartime events have been followed by an increase in asthma prevalence, which is believed to result from a combination of environmental hazards and psychological trauma. This systematic review and meta‐analysis aimed to investigate this rel…
View article: Movement behaviours, air pollution and health in school-aged children: a cross-sectional study to guide the co-creation of healthier environments – the MOVE-AIR project
Movement behaviours, air pollution and health in school-aged children: a cross-sectional study to guide the co-creation of healthier environments – the MOVE-AIR project Open
Introduction The MOVE-AIR study was designed to explore the moderating role of movement behaviours on the association between air pollutants and health outcomes in Portuguese children. Secondarily, it aims to characterise the settings (bot…
View article: EXPOSURE LIMIT VALUE TO RESPIRABLE CRYSTALLINE SILICA – A SYSTEMATIC REVIEW
EXPOSURE LIMIT VALUE TO RESPIRABLE CRYSTALLINE SILICA – A SYSTEMATIC REVIEW Open
Background: Silicosis is a worldwide occupational fibrotic respiratory disease caused by inhaling respirable crystalline silica. There is a lack of knowledge about the limiting value of silica exposure in work labor or environment and comp…
View article: Movement behaviours, air pollution and health in school-aged children: a cross-sectional study to guide the co- creation of healthier environments - The MOVE-AIR Project
Movement behaviours, air pollution and health in school-aged children: a cross-sectional study to guide the co- creation of healthier environments - The MOVE-AIR Project Open
The MOVE-Air study was designed to explore the role of movement behaviours on the association between air pollutants and health outcomes in Portuguese children. Secondarily, it aims to characterize the settings (both indoor and outdoor) wh…
View article: Polymorphisms and haplotypes of <i>TOLLIP</i> and <i>MUC5B</i> are associated with susceptibility and survival in patients with fibrotic hypersensitivity pneumonitis
Polymorphisms and haplotypes of <i>TOLLIP</i> and <i>MUC5B</i> are associated with susceptibility and survival in patients with fibrotic hypersensitivity pneumonitis Open
These findings suggest that TOLLIP and MUC5B variants and haplotypes may serve as valuable tools for risk assessment and prognosis in fibrotic hypersensitivity pneumonitis, potentially contributing to its patient stratification, and…
View article: Does the Mediterranean Dietary Pattern Promote Lower Sodium Urinary Excretion in Children?
Does the Mediterranean Dietary Pattern Promote Lower Sodium Urinary Excretion in Children? Open
An adequate sodium intake is related to various health benefits. Parallelly, the Mediterranean diet (MD) is a dietary pattern known for its many positive impacts on health. Nonetheless, the association between adherence to the MD and sodiu…
View article: Mediterranean Diet and Airway Inflammation in School-Aged Children
Mediterranean Diet and Airway Inflammation in School-Aged Children Open
There seems to exist an intricate relationship between airway inflammation, body mass index (BMI), and diet. The intake of specific foods or food groups has been suggested to suppress the oxidative stress and inflammatory processes that ch…
View article: Diet quality, asthma and airway inflammation in school-aged children
Diet quality, asthma and airway inflammation in school-aged children Open
Background. Asthma is a major public health problem, with increasing prevalence in most countries, particularly among children. Poor dietary quality is also increasing in children, and evidence of the overall quality of children's f…
View article: Diet and Asthma: A Narrative Review
Diet and Asthma: A Narrative Review Open
Asthma is a chronic respiratory disease that impacts millions of people worldwide. Recent studies suggest that diet may play a role in asthma pathophysiology. Several dietary factors have been recognized as potential contributors to the de…
View article: Issue 2 - “Update on adverse respiratory effects of indoor air pollution” Part 1): Indoor air pollution and respiratory diseases: A general update and a Portuguese perspective
Issue 2 - “Update on adverse respiratory effects of indoor air pollution” Part 1): Indoor air pollution and respiratory diseases: A general update and a Portuguese perspective Open
