João Batista Fernandes
YOU?
Author Swipe
View article: Considerations on the Oropouche fever and the use of computational methods in the study of viral molecular protein targets
Considerations on the Oropouche fever and the use of computational methods in the study of viral molecular protein targets Open
The disease caused by the Oropouche virus has been on the rise in countries such as Brazil. Currently, there are no antiviral therapies or vaccines available for treating this viral infection and few studies of Oropouche proteins are avail…
View article: Metabolomic Profiling of Citrus Grafts Challenged by <i>Phytophthora citrophthora</i> : Using the Same Samples Previously Analyzed for Epigenetic Responses
Metabolomic Profiling of Citrus Grafts Challenged by <i>Phytophthora citrophthora</i> : Using the Same Samples Previously Analyzed for Epigenetic Responses Open
Phytophthora citrophthora infection severely affects citrus crops, demanding improved diagnostic and control strategies. In a previous study, epigenetic responses, including DNA methylation patterns, were analyzed in grafted citrus …
View article: Development of Xanthyletin-Loaded Nanoparticles for the Control of Leucoagaricus gongylophorus
Development of Xanthyletin-Loaded Nanoparticles for the Control of Leucoagaricus gongylophorus Open
This study describes the development, characterization and in vitro evaluation of poly(ε-caprolactone) (PCL) nanoparticles loaded with xanthyletin for the control of Atta sexdens rubropilosa through the inhibition of its symbiotic fungus L…
View article: Chemical and Mineralogical Characterization of Waste from Abandoned Copper and Manganese Mines in the Iberian Pyrite Belt, Portugal: A First Step Towards the Waste-to-Value Recycling Process
Chemical and Mineralogical Characterization of Waste from Abandoned Copper and Manganese Mines in the Iberian Pyrite Belt, Portugal: A First Step Towards the Waste-to-Value Recycling Process Open
This study examines the chemical and mineralogical composition of waste materials from abandoned copper and manganese mines in the Iberian Pyrite Belt, Portugal, as a first step toward their potential recycling for critical and strategic r…
View article: Unlocking the Secondary Critical Raw Material Potential of Historical Mine Sites, Lousal Mine, Southern Portugal
Unlocking the Secondary Critical Raw Material Potential of Historical Mine Sites, Lousal Mine, Southern Portugal Open
A steady supply of mineral raw materials is vital for the transition to a low-carbon, circular economy. The number of active mines in Europe has severely declined over the last century and half, giving rise to many abandoned mining waste s…
View article: Predicting rupture risk in cerebral arteriovenous malformations – how universal are current scores?
Predicting rupture risk in cerebral arteriovenous malformations – how universal are current scores? Open
View article: Phytochemical Investigation on Trichilia Elegans a. Juss (Meliaceae) and its Chemotaxonomic Significance
Phytochemical Investigation on Trichilia Elegans a. Juss (Meliaceae) and its Chemotaxonomic Significance Open
View article: Análise de Dados de Metabolômica em Produtos Naturais: uma Revisão-Tutorial
Análise de Dados de Metabolômica em Produtos Naturais: uma Revisão-Tutorial Open
The incredible natural diversity that we can admire at different ecosystems is a result of genetic combinations along with complex metabolic reactions.For centuries, mankind has learned from nature and used its resources to improve the qua…
View article: Biodegradation of the Antibiotic Doxycycline by Bacteria from the Gastrointestinal Tract of Cucurbit Beetles (Diabrotica speciosa)
Biodegradation of the Antibiotic Doxycycline by Bacteria from the Gastrointestinal Tract of Cucurbit Beetles (Diabrotica speciosa) Open
Antibiotics can contaminate the environment as a result of improper disposal. The induction of doxycycline in the environment could give rise to lineages of the cucurbit beetle Diabrotica speciosa containing resistant endosymbiotic microor…
View article: MALDI-TOF Mass Spectrometry for the Diagnosis of Citrus Canker Caused by Xanthomonas citri subsp. citri
MALDI-TOF Mass Spectrometry for the Diagnosis of Citrus Canker Caused by Xanthomonas citri subsp. citri Open
