Johanna Rohrhofer
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View article: The Clinical Relevance of Mast Cell Activation in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
The Clinical Relevance of Mast Cell Activation in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Open
Background/Objectives: Growing evidence suggests that mast cell activation (MCA) may contribute to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), a debilitating disorder characterized by persistent fatigue and post-exertional…
View article: Species-specific N-glycan patterns in animal and human breast milk samples
Species-specific N-glycan patterns in animal and human breast milk samples Open
The main components of milk are protein, fat and carbohydrates. Glycans are complex carbohydrate structures covalently bound to proteins and lipids or exist freely in solutions. The function of glycans in nature is to contribute to structu…
View article: Gastrointestinal Barrier Disruption in Post‐<scp>COVID</scp> Syndrome Fatigue Patients
Gastrointestinal Barrier Disruption in Post‐<span>COVID</span> Syndrome Fatigue Patients Open
Background Post‐COVID Syndrome (PCS) is the term for a condition with persistent symptoms in a proportion of COVID‐19 patients after asymptomatic, mild, or severe disease courses. Numbers vary, but the current estimate is that after COVID‐…
View article: Immunological Patient Stratification in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Immunological Patient Stratification in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Open
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex disease characterized by profound fatigue, post-exertional malaise (PEM), and neurocognitive dysfunction. Immune dysregulation and gastrointestinal symptoms are commo…
View article: Immunological Patient Stratification in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Immunological Patient Stratification in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Open
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex disease characterized by profound fatigue, post-exertional malaise (PEM), and neurocognitive dysfunction. Immune dysregulation and gastrointestinal symptoms are commo…
View article: Association between <scp>Epstein‐Barr‐Virus</scp> reactivation and development of Long‐<scp>COVID</scp> fatigue
Association between <span>Epstein‐Barr‐Virus</span> reactivation and development of Long‐<span>COVID</span> fatigue Open
To the Editor, Post-viral fatigue after SARS-CoV-2 infection is a major concern in the ongoing COVID-19 pandemic. Up to 10% of patients develop Long-COVID,1 a syndrome defined by the National Institute for Health and Care Excellence as pos…
View article: Real‐life evaluation of molecular multiplex IgE test methods in the diagnosis of pollen associated food allergy
Real‐life evaluation of molecular multiplex IgE test methods in the diagnosis of pollen associated food allergy Open
Background Diagnosis of food allergies is challenging, as combining information from specific IgE (sIgE)‐sensitization pattern and skin prick tests (SPTs) with clinical history is necessary for a personalized management of allergic patient…
View article: DMTMM-mediated methylamidation for MALDI mass spectrometry analysis of N-glycans with structurally conserved sialic acid residues in biological fluids “via direttissima”
DMTMM-mediated methylamidation for MALDI mass spectrometry analysis of N-glycans with structurally conserved sialic acid residues in biological fluids “via direttissima” Open
Characterization of serum glycoprotein N-glycans with matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) in positive-ion mode needs a derivatization step to stabilize and neutralize the negative charge on sialic acids…
View article: Evaluation of Immune Dysregulation in an Austrian Patient Cohort Suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Evaluation of Immune Dysregulation in an Austrian Patient Cohort Suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Open
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a severe multi-systemic disease characterized by debilitating fatigue that is not relieved by rest. The causes of the disease are still largely unexplained, and no causative tr…
View article: The Impact of Dietary Sphingolipids on Intestinal Microbiota and Gastrointestinal Immune Homeostasis
The Impact of Dietary Sphingolipids on Intestinal Microbiota and Gastrointestinal Immune Homeostasis Open
The large surfaces of gastrointestinal (GI) organs are well adapted to their diverse tasks of selective nutritional uptake and defense against the external environment. To maintain a functional balance, a vast number of immune cells is loc…
View article: Gastric Enzyme Supplementation Inhibits Food Allergy in a BALB/c Mouse Model
Gastric Enzyme Supplementation Inhibits Food Allergy in a BALB/c Mouse Model Open
Impaired gastric digestion due to suppressed gastric acidity enhances the risk for food allergy development. In the current study, we aimed to evaluate the impact of a supported gastric digestion via application of a pharmaceutical gastric…
View article: Immune Effects of the Nitrated Food Allergen Beta-Lactoglobulin in an Experimental Food Allergy Model
Immune Effects of the Nitrated Food Allergen Beta-Lactoglobulin in an Experimental Food Allergy Model Open
Food proteins may get nitrated by various exogenous or endogenous mechanisms. As individuals might get recurrently exposed to nitrated proteins via daily diet, we aimed to investigate the effect of repeatedly ingested nitrated food protein…