Despite the significant reduction of indoor air pollution effects after the 2008 indoor smoking prohibition in public buildings, studies show that several indoor air parameters are still significantly associated with respiratory health in …
View article: The Influence of Obesity in the Autonomic Nervous System Activity in School-Aged Children in Northern Portugal: A Cross-Sectional Study
The Influence of Obesity in the Autonomic Nervous System Activity in School-Aged Children in Northern Portugal: A Cross-Sectional Study Open
Introduction: Obesity is one of the most prevalent chronic diseases in childhood, being an important public health issue. Excessive weight has been associated with autonomic dysfunction but the evidence in children is scarce. Therefore, th…
View article: Bone and Cytokine Markers Associated With Bone Disease in Systemic Mastocytosis
Bone and Cytokine Markers Associated With Bone Disease in Systemic Mastocytosis Open
View article: Diet Quality and Exhaled Breath Condensate Markers in a Sample of School-Aged Children
Diet Quality and Exhaled Breath Condensate Markers in a Sample of School-Aged Children Open
Exhaled breath condensate (EBC) analysis is a recently developed, non-invasive method used to identify and quantify biomarkers, mainly those coming from the lower respiratory tract. It seems that diet can influence the airway’s inflammatio…
View article: Economic evaluation of biological treatments in patients with severe asthma: a systematic review
Economic evaluation of biological treatments in patients with severe asthma: a systematic review Open
Asthma is a highly prevalent disease, one of the chronic diseases with the highest economic costs; thus, it imposes a high economic burden on society, the healthcare system, patients, and third-party payers. Contrary to this study, until n…
View article: Diagnosis of pathological conditions through electronic nose analysis of urine samples: a systematic review and meta-analysis
Diagnosis of pathological conditions through electronic nose analysis of urine samples: a systematic review and meta-analysis Open
Currently available urinalysis methods are often applied for screening and monitoring of several pathologies. However, traditionally analyzed biomarkers in urinalysis still lack sensitivity and specificity to accurately diagnose some disea…
View article: Environmental inequality: air pollution and asthma in children
Environmental inequality: air pollution and asthma in children Open
Whether you benefit from high-quality urban environments, such as those rich in green and blue spaces, that may offer benefits to allergic and respiratory health depends on where you live and work. Environmental inequality, therefore, resu…
View article: Allergen immunotherapy for asthma prevention: A systematic review and meta‐analysis of randomized and non‐randomized controlled studies
Allergen immunotherapy for asthma prevention: A systematic review and meta‐analysis of randomized and non‐randomized controlled studies Open
Background Allergen immunotherapy (AIT) is a disease‐modifying treatment for IgE‐mediated diseases. Randomized controlled trials (RCTs) support AIT's potential role in asthma prevention but evidence from non‐randomized studies of intervent…
View article: Dietary Acid Load Modulation of Asthma-Related miRNAs in the Exhaled Breath Condensate of Children
Dietary Acid Load Modulation of Asthma-Related miRNAs in the Exhaled Breath Condensate of Children Open
Individual nutrients and bioactive compounds have been implicated in the expression of microRNAs (miRNAs), which are related to inflammation and asthma. However, evidence about the impact of diet is scarce. Therefore, we aimed to assess th…
View article: Association between Land Use Mix and Respiratory Symptoms and Asthma in Children from the Generation XXI Birth Cohort
Association between Land Use Mix and Respiratory Symptoms and Asthma in Children from the Generation XXI Birth Cohort Open
View article: AlergiaPT: A Portuguese media campaign to inspire people with allergies to make a positive change in their life
AlergiaPT: A Portuguese media campaign to inspire people with allergies to make a positive change in their life Open
Allergic diseases comprise a significant cause of morbidity worldwide and a substantial burden on the health and medical systems of both developed and emerging economies. Although highly prevalent, relatively severe, and largely impactful …
