João Pedro Baptista
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View article: Are contemporary antifungal doses sufficient for critically ill patients? Outcomes from an international, multicenter pharmacokinetics study for Screening Antifungal Exposure in Intensive Care Units—the SAFE-ICU study
Are contemporary antifungal doses sufficient for critically ill patients? Outcomes from an international, multicenter pharmacokinetics study for Screening Antifungal Exposure in Intensive Care Units—the SAFE-ICU study Open
View article: Cutaneous mucormycosis in a young immunocompetent trauma patient: a case report
Cutaneous mucormycosis in a young immunocompetent trauma patient: a case report Open
Introduction: Mucormycosis, a rare and life-threatening infection, is caused by microorganisms of the Mucorales order. It affects almost exclusively immunocompromised and diabetic patients, requiring extensive surgical debridement and prol…
View article: What is New in Augmented Renal Clearance in Septic Patients?
What is New in Augmented Renal Clearance in Septic Patients? Open
Purpose of Review In this narrative review encompassing relevant scientific publications regarding critically ill patients in the last 5 years, we discuss key questions regarding the concept, pathophysiology, identification, epidemiology, …
View article: Renal function in the ICU: always look both ways before initiating venous thromboprophylaxis
Renal function in the ICU: always look both ways before initiating venous thromboprophylaxis Open
View article: A protocol for an international, multicentre pharmacokinetic study for Screening Antifungal Exposure in Intensive Care Units: The SAFE-ICU study
A protocol for an international, multicentre pharmacokinetic study for Screening Antifungal Exposure in Intensive Care Units: The SAFE-ICU study Open
This study will describe whether contemporary antifungal drug dosing achieves drug exposures associated with optimal outcomes. Data will also be used for the development of antifungal dosing algorithms for critically ill patients. Optimise…
View article: Corticosteroid Therapy in Severe Cases of Pneumonia Caused by SARS-CoV-2
Corticosteroid Therapy in Severe Cases of Pneumonia Caused by SARS-CoV-2 Open
We present a case of severe pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a 63-year-old woman needing venous oxygenation by an extracorporeal membrane. Given the difficult clinical resolution with pers…
View article: Phlegmasia cerulea dolens: a swelling, cyanosis and discolouration of the extremity in the ICU
Phlegmasia cerulea dolens: a swelling, cyanosis and discolouration of the extremity in the ICU Open
Phlegmasia cerulea dolens is a rare entity that causes critical limb ischaemia, which may lead to amputation of the limb and may be life-threatening. Here, we describe a case of a healthy man in his 50s with multiple trauma who was transfe…
View article: Major adverse cardiac events in critically ill COVID-19 patients
Major adverse cardiac events in critically ill COVID-19 patients Open
Background Critically ill patients hospitalized with COVID-19 are at high risk of developing major adverse cardiac events (MACE). Purpose This study aimed to identify independent predictors of MACE after intensive care unit (ICU) admission…
View article: Atrial fibrillation in COVID-19 patients admitted to an intensive care unit: prevalence and prognosis
Atrial fibrillation in COVID-19 patients admitted to an intensive care unit: prevalence and prognosis Open
Background The association between atrial fibrillation (AF) and prognosis has been studied in non-COVID-19 patients, but few studies reflect the reality of critically ill COVID-19 patients admitted to a general intensive care unit (ICU). P…
View article: Admission NT-proBNP and outcomes in critically ill COVID-19 patients
Admission NT-proBNP and outcomes in critically ill COVID-19 patients Open
Funding Acknowledgements Type of funding sources: None. Background/Introduction The association between NT-proBNP levels and prognosis in critically ill non-COVID-19 patients and non-critically ill patients has been studied, but few studie…
View article: Prognostic value of cardiac troponin in critically ill COVID-19 patients
Prognostic value of cardiac troponin in critically ill COVID-19 patients Open
Funding Acknowledgements Type of funding sources: None. Background/Introduction Among patients with COVID-19, there is a high prevalence of cardiovascular disease and myocardial injury from the infection, especially in critically ill patie…
View article: New-onset atrial fibrillation predicts poor prognosis in critically ill COVID-19 patients
New-onset atrial fibrillation predicts poor prognosis in critically ill COVID-19 patients Open
Funding Acknowledgements Type of funding sources: None. Background/Introduction The association between new-onset atrial fibrillation (AF) and prognosis in critically ill non-COVID-19 patients and non-critically ill patients has been studi…
View article: Cardiovascular disease in critically ill COVID-19 patients
Cardiovascular disease in critically ill COVID-19 patients Open
Funding Acknowledgements Type of funding sources: None. Background/Introduction It is now well known that patients with COVID-19 have a high prevalence of cardiovascular disease. COVID-19 is also associated with a substantial degree of car…
View article: Prognostic value of hyperlactatemia in infected patients admitted to intensive care units: a multicenter study
Prognostic value of hyperlactatemia in infected patients admitted to intensive care units: a multicenter study Open
View article: Valor prognóstico da hiperlactatemia em pacientes admitidos com infecção em unidades de terapia intensiva: estudo multicêntrico
Valor prognóstico da hiperlactatemia em pacientes admitidos com infecção em unidades de terapia intensiva: estudo multicêntrico Open
Blood lactate levels correlate independently with in-hospital mortality for moderate and severe degrees of hyperlactatemia.
