Johannes Jungilligens
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View article: Effectiveness and implementation of an inpatient mental health care pathway at an epilepsy center: A prospective service evaluation
Effectiveness and implementation of an inpatient mental health care pathway at an epilepsy center: A prospective service evaluation Open
Objectives This hybrid study assessed the implementation and clinical effectiveness of a structured mental health care workflow for epilepsy. Methods Eligible inpatients were screened systematically. Patients with scores above cutoff score…
View article: Functional Neurological Disorder Among Neurology In‐Patients
Functional Neurological Disorder Among Neurology In‐Patients Open
Background The high prevalence of functional neurological disorders (FND) in specialized neurological services such as epilepsy centers or dizziness clinics is well established. Few studies exist that investigate the frequency of FND among…
View article: Changes in brain network dynamics during functional/dissociative seizures: An exploratory pilot study on EEG microstates
Changes in brain network dynamics during functional/dissociative seizures: An exploratory pilot study on EEG microstates Open
The pathophysiology of functional/dissociative seizures (FDS), also known as psychogenic nonepileptic seizures, remains incompletely understood. Current theories suggest that ictal changes in self-awareness and behavioural control are like…
View article: The role of the precuneus in dissociative seizures: A structural neuroimaging study
The role of the precuneus in dissociative seizures: A structural neuroimaging study Open
The neurobiology and neuropsychology of dissociative seizures is increasingly well understood, but a gap remains in understanding the neurobiological underpinnings of one of its core features: dissociation. As a transdiagnostic phenomenon,…
View article: Locus coeruleus co‐activation patterns at rest show higher state persistence in patients with dissociative seizures: A Pilot Study
Locus coeruleus co‐activation patterns at rest show higher state persistence in patients with dissociative seizures: A Pilot Study Open
Objective Dissociative seizures are paroxysmal disruptions of awareness and behavioral control in the context of affective arousal. Alterations in stress‐related endocrine function have been demonstrated, but the timescale of dissociation …
View article: Neurocognitive performance in functional neurological disorder: A systematic review and meta‐analysis
Neurocognitive performance in functional neurological disorder: A systematic review and meta‐analysis Open
Background and purpose Cognitive complaints are common in functional neurological disorder (FND), but it is unclear whether objective neurocognitive deficits are present. This systematic review summarized validated/standardized cognitive t…
View article: The effect of live music therapy on white matter microstructure in very preterm infants – A randomized controlled trial
The effect of live music therapy on white matter microstructure in very preterm infants – A randomized controlled trial Open
Clinical trial number DRKS00025753.
View article: Aktuelle Forschungsergebnisse zur Neuropsychologie dissoziativer Anfälle
Aktuelle Forschungsergebnisse zur Neuropsychologie dissoziativer Anfälle Open
Zusammenfassung Dissoziative Anfälle sind komplexe und oftmals nicht ausreichend verstandene Symptome an der Grenze von körperlichen zu psychischen Phänomenen. Dies ist sowohl im Kinder- und Jugend- als auch im Erwachsenenbereich ein Probl…
View article: Locus coeruleus co-activation patterns at rest show higher state persistence in patients with dissociative seizures: A pilot study
Locus coeruleus co-activation patterns at rest show higher state persistence in patients with dissociative seizures: A pilot study Open
Objective. Dissociative seizures are paroxysmal disruptions of awareness and behavioural control in the context of affective arousal. Alterations in stress-related endocrine function have been demonstrated, but the timescale of dissociatio…
View article: Heartbeat evoked potentials and autonomic arousal during dissociative seizures: insights from electrophysiology and neuroimaging
Heartbeat evoked potentials and autonomic arousal during dissociative seizures: insights from electrophysiology and neuroimaging Open
Introduction Dissociative seizures often occur in the context of dysregulated affective arousal and entail dissociative symptoms such as a disintegration of bodily awareness. However, the interplay between affective arousal and changes in …
View article: Healthcare for sex workers—access, barriers, and needs
Healthcare for sex workers—access, barriers, and needs Open
Background Stigma has a significant impact on the health of different societal groups and contributes to inequalities in healthcare. Sex work is associated with significant social stigma, which has detrimental effects on sex workers’ acces…