View article: Cost-effectiveness analysis of grass pollen specific immunotherapy in children with allergic rhinitis compared to the standard of care symptomatic treatment in Portugal
Cost-effectiveness analysis of grass pollen specific immunotherapy in children with allergic rhinitis compared to the standard of care symptomatic treatment in Portugal Open
Background. Cost-effectiveness studies evaluating allergen immunotherapy (AIT) in children are scarce. We aim to compare the cost-effectiveness of subcutaneous (SCIT) and sublingual immunotherapy (SLIT) against standard-of-care (SOC…
View article: Associações entre a exposição a espaços verdes e o desenvolvimento de asma e doença alérgica em ambientes urbanos: Da coerência à controvérsia científica
Associações entre a exposição a espaços verdes e o desenvolvimento de asma e doença alérgica em ambientes urbanos: Da coerência à controvérsia científica Open
A exposição ao ambiente urbano tem sido associada ao desenvolvimento de asma e doença alérgica. No entanto, as associações encontradas ainda geram controvérsia, com alguns estudos a indicarem os espaços verdes como protetores no desenvolvi…
View article: Childhood asthma and land‐use characteristics in school and residential neighborhoods: A decision tree learning approach
Childhood asthma and land‐use characteristics in school and residential neighborhoods: A decision tree learning approach Open
Growing urbanization imposes a huge pressure on environment and physical landscape.3][4] Yet, given that children spend large periods of time at home and at school, whether and how different land-use characteristics of both neighborhoods a…
View article: Increasing Vegetable Diversity Consumption Impacts the Sympathetic Nervous System Activity in School-Aged Children
Increasing Vegetable Diversity Consumption Impacts the Sympathetic Nervous System Activity in School-Aged Children Open
Evidence about the impact of vegetable and fruit diversity consumption on the autonomic nervous system (ANS) functioning is scarce. In this cross-sectional study (513 participants, 49.9% girls aged 7 to 12 years), we evaluated the associat…
View article: Bacterial Contamination in Health Care Centers: Differences between Urban and Rural Settings
Bacterial Contamination in Health Care Centers: Differences between Urban and Rural Settings Open
This study aims to assess the airborne bioburden of rural and urban Portuguese Primary Health Care Centers (PHCC) using active and passive sampling methods and identify the potential differences in airborne microbiota between both environm…
View article: The Influence of Eating at Home on Dietary Diversity and Airway Inflammation in Portuguese School-Aged Children
The Influence of Eating at Home on Dietary Diversity and Airway Inflammation in Portuguese School-Aged Children Open
Considering the negative impact of a lack of dietary diversity on children’s nutritional status, we aimed to describe dietary variety according to eating at home frequency and assessed its association with respiratory outcomes in school-ag…
View article: Effects of Exercise on the Skin Epithelial Barrier of Young Elite Athletes-Swimming Comparatively to Non-Water Sports Training Session
Effects of Exercise on the Skin Epithelial Barrier of Young Elite Athletes-Swimming Comparatively to Non-Water Sports Training Session Open
The benefits of swimming have been extensively assessed. However, swimming pools contain chlorine and other irritating chemicals that may induce contact dermatitis. To evaluate the effect of a swimming training session on transepidermal wa…
View article: The association between fungi exposure and hypersensitivity pneumonitis: a systematic review
The association between fungi exposure and hypersensitivity pneumonitis: a systematic review Open
A systematic review of published studies focused on the association between hypersensitivity pneumonitis (HP) and fungi exposure was conducted on PubMed, following PRISMA guidelines for systematic reviews. A total of 14 studies met the inc…
View article: Author response for "Higher diversity of vegetable consumption is associated with less airway inflammation and prevalence of asthma in school‐aged children"
Author response for "Higher diversity of vegetable consumption is associated with less airway inflammation and prevalence of asthma in school‐aged children" Open
View article: Evaluation of urinary volatilome in high level elite swimmers
Evaluation of urinary volatilome in high level elite swimmers Open