Johan Lundin
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View article: Validation of Conformal Prediction in Cervical Atypia Classification
Validation of Conformal Prediction in Cervical Atypia Classification Open
Deep learning based cervical cancer classification can potentially increase access to screening in low-resource regions. However, deep learning models are often overconfident and do not reliably reflect diagnostic uncertainty. Moreover, th…
View article: Comparison of different Lunit INSIGHT CXR software versions when reading chest radiographs for tuberculosis
Comparison of different Lunit INSIGHT CXR software versions when reading chest radiographs for tuberculosis Open
New versions of computer-aided detection (CAD) software for chest X-ray (CXR) interpretation during tuberculosis (TB) screening are regularly released which purport to have incremental performance gains. No studies have independently asses…
View article: AI-Supported Digital Microscopy Diagnostics in Primary Health Care Laboratories: Protocol for a Scoping Review
AI-Supported Digital Microscopy Diagnostics in Primary Health Care Laboratories: Protocol for a Scoping Review Open
Background Digital microscopy combined with artificial intelligence (AI) is increasingly being implemented in health care, predominantly in advanced laboratory settings. However, AI-supported digital microscopy could be especially advantag…
View article: Diagnosis of soil-transmitted helminth infections with digital mobile microscopy and artificial intelligence in a resource-limited setting
Diagnosis of soil-transmitted helminth infections with digital mobile microscopy and artificial intelligence in a resource-limited setting Open
Background Infections caused by soil-transmitted helminths (STHs) are the most prevalent neglected tropical diseases and result in a major disease burden in low- and middle-income countries, especially in school-aged children. Improved dia…
View article: AI-Supported Digital Microscopy Diagnostics in Primary Health Care Laboratories: Protocol for a Scoping Review (Preprint)
AI-Supported Digital Microscopy Diagnostics in Primary Health Care Laboratories: Protocol for a Scoping Review (Preprint) Open
BACKGROUND Digital microscopy combined with artificial intelligence (AI) is increasingly being implemented in health care, predominantly in advanced laboratory settings. However, AI-supported digital microscopy could be especially advanta…
View article: External validation of a deep learning-based algorithm for detection of tall cells in papillary thyroid carcinoma: A multicenter study
External validation of a deep learning-based algorithm for detection of tall cells in papillary thyroid carcinoma: A multicenter study Open
The tall cell subtype (TC-PTC) is an aggressive subtype of papillary thyroid carcinoma (PTC). The TC-PTC is defined as a PTC comprising at least 30% epithelial cells that are three times as tall as they are wide. In practice, this definiti…
View article: A Novel Deep Learning-Based Point-of-Care Diagnostic Method for Detecting Plasmodium falciparum with Fluorescence Digital Microscopy
A Novel Deep Learning-Based Point-of-Care Diagnostic Method for Detecting Plasmodium falciparum with Fluorescence Digital Microscopy Open
Light microscopy assessment of blood smears to detect Plasmodium parasites remains the diagnostic gold standard and allows detection and quantification of the various Plasmodium species while also being more sensitive than rapid diagnostic…
View article: Data from Molecular Subtypes of Breast Cancers Detected in Mammography Screening and Outside of Screening
Data from Molecular Subtypes of Breast Cancers Detected in Mammography Screening and Outside of Screening Open
Purpose: The frequency and significance of gene expression profile-derived molecular subtypes of breast cancers found in mammography screening are unknown.Experimental Design: We identified breast cancers diagnosed in women of any age livi…
View article: Supplementary Data from Molecular Subtypes of Breast Cancers Detected in Mammography Screening and Outside of Screening
Supplementary Data from Molecular Subtypes of Breast Cancers Detected in Mammography Screening and Outside of Screening Open
Supplementary Data from Molecular Subtypes of Breast Cancers Detected in Mammography Screening and Outside of Screening
View article: Supplementary Data from Molecular Subtypes of Breast Cancers Detected in Mammography Screening and Outside of Screening
Supplementary Data from Molecular Subtypes of Breast Cancers Detected in Mammography Screening and Outside of Screening Open
Supplementary Data from Molecular Subtypes of Breast Cancers Detected in Mammography Screening and Outside of Screening
View article: Data from Molecular Subtypes of Breast Cancers Detected in Mammography Screening and Outside of Screening
Data from Molecular Subtypes of Breast Cancers Detected in Mammography Screening and Outside of Screening Open
Purpose: The frequency and significance of gene expression profile-derived molecular subtypes of breast cancers found in mammography screening are unknown.Experimental Design: We identified breast cancers diagnosed in women of any age livi…
View article: Data from Association of Wwox with ErbB4 in Breast Cancer
Data from Association of Wwox with ErbB4 in Breast Cancer Open
WWOX, WW domain-containing oxidoreductase, is a tumor suppressor that is altered in many human cancers, including breast cancer. Wwox interacts with the ErbB4 receptor, reduces nuclear translocation of the cleaved intracellular domain of E…
View article: Data from Association of Wwox with ErbB4 in Breast Cancer
Data from Association of Wwox with ErbB4 in Breast Cancer Open
WWOX, WW domain-containing oxidoreductase, is a tumor suppressor that is altered in many human cancers, including breast cancer. Wwox interacts with the ErbB4 receptor, reduces nuclear translocation of the cleaved intracellular domain of E…
View article: Supplementary Table 1, Figures 1-2 from Association of Wwox with ErbB4 in Breast Cancer
Supplementary Table 1, Figures 1-2 from Association of Wwox with ErbB4 in Breast Cancer Open
Supplementary Table 1, Figures 1-2 from Association of Wwox with ErbB4 in Breast Cancer
View article: Supplementary Table 1, Figures 1-2 from Association of Wwox with ErbB4 in Breast Cancer
Supplementary Table 1, Figures 1-2 from Association of Wwox with ErbB4 in Breast Cancer Open
Supplementary Table 1, Figures 1-2 from Association of Wwox with ErbB4 in Breast Cancer
View article: A deep learning–based algorithm for tall cell detection in papillary thyroid carcinoma
A deep learning–based algorithm for tall cell detection in papillary thyroid carcinoma Open
Introduction According to the World Health Organization, the tall cell variant (TCV) is an aggressive subtype of papillary thyroid carcinoma (PTC) comprising at least 30% epithelial cells two to three times as tall as they are wide. In pra…
View article: The Increase of The Relative Amount of Nodular Calcification In Femoral Plaques is Associated With Milder Lower Extremity Arterial Disease
The Increase of The Relative Amount of Nodular Calcification In Femoral Plaques is Associated With Milder Lower Extremity Arterial Disease Open
Vascular calcification exists in different forms that reflect variable clinical and histological implications. Categories of calcification have not been quantified in relation to the clinical presentation of lower extremity arterial diseas…
View article: Outcome and biomarker supervised deep learning for survival prediction in two multicenter breast cancer series
Outcome and biomarker supervised deep learning for survival prediction in two multicenter breast cancer series Open
A multitask deep learning algorithm supervised by both patient outcome and biomarker status learned features in basic tissue morphology predictive of survival in a nationwide, multicenter series of patients with breast cancer. The algorith…
View article: A proof-of-concept study on mortality prediction with machine learning algorithms using burn intensive care data
A proof-of-concept study on mortality prediction with machine learning algorithms using burn intensive care data Open
Introduction Burn injuries are a common traumatic injury. Large burns have high mortality requiring intensive care and accurate mortality predictions. To assess if machine learning (ML) could improve predictions, ML algorithms were tested …
View article: HLA<scp>‐G</scp> expression correlates with histological grade but not with prognosis in colorectal carcinoma
HLA<span>‐G</span> expression correlates with histological grade but not with prognosis in colorectal carcinoma Open
Trophoblast‐specific expression of HLA‐G induces immune tolerance for the developing fetus. Pathological HLA‐G expression later in life might contribute to immune escape of various cancers. We studied the still controversial role of HLA‐G …
View article: Point-of-Care Digital Cytology With Artificial Intelligence for Cervical Cancer Screening in a Resource-Limited Setting
Point-of-Care Digital Cytology With Artificial Intelligence for Cervical Cancer Screening in a Resource-Limited Setting Open
In this study, digital microscopy with artificial intelligence was implemented at a rural clinic and used to detect atypical cervical smears with a high sensitivity compared with visual sample analysis.
View article: Machine-learning–driven biomarker discovery for the discrimination between allergic and irritant contact dermatitis
Machine-learning–driven biomarker discovery for the discrimination between allergic and irritant contact dermatitis Open
Significance Contact dermatitis is an inflammatory skin disorder that arises from direct skin contact with irritants or allergens. Representing over 90% of occupational skin disorders, it has a considerable socioeconomic impact, and patien…
View article: Osteoid Metaplasia in Femoral Artery Plaques Is Associated With the Clinical Severity of Lower Extremity Artery Disease in Men
Osteoid Metaplasia in Femoral Artery Plaques Is Associated With the Clinical Severity of Lower Extremity Artery Disease in Men Open
Lamellar metaplastic bone, osteoid metaplasia (OM), is found in atherosclerotic plaques, especially in the femoral arteries. In the carotid arteries, OM has been documented to be associated with plaque stability. This study investigated th…