Johanna Maria Catharina Blom
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View article: A Pilot Study on a Reliable and Accessible Approach to Remote Mental Health Assessment: Lessons from Italian Pregnant Women During the COVID-19 Pandemic
A Pilot Study on a Reliable and Accessible Approach to Remote Mental Health Assessment: Lessons from Italian Pregnant Women During the COVID-19 Pandemic Open
Objective: This pilot study assessed the psychological and physical impact of the COVID-19 pandemic on postpartum women that gave birth during the pandemic, and evaluated the feasibility of remote monitoring for maternal mental health. The…
View article: Differences in presynaptic hippocampal GABAergic terminals at the early stage of life in female and male mice: effect of an acute early inflammatory challenge
Differences in presynaptic hippocampal GABAergic terminals at the early stage of life in female and male mice: effect of an acute early inflammatory challenge Open
GABA dictates the efficiency of synaptic connection, influencing its developmental complexity, but its role is tuned by developmental sex differences which affect the efficiency of its innervation. We investigated the efficiency of mechani…
View article: Medicinal Plants for Child Mental Health: Clinical Insights, Active Compounds, and Perspectives for Rational Use
Medicinal Plants for Child Mental Health: Clinical Insights, Active Compounds, and Perspectives for Rational Use Open
Background/Objectives: Anxiety, agitation, and mood disturbances are increasingly common among children and adolescents. Given the limitations of conventional pharmacological treatments in the pediatric population, particularly for subthre…
View article: Cooking for disability: a pilot study on nutritional interventions for mental health support in adults with autism spectrum disorder
Cooking for disability: a pilot study on nutritional interventions for mental health support in adults with autism spectrum disorder Open
Background Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition often accompanied by chronic inflammation and metabolic dysfunction, which are increasingly recognized as key contributors to symptom severity and behavior…
View article: Effects of neonicotinoid and diamide-contaminated agricultural runoff on Lymnaea stagnalis: Insights into stress, neurotoxicity, and antioxidant response
Effects of neonicotinoid and diamide-contaminated agricultural runoff on Lymnaea stagnalis: Insights into stress, neurotoxicity, and antioxidant response Open
Freshwater pollution from agrochemicals poses an increasing threat to aquatic ecosystems. Yet, the sublethal effects of such contaminants on cognition and neural function in non-target invertebrate species remain poorly understood. Using a…
View article: Intrastrain variability in memory formation of freshly collected Lymnaea stagnalis: The influence of stressor type on memory
Intrastrain variability in memory formation of freshly collected Lymnaea stagnalis: The influence of stressor type on memory Open
Understanding how environmental stressors influence memory formation is essential for evaluating the ecological and toxicological impacts of pollution on animal behavior. Using Lymnaea stagnalis snails collected from a pollutant-exposed fr…
View article: Effects of the inhibition of miRNA biogenesis in the central ring ganglia of a widely used invertebrate model species, Lymnaea stagnalis
Effects of the inhibition of miRNA biogenesis in the central ring ganglia of a widely used invertebrate model species, Lymnaea stagnalis Open
View article: Building trust in clinical research: a systems approach to ethical engagement and sustainable outcomes
Building trust in clinical research: a systems approach to ethical engagement and sustainable outcomes Open
Trust and trustworthiness are critical to the success of clinical research, profoundly influencing participant engagement, data integrity, and study outcomes. These behaviors emerge from complex, dynamic interactions within the clinical re…
View article: Investigating the Multidimensional Structure of Apathy in Cognitive Decline: An Exploratory Network Analysis of the Apathy Evaluation Scale
Investigating the Multidimensional Structure of Apathy in Cognitive Decline: An Exploratory Network Analysis of the Apathy Evaluation Scale Open