View article: Cognitive performance in functional neurological disorder: A systematic review and meta-analysis
Cognitive performance in functional neurological disorder: A systematic review and meta-analysis Open
Background: Cognitive complaints are common in functional neurological disorder (FND), but it is unclear whether objective neurocognitive deficits are present. This systematic review summarised validated/standardised cognitive test perform…
View article: Response to the Letter Concerning the Publication: Neuroimaging in Functional Neurological Disorder: State of the Field and Research Agenda. Perez DL et al. Neuroimage Clin. 2021;30:102623
Response to the Letter Concerning the Publication: Neuroimaging in Functional Neurological Disorder: State of the Field and Research Agenda. Perez DL et al. Neuroimage Clin. 2021;30:102623 Open
View article: Heartbeat evoked potentials and autonomic arousal during dissociative seizures
Heartbeat evoked potentials and autonomic arousal during dissociative seizures Open
Dissociative seizures often occur in the context of dysregulated affective arousal and entail dissociative symptoms such as a disintegration of bodily awareness. However, the interplay between affective arousal and changes in interoceptive…
View article: Testfile
Testfile Open
This is a testfile for a preprint
View article: Dissociative seizures in the emergency room: room for improvement
Dissociative seizures in the emergency room: room for improvement Open
Background Dissociative seizures, also known as functional or psychogenic non-epileptic seizures, account for 11%–27% of all emergency seizure presentations. Misdiagnosis as epileptic seizures is common and leads to ineffective and potenti…
View article: Linking gene expression patterns and brain morphometry to trauma and symptom severity in patients with functional seizures
Linking gene expression patterns and brain morphometry to trauma and symptom severity in patients with functional seizures Open
View article: Specific relations of visual skills and executive functions in elite soccer players
Specific relations of visual skills and executive functions in elite soccer players Open
Visual and cognitive skills are key to successful functioning in highly demanding settings such as elite sports. However, their mutual influence and interdependencies are not sufficiently understood yet. This cross-sectional study examined…
View article: A new science of emotion: implications for functional neurological disorder
A new science of emotion: implications for functional neurological disorder Open
Functional neurological disorder reflects impairments in brain networks leading to distressing motor, sensory and/or cognitive symptoms that demonstrate positive clinical signs on examination incongruent with other conditions. A central is…
View article: Point-of-Care Testing Using a Neuropsychology Pocketcard Set: A Preliminary Validation Study
Point-of-Care Testing Using a Neuropsychology Pocketcard Set: A Preliminary Validation Study Open
Neurocognitive screening instruments usually require printed sheets and additional accessories, and can be unsuitable for low-threshold use during ward rounds or emergency workup, especially in patients with motor impairments. Here, we tes…
View article: Cortical thickness in default mode network hubs correlates with clinical features of dissociative seizures
Cortical thickness in default mode network hubs correlates with clinical features of dissociative seizures Open
View article: Linking gene expression patterns and brain morphometry to trauma and symptom severity in patients with functional seizures
Linking gene expression patterns and brain morphometry to trauma and symptom severity in patients with functional seizures Open
Objective Adverse life experiences (ALEs) increase the susceptibility to functional (somatoform/dissociative) symptoms, likely through neurodevelopmental effects. This analysis aimed to illuminate potential genetic influences in neuroanato…
View article: Misdiagnosis of prolonged psychogenic non-epileptic seizures as status epilepticus: epidemiology and associated risks
Misdiagnosis of prolonged psychogenic non-epileptic seizures as status epilepticus: epidemiology and associated risks Open
Objective To determine the epidemiology of prolonged psychogenic non-epileptic seizures (pPNES) misdiagnosed as status epilepticus, as well as the risks associated with non-indicated treatment. Methods We performed an individual patient da…
View article: Diagnostic challenges in patients with temporal lobe seizures and features of autoimmune limbic encephalitis
Diagnostic challenges in patients with temporal lobe seizures and features of autoimmune limbic encephalitis Open
Background and purpose Consensus criteria for autoimmune limbic