View article: Prognostic value of hyperlactatemia in infected patients admitted to intensive care units: a multicenter study
Prognostic value of hyperlactatemia in infected patients admitted to intensive care units: a multicenter study Open
Objective: To evaluate the influence of patient characteristics on hyperlactatemia in an infected population admitted to intensive care units and the influence of hyperlactatemia severity on hospital mortality. Methods: A post hoc analysis…
View article: Prognostic value of hyperlactatemia in infected patients admitted to intensive care units: a multicenter study
Prognostic value of hyperlactatemia in infected patients admitted to intensive care units: a multicenter study Open
Objective: To evaluate the influence of patient characteristics on hyperlactatemia in an infected population admitted to intensive care units and the influence of hyperlactatemia severity on hospital mortality.Methods: A post hoc analysis …
View article: Life-threatening complications of Ludwig’s angina: a series of cases in a developed country
Life-threatening complications of Ludwig’s angina: a series of cases in a developed country Open
Ludwig’s angina is a deep neck space infection defined as a rapidly progressive bilateral cellulitis of the submandibular space. In spite of being an uncommon entity in developed countries and the reduction of mortality and morbidity due t…
View article: Urinary Creatinine Clearance and Pharmacokinetics Studies: If We Can Measure It, Why Do We Estimate It?
Urinary Creatinine Clearance and Pharmacokinetics Studies: If We Can Measure It, Why Do We Estimate It? Open
View article: Disseminated Strongyloides stercoralis Infection Associated with Endogenous Hypercortisolism – A Case Report
Disseminated Strongyloides stercoralis Infection Associated with Endogenous Hypercortisolism – A Case Report Open
Patients with Strongyloides stercoralis infections are usually asymptomatic but massive hyperinfection may occur in patients with diseases associated with abnormal cell-mediated immunity or receiving immunosuppressive therapy. The authors …
View article: Hospital-Acquired Pneumonia in a Multipurpose Intensive Care Unit: One-Year Prospective Study
Hospital-Acquired Pneumonia in a Multipurpose Intensive Care Unit: One-Year Prospective Study Open
Introduction: Hospital-acquired pneumonia continues to be a frequent complication in the intensive care unit and an important cause of admission in the intensive care unit. The aim of our study was to evaluate the demography, incidence, ri…
View article: Attainment of therapeutic vancomycin level within the first 24 h: Authors' response
Attainment of therapeutic vancomycin level within the first 24 h: Authors' response Open
View article: Pathophysiology of acute fibrinous and organizing pneumonia – Clinical and morphological spectra
Pathophysiology of acute fibrinous and organizing pneumonia – Clinical and morphological spectra Open
Acute Fibrinous and Organizing Pneumonitis (AFOP) is a disease with histopathological pattern characterized by the presence of intra-alveolar fibrin in the form of fibrin "balls" and organizing pneumonia represented by inflammatory myofibr…
View article: Severe ketorolac-induced asthma diagnosed by chest computed tomography
Severe ketorolac-induced asthma diagnosed by chest computed tomography Open
Aspirin-exacerbated respiratory disease (AERD) affects 15% of severe asthmatics and drug reactions cause 200,000 annual deaths in Europe. A 65-year-old lady presented to emergency for progressive abdominal pain. Her medical history include…
View article: Impact of antibiotic therapy in severe community-acquired pneumonia: Data from the Infauci study
Impact of antibiotic therapy in severe community-acquired pneumonia: Data from the Infauci study Open
View article: P1.10: Follow-Up on Results of a Multidisciplinary Team in the Management of Non-Small Cell Lung Cancer in a Developing Country
P1.10: Follow-Up on Results of a Multidisciplinary Team in the Management of Non-Small Cell Lung Cancer in a Developing Country Open
View article: MP724RENAL TRANSPLANTATION IN AN INTENSIVE CARE UNIT: AN 11-YEAR PORTRAIT
MP724RENAL TRANSPLANTATION IN AN INTENSIVE CARE UNIT: AN 11-YEAR PORTRAIT Open
View article: Renal transplantation in an intensive care unit: an 11-year portrait
Renal transplantation in an intensive care unit: an 11-year portrait Open