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View article: Safe Water Is Rapidly Becoming a Private Good in the United States
Safe Water Is Rapidly Becoming a Private Good in the United States Open
View article: Human fecal markers in environmental waters and association with indicators of human and rodent infections in urban Salvador, Bahia, Brazil
Human fecal markers in environmental waters and association with indicators of human and rodent infections in urban Salvador, Bahia, Brazil Open
This study explores the use of human mitochondrial DNA (mtDNA) markers, specifically hCYTB484, as fecal source tracking (FST) tools for environmental surveillance in a high-density, low-income community in Salvador, Bahia, Brazil. Here, we…
View article: Targeted pathogen profiling of ancient feces reveals common enteric infections in the Rio Zape Valley, 725–920 CE
Targeted pathogen profiling of ancient feces reveals common enteric infections in the Rio Zape Valley, 725–920 CE Open
DNA analysis of ancient, desiccated feces - termed paleofeces - can unlock insights into the lives of ancient peoples, including through examination of the gut microbiome and identification of specific pathogens and parasites. We collected…
View article: Targeted pathogen profiling of ancient feces reveals common enteric infections in the Rio Zape Valley, 725–920 CE
Targeted pathogen profiling of ancient feces reveals common enteric infections in the Rio Zape Valley, 725–920 CE Open
DNA analysis of ancient, desiccated feces – termed paleofeces – can unlock insights into the lives of ancient peoples, including through examination of the gut microbiome and identification of specific pathogens and parasites. We collected…
View article: Human fecal markers in environmental waters and association with indicators of human and rodent infections in urban Salvador, Bahia, Brazil
Human fecal markers in environmental waters and association with indicators of human and rodent infections in urban Salvador, Bahia, Brazil Open
This study explores the use of human mitochondrial DNA (mtDNA) markers, specifically hCYTB484, as fecal source tracking (FST) tools for environmental surveillance in a high-density, low-income community in Salvador, Bahia, Brazil. Here, we…
View article: Variability of enteric pathogen infections by season and meteorological conditions in a low-income, urban setting in Mozambique
Variability of enteric pathogen infections by season and meteorological conditions in a low-income, urban setting in Mozambique Open
Enteric pathogen transmission is influenced by seasonality and meteorological conditions, yet these relationships are not well understood. We investigated the relationships between (1) season, (2) heavy rainfall events, and (3) temperature…
View article: Associations between Fecal Contamination of the Household Environment and Enteric Pathogen Detection in Children Living in Maputo, Mozambique
Associations between Fecal Contamination of the Household Environment and Enteric Pathogen Detection in Children Living in Maputo, Mozambique Open
Environmental exposure to enteric pathogens is generally assessed using fecal indicators but relationships between markers of fecal contamination and actual exposure to enteric pathogens remain poorly characterized. We investigated whether…
View article: Unreliable Results of a Commercial Real-Time Water Quality Sensor in Identifying Fecal Contamination of Drinking Water
Unreliable Results of a Commercial Real-Time Water Quality Sensor in Identifying Fecal Contamination of Drinking Water Open
Low-cost technologies are increasingly being explored and marketed as capable of filling gaps in global water quality monitoring (WQM), especially in resource-limited settings. This study evaluates a commercially available, low-cost triboe…
View article: A study protocol for an interrupted time series analysis and pre-post surveys to assess the effects a community-wide sanitation system on environmental contamination, infection risk, and well-being in Alabama’s Black Belt
A study protocol for an interrupted time series analysis and pre-post surveys to assess the effects a community-wide sanitation system on environmental contamination, infection risk, and well-being in Alabama’s Black Belt Open
Introduction Rural sanitation deficits in the United States represent an important source of non-point source pollution and may present risks to public health. We propose an interrupted time series analysis to measure the effect of a town-…
View article: The Impact of Urban Water Supply Improvements on Infant Enteric Pathogen Infection, Diarrhea, and Growth: Results from the PAASIM Matched Cohort Study
The Impact of Urban Water Supply Improvements on Infant Enteric Pathogen Infection, Diarrhea, and Growth: Results from the PAASIM Matched Cohort Study Open
We conducted a matched-control study in Beira, Mozambique to assess the impact of neighborhood-level urban water system improvements on child health and enteric infections. The intervention did not impact infection with bacteria (aRR 0.97,…
View article: Viral adsorption to Moore swabs in passive wastewater sampling
Viral adsorption to Moore swabs in passive wastewater sampling Open
Moore swabs have been used extensively for passive sampling in wastewater surveillance, typically yielding presence/absence information for targets of interest. Quantitative analysis of Moore swab data is only possible if target uptake is …
View article: Environmental pathogen hazards reveal need for improved sanitation infrastructure in Alabama's Black Belt
Environmental pathogen hazards reveal need for improved sanitation infrastructure in Alabama's Black Belt Open
Many rural communities in Alabama’s Black Belt region lack adequate sanitation resulting in wastewater discharges that may pose risks to residents. To understand the scope of the problem in one community, we conducted three cross-sectional…
View article: Parallel deployment of passive and composite samplers for surveillance and variant profiling of SARS-CoV-2 in sewage
Parallel deployment of passive and composite samplers for surveillance and variant profiling of SARS-CoV-2 in sewage Open
View article: Passive sampling to scale wastewater surveillance of infectious disease: Lessons learned from COVID-19
Passive sampling to scale wastewater surveillance of infectious disease: Lessons learned from COVID-19 Open
View article: Urban water network upgrades improve quality and access to drinking water in the PAASIM matched cohort study in Beira, Mozambique
Urban water network upgrades improve quality and access to drinking water in the PAASIM matched cohort study in Beira, Mozambique Open
Rigorous evaluations of community water supply interventions are necessary to understand their impact on water quality and access. Our study in Beira, Mozambique assessed the impact of water infrastructure improvements in neighborhoods wit…
View article: Associations between Fecal Contamination of the Household Environment and Enteric Pathogen Detection in Children Living in Maputo, Mozambique
Associations between Fecal Contamination of the Household Environment and Enteric Pathogen Detection in Children Living in Maputo, Mozambique Open
Environmental exposure to enteric pathogens is generally assessed using fecal indicators but relationships between markers of fecal contamination and actual exposure to enteric pathogens remain poorly characterized. We investigated whether…
View article: Impact of an Urban Sanitation Intervention on Enteric Pathogen Detection in Soils
Impact of an Urban Sanitation Intervention on Enteric Pathogen Detection in Soils Open
Environmental fecal contamination is common in many low-income cities, contributing to a high burden of enteric infections and associated negative sequelae. To evaluate the impact of a shared onsite sanitation intervention in Maputo, Mozam…
View article: Human fecal contamination of water, soil, and surfaces in households sharing poor-quality sanitation facilities in Maputo, Mozambique
Human fecal contamination of water, soil, and surfaces in households sharing poor-quality sanitation facilities in Maputo, Mozambique Open
View article: Quantitative Microbial Risk Assessment of Pediatric Infections Attributable to Ingestion of Fecally Contaminated Domestic Soils in Low-Income Urban Maputo, Mozambique
Quantitative Microbial Risk Assessment of Pediatric Infections Attributable to Ingestion of Fecally Contaminated Domestic Soils in Low-Income Urban Maputo, Mozambique Open
Rigorous studies of water, sanitation, and hygiene interventions in low- and middle-income countries (LMICs) suggest that children are exposed to enteric pathogens via multiple interacting pathways, including soil ingestion. In 30 compound…
View article: Analysis of Fecal Sludges Reveals Common Enteric Pathogens in Urban Maputo, Mozambique
Analysis of Fecal Sludges Reveals Common Enteric Pathogens in Urban Maputo, Mozambique Open
Sewage surveillance is increasingly used in public health applications: metabolites, biomarkers, and pathogens are detectable in wastewater and can provide useful information about community health. Work on this topic has been limited to w…
View article: Effects of an urban sanitation intervention on childhood enteric infection and diarrhea in Maputo, Mozambique: a controlled before-and-after trial
Effects of an urban sanitation intervention on childhood enteric infection and diarrhea in Maputo, Mozambique: a controlled before-and-after trial Open
We conducted a controlled before-and-after trial to evaluate the impact of an onsite urban sanitation intervention on the prevalence of enteric infection, soil transmitted helminth re-infection, and diarrhea among children in Maputo, Mozam…
View article: A localized sanitation status index as a proxy for fecal contamination in urban Maputo, Mozambique
A localized sanitation status index as a proxy for fecal contamination in urban Maputo, Mozambique Open
Sanitary surveys are used in low- and middle-income countries to assess water, sanitation, and hygiene conditions, but have rarely been compared with direct measures of environmental fecal contamination. We conducted a cross-sectional asse…
View article: Urban Onsite Sanitation Upgrades and Synanthropic Flies in Maputo, Mozambique: Effects on Enteric Pathogen Infection Risks
Urban Onsite Sanitation Upgrades and Synanthropic Flies in Maputo, Mozambique: Effects on Enteric Pathogen Infection Risks Open
Synanthropic filth flies transport enteric pathogens from feces to food, which upon consumption poses an infection risk. We evaluated the effect of an onsite sanitation intervention─including fly control measures─in Maputo, Mozambique, on …
View article: Impacts of an Urban Sanitation Intervention on Fecal Indicators and the Prevalence of Human Fecal Contamination in Mozambique
Impacts of an Urban Sanitation Intervention on Fecal Indicators and the Prevalence of Human Fecal Contamination in Mozambique Open
Fecal source tracking (FST) may be useful to assess pathways of fecal contamination in domestic environments and to estimate the impacts of water, sanitation, and hygiene (WASH) interventions in low-income settings. We measured two nonspec…
View article: Risk factors for early childhood growth faltering in rural Cambodia: a cross-sectional study
Risk factors for early childhood growth faltering in rural Cambodia: a cross-sectional study Open
OBJECTIVE: This study aimed to determine risk factors of growth faltering by assessing childhood nutrition and household water, sanitation, and hygiene (WASH) variables and their association with nutritional status of children under 24 mon…
View article: Higher pathogen load in children from Mozambique vs. USA revealed by comparative fecal microbiome profiling
Higher pathogen load in children from Mozambique vs. USA revealed by comparative fecal microbiome profiling Open
The infant gut microbiome has lifelong implications on health and immunity but there is still limited understanding of the microbiome differences and similarities between children in low- and middle-income countries (LMICs) vs. high-income…
View article: Burden of disease attributable to unsafe drinking water, sanitation, and hygiene in domestic settings: a global analysis for selected adverse health outcomes
Burden of disease attributable to unsafe drinking water, sanitation, and hygiene in domestic settings: a global analysis for selected adverse health outcomes Open
View article: Moving beyond Wastewater: Perspectives on Environmental Surveillance of Infectious Diseases for Public Health Action in Low-Resource Settings
Moving beyond Wastewater: Perspectives on Environmental Surveillance of Infectious Diseases for Public Health Action in Low-Resource Settings Open
Although testing wastewater for public health surveillance has recently received significant attention in the United States, researchers and public health professionals have long realized the tremendous promise of environmental surveillanc…
View article: Systematic Review of Microorganism Removal Performance by Physiochemical Water Treatment Technologies
Systematic Review of Microorganism Removal Performance by Physiochemical Water Treatment Technologies Open
Access to safe drinking water is crucial for public health necessitating the use of effective water treatment processes. We conducted a systematic literature review on microorganism removal by physical treatment processes used in drinking …
View article: Systematic Review of the Microbiological Performance of Household Water Treatment Technologies
Systematic Review of the Microbiological Performance of Household Water Treatment Technologies Open
Household water treatment (HWT) is a prevalent method for improving the safety of drinking-water. We conducted a systematic review of peer-reviewed literature from 1997 to 2021 on microbiological performance of common HWT technologies incl…