Citrus canker, caused by the bacterium Xanthomonas citri subsp. citri (Xcc), is a disease that causes serious problems to the global citrus industry. Matrix-Assisted Laser Desorption/Ionization Time-of-Flight (MALDI-TOF) Mass Spectrometry …
View article: Exploring chemical diversity in Glycine max cultivars: A multivariate approach in the search for bioactive compounds against Spodoptera cosmioides
Exploring chemical diversity in Glycine max cultivars: A multivariate approach in the search for bioactive compounds against Spodoptera cosmioides Open
Soybean crop is regulated by abiotic and biotic stresses with great potential in reducing grain yield and quality. The selection of resistant cultivars is a promising approach for mitigating these damages. We evaluated the chemical profile…
View article: The Symbiotic Fungus Leucoagaricus gongylophorus (Möller) Singer (Agaricales, Agaricaceae) as a Target Organism to Control Leaf-Cutting Ants
The Symbiotic Fungus Leucoagaricus gongylophorus (Möller) Singer (Agaricales, Agaricaceae) as a Target Organism to Control Leaf-Cutting Ants Open
Atta and Acromyrmex are the main genera of leaf-cutting ants present in North and South America, causing extensive damage to agroforestry. Control of the ants requires high handling costs with few effective methods available to decrease th…
View article: Valorization of Hesperidin from Citrus Residues: Evaluation of Microwave-As
Valorization of Hesperidin from Citrus Residues: Evaluation of Microwave-As Open
The aim of the current study was the valorization of hesperidin, the dominant flavonoid in citrus processing waste, by microwave-assisted synthesis of hesperidin-Mg complex, improving its antioxidant activity and insecticidal potential. He…
View article: INSECTICIDAL AND FUNGICIDAL ACTIVITY OF A MAGNESIUM COMPOUND CONTAINING ISOVANILLIC ACID AGAINST LEAF-CUTTING ANT AND ITS SYMBIOTIC FUNGUS
INSECTICIDAL AND FUNGICIDAL ACTIVITY OF A MAGNESIUM COMPOUND CONTAINING ISOVANILLIC ACID AGAINST LEAF-CUTTING ANT AND ITS SYMBIOTIC FUNGUS Open
Pesticides offer a simple, cost-effective solution to ensure food supplies for a growing world population. However, their environmental performance needs improvement if pesticides are to continue contributing importantly. This study explor…
View article: Quality Control for Lignin and Gelatin Microcapsules Loaded with Orange Essential Oil
Quality Control for Lignin and Gelatin Microcapsules Loaded with Orange Essential Oil Open
Sustainable natural product-based microstructured systems and biopolymers are strong candidates for use in crop protection. Lignin and gelatin microcapsules loaded with orange essential oil were developed with spray-drying in order to enha…
View article: Encapsulation of B. bassiana in Biopolymers: Improving Microbiology of Insect Pest Control
Encapsulation of B. bassiana in Biopolymers: Improving Microbiology of Insect Pest Control Open
The fungus Beauveria bassiana is widely used for pest control; however, biostability and dispersion for broth pulverization are limiting factors for its application in the field. In this context, formulation techniques such as microencapsu…
View article: Flavonoids and Insecticidal Activity Against Spodoptera frugiperda of Myrsine coriacea (Primulaceae)
Flavonoids and Insecticidal Activity Against Spodoptera frugiperda of Myrsine coriacea (Primulaceae) Open
This study was conducted to evaluate the insecticidal effects of Myrsine coriacea (Primulaceae) against one of the main pests of maize, the fall armyworm (Spodoptera frugiperda), as well as performing the phytochemical study of M. coriacea…
View article: Evaluation of Lignins of Trunk and Roots from Citrus sinensis L. Osbeck: A Large Available Brazilian Biomass
Evaluation of Lignins of Trunk and Roots from Citrus sinensis L. Osbeck: A Large Available Brazilian Biomass Open
Citrus biomass is a source of biobased products and presents extensive chemical diversity. Among the structural macromolecules, lignins have been used in resins, bioplastics, and nanoencapsulation. Brazil has a large source of lignins, whi…
View article: New Synthetic Quinolines as Cathepsin K Inhibitors
New Synthetic Quinolines as Cathepsin K Inhibitors Open