View article: Evaluating Sleep in Pediatric Cancer: A Scoping Review of Assessment Tools for Quality and Care
Evaluating Sleep in Pediatric Cancer: A Scoping Review of Assessment Tools for Quality and Care Open
Background Pediatric cancer patients experience unique and multifaceted sleep disturbances due to the disease, treatment regimens, and the hospital environment. These disruptions can detrimentally impact neurocognitive functioning, emotion…
View article: Mapping the trajectory of psychotic symptoms and their interaction with antipsychotic treatment: a longitudinal network intervention study
Mapping the trajectory of psychotic symptoms and their interaction with antipsychotic treatment: a longitudinal network intervention study Open
Antipsychotic efficacy in schizophrenia spectrum disorders (SSD) is commonly evaluated using static measures that fail to capture the dynamic evolution of symptoms and the unfolding impact of treatment over time. Network Intervention Analy…
View article: First evidence of an anxiety-like behavior and its pharmacological modulation in a molluscan model organism, Lymnaea stagnalis
First evidence of an anxiety-like behavior and its pharmacological modulation in a molluscan model organism, Lymnaea stagnalis Open
View article: Unraveling lipopolysaccharide-induced behavioral and molecular effects in Lymnaea stagnalis, an emerging model organism for translational neuroscience
Unraveling lipopolysaccharide-induced behavioral and molecular effects in Lymnaea stagnalis, an emerging model organism for translational neuroscience Open
View article: An exploratory network analysis to investigate schizotypy’s structure using the ‘Multidimensional Schizotypy Scale’ and ‘Oxford-Liverpool Inventory’ in a healthy cohort
An exploratory network analysis to investigate schizotypy’s structure using the ‘Multidimensional Schizotypy Scale’ and ‘Oxford-Liverpool Inventory’ in a healthy cohort Open
View article: Exploring apathy components and their relationship in cognitive decline: insights from a network cross-sectional study
Exploring apathy components and their relationship in cognitive decline: insights from a network cross-sectional study Open
View article: Carnosine modulates Aβ-induced transcriptional aberrations in murine microglial cells
Carnosine modulates Aβ-induced transcriptional aberrations in murine microglial cells Open
View article: Advanced AI techniques for classifying Alzheimer’s disease and mild cognitive impairment
Advanced AI techniques for classifying Alzheimer’s disease and mild cognitive impairment Open
Background Alzheimer’s disease and mild cognitive impairment are often difficult to differentiate due to their progressive nature and overlapping symptoms. The lack of reliable biomarkers further complicates early diagnosis. As the global …
View article: Exploring Sex-Based Neuropsychological Outcomes in Pediatric Brain Cancer Survivors: A Pilot Study
Exploring Sex-Based Neuropsychological Outcomes in Pediatric Brain Cancer Survivors: A Pilot Study Open
Background: The increasing survival rates among pediatric cancer patients underscore the critical need to understand the long-term psychosocial impacts of cancer treatments, such as cisplatin and carboplatin. While these treatments are lif…
View article: Hot and cold exposure triggers distinct transcriptional and behavioral responses in laboratory-inbred pond snails
Hot and cold exposure triggers distinct transcriptional and behavioral responses in laboratory-inbred pond snails Open
View article: Quercetin, the new stress buster: Investigating the transcriptional and behavioral effects of this flavonoid on multiple stressors using Lymnaea stagnalis
Quercetin, the new stress buster: Investigating the transcriptional and behavioral effects of this flavonoid on multiple stressors using Lymnaea stagnalis Open
View article: Behavioral and transcriptional effects of carnosine in the central ring ganglia of the pond snail <i>Lymnaea stagnalis</i>
Behavioral and transcriptional effects of carnosine in the central ring ganglia of the pond snail <i>Lymnaea stagnalis</i> Open
Carnosine is a naturally occurring endogenous dipeptide with well‐recognized anti‐inflammatory, antioxidant, and neuroprotective effects at the central nervous system level. To date, very few studies have been focused on the ability of car…
View article: Ethical framework for FACILITATE: a foundation for the return of clinical trial data to participants
Ethical framework for FACILITATE: a foundation for the return of clinical trial data to participants Open
This paper discusses the importance of return of clinical trial data to patients in the context of the FACILITATE project that aims to develop a participant-centric approach for the systematic return of individual clinical trial data. It r…
View article: Time- and Region-specific Effect of Vortioxetine on Central LPS-induced Transcriptional Regulation of NLRP3 Inflammasome
Time- and Region-specific Effect of Vortioxetine on Central LPS-induced Transcriptional Regulation of NLRP3 Inflammasome Open
Background: Inflammasome overactivation, multiprotein complexes that trigger inflammatory responses, plays a critical role in Major Depressive Disorder (MDD) pathogenesis and treatment responses. Indeed, different antidepressants alleviate…
View article: Investigating the structure of Schizotypy through the “Multidimensional Schizotypy Scale” and “Oxford-Liverpool Inventory”: an Exploratory network analysis approach in the healthy population
Investigating the structure of Schizotypy through the “Multidimensional Schizotypy Scale” and “Oxford-Liverpool Inventory”: an Exploratory network analysis approach in the healthy population Open
Background Schizophrenia spectrum disorders and schizotypy share traits across positive, negative, and disorganized domains. Instruments like MSS and O-LIFE provide insights into these dimensions. Despite challenges posed by cultural varia…
View article: Different stressors uniquely affect the expression of endocannabinoid‐metabolizing enzymes in the central ring ganglia of <i>Lymnaea stagnalis</i>
Different stressors uniquely affect the expression of endocannabinoid‐metabolizing enzymes in the central ring ganglia of <i>Lymnaea stagnalis</i> Open
The endocannabinoid system (ECS) plays an important role in neuroprotection, neuroplasticity, energy balance, modulation of stress, and inflammatory responses, acting as a critical link between the brain and the body's peripheral regions, …
View article: The Impact of Music Therapy in a Pediatric Oncology Setting: An Italian Observational Network Study
The Impact of Music Therapy in a Pediatric Oncology Setting: An Italian Observational Network Study Open
Background: Music Therapy (MT) is a non-pharmacological, art-based intervention that employs music experiences within a therapeutic alliance to attend to clients’ physical, emotional, cognitive, and social requirements. This is the first s…
View article: A translational and multidisciplinary approach to studying the Garcia effect, a higher form of learning with deep evolutionary roots
A translational and multidisciplinary approach to studying the Garcia effect, a higher form of learning with deep evolutionary roots Open
Animals, including humans, learn and remember to avoid a novel food when its ingestion is followed, hours later, by sickness – a phenomenon initially identified during World War II as a potential means of pest control. In the 1960s, John G…
View article: Low TGF-β1 plasma levels are associated with cognitive decline in Down syndrome
Low TGF-β1 plasma levels are associated with cognitive decline in Down syndrome Open
Almost all individuals with Down’s syndrome (DS) show the characteristic neuropathological features of Alzheimer’s disease (AD) by the age of 40, yet not every individual with DS experiences symptoms of AD later in life. Similar to neuroty…
View article: A19 THE IMPACT OF FOOD INSECURITY ON ADHERENCE TO A GLUTEN-FREE DIET IN THE ADULT CELIAC DISEASE POPULATION ATTENDING A DEDICATED CELIAC CLINIC
A19 THE IMPACT OF FOOD INSECURITY ON ADHERENCE TO A GLUTEN-FREE DIET IN THE ADULT CELIAC DISEASE POPULATION ATTENDING A DEDICATED CELIAC CLINIC Open
Background A strict gluten-free diet (GFD) is currently the only treatment for celiac disease (CeD), but a GFD can be inconvenient and expensive. CeD patients who are food insecure (FI) face threats to GFD adherence, overall health, and qu…
View article: The network intervention analysis to map the interplay of symptoms and drug treatment in major depressive disorder
The network intervention analysis to map the interplay of symptoms and drug treatment in major depressive disorder Open