Johanna M. Colijn
YOU?
Author Swipe
View article: Two Cases of Intraocular Undifferentiated Pleomorphic Sarcoma
Two Cases of Intraocular Undifferentiated Pleomorphic Sarcoma Open
Introduction: Undifferentiated pleomorphic sarcoma (UPS), formerly known as malignant fibrous histiocytoma, is a high-grade soft tissue sarcoma arising from mesenchymal stem cells. UPSs are rare and account for about 5% of all soft tissue …
View article: Systemic Metabolomics in a Framework of Genetics and Lifestyle in Age-Related Macular Degeneration
Systemic Metabolomics in a Framework of Genetics and Lifestyle in Age-Related Macular Degeneration Open
Insights into the pathogenesis of age-related macular degeneration (AMD), a leading cause of blindness, point towards a complex interplay of genetic and lifestyle factors triggering various systemic pathways. This study aimed to characteri…
View article: Enlargement of Geographic Atrophy From First Diagnosis to End of Life
Enlargement of Geographic Atrophy From First Diagnosis to End of Life Open
In this study, enlargement of GA appeared to be highly variable in the general population. More than one-third of incident GA was foveal at first presentation; those with extrafoveal GA developed foveal GA after a mean of 5.6 years. Future…
View article: Performance of Classification Systems for Age-Related Macular Degeneration in the Rotterdam Study
Performance of Classification Systems for Age-Related Macular Degeneration in the Rotterdam Study Open
Findings will help stakeholders select appropriate classification systems for screening, deep learning algorithms, or trials.
View article: Selecting causal risk factors from high-throughput experiments using multivariable Mendelian randomization
Selecting causal risk factors from high-throughput experiments using multivariable Mendelian randomization Open
Modern high-throughput experiments provide a rich resource to investigate causal determinants of disease risk. Mendelian randomization (MR) is the use of genetic variants as instrumental variables to infer the causal effect of a specific r…
View article: Association of Retinal Neurodegeneration on Optical Coherence Tomography With Dementia
Association of Retinal Neurodegeneration on Optical Coherence Tomography With Dementia Open
Thinner RNFL is associated with an increased risk of dementia, including Alzheimer disease, suggesting that retinal neurodegeneration may serve as a preclinical biomarker for dementia.
View article: Thinner retinal layers are associated with changes in the visual pathway: A population‐based study
Thinner retinal layers are associated with changes in the visual pathway: A population‐based study Open
Increasing evidence shows that thinner retinal nerve fiber layer (RNFL) and ganglion cell layer (GCL), assessed on optical coherence tomography (OCT), are reflecting global brain atrophy. Yet, little is known on the relation of these layer…
View article: Five-year progression of unilateral age-related macular degeneration to bilateral involvement: the Three Continent AMD Consortium report
Five-year progression of unilateral age-related macular degeneration to bilateral involvement: the Three Continent AMD Consortium report Open
Purpose To assess the 5-year progression from unilateral to bilateral age-related macular degeneration (AMD) and associated risk factors. Design Pooled data analyses of three prospective population-based cohorts, the Blue Mountains Eye St…