Cathepsin K is a papain-like cysteine protease and is responsible for collagen degradation in bone tissue and thus represents an important target for the development of new therapies for treating diseases such as osteoporosis. Quinolines a…
View article: Biochemical and morphological biomarker responses in the gills of a Neotropical fish exposed to a new flavonoid metal-insecticide
Biochemical and morphological biomarker responses in the gills of a Neotropical fish exposed to a new flavonoid metal-insecticide Open
The flavonoid metal-insecticide [Mg(hesp)2(phen)], denominated MgHP, has high potential for controlling agricultural pests. If applied in large scale, it may reach aquatic ecosystems and be harmful to the biota. This study evalu…
View article: Cocultivation as a toll to understand the communication among the leafcutting ants symbionts
Cocultivation as a toll to understand the communication among the leafcutting ants symbionts Open
View article: To separate or not to separate: what is necessary and enough for a green and sustainable extraction of bioactive compounds from Brazilian citrus waste
To separate or not to separate: what is necessary and enough for a green and sustainable extraction of bioactive compounds from Brazilian citrus waste Open
Increasing demands to obtain chemicals via greener and more sustainable materials and processes introduces concepts that should be considered and applied from lab to larger scales. Obtaining bioactive chemicals from agro-industrial non-foo…
View article: Avocado kernels, an industrial residue: a source of compounds with insecticidal activity against silverleaf whitefly
Avocado kernels, an industrial residue: a source of compounds with insecticidal activity against silverleaf whitefly Open
View article: Evaluation of the microencapsulation of orange essential oil in biopolymers by using a spray-drying process
Evaluation of the microencapsulation of orange essential oil in biopolymers by using a spray-drying process Open
View article: Green asymmetric synthesis of epoxypeptidomimetics and evaluation as human cathepsin K inhibitors
Green asymmetric synthesis of epoxypeptidomimetics and evaluation as human cathepsin K inhibitors Open
View article: Mycotoxins from Fusarium proliferatum: new inhibitors of papain-like cysteine proteases
Mycotoxins from Fusarium proliferatum: new inhibitors of papain-like cysteine proteases Open
View article: Synthesis, Characterization, and Low-Toxicity Study of a Magnesium(II) Complex Containing an Isovanillate Group
Synthesis, Characterization, and Low-Toxicity Study of a Magnesium(II) Complex Containing an Isovanillate Group Open
The beneficial effect of polyphenols and magnesium(II) against oxidative stress motivated our research group to explore the antioxidant activity of phenMgIso, an aqueous soluble magnesium(II) complex containing 1,10-phenanthroline (phen) a…
View article: Antimicrobial activity of isolated compounds and semisynthetic derivatives from Miconia ferruginata
Antimicrobial activity of isolated compounds and semisynthetic derivatives from Miconia ferruginata Open
This study evaluated the antimicrobial activity of isolated compounds and semisynthetic derivatives from Miconia ferruginata (Melastomataceae) against five microorganisms: Staphylococcus aureus (ATCC 25923), Escherichia coli (ATCC 25922), …
View article: New Synthetic Quinolines as Cathepsin K Inhibitors
New Synthetic Quinolines as Cathepsin K Inhibitors Open
Cathepsin K is a papain-like cysteine protease and is responsible for collagen degradation in bone tissue and thus represents an important target for the development of new therapies for treating diseases such as osteoporosis.Quinolines ar…
View article: Isolated Compounds and Semi-Synthetic Derivatives from Miconia ferruginata as Inhibitors of Cathepsins K and B and their Cytotoxic Evaluation
Isolated Compounds and Semi-Synthetic Derivatives from Miconia ferruginata as Inhibitors of Cathepsins K and B and their Cytotoxic Evaluation Open
Resumo: O gênero Miconia, pertencente à família Melastomataceae, é amplamente distribuído na América tropical.Compostos isolados e derivados semissintéticos das folhas de Miconia ferruginata foram avaliados quanto à citotoxicidade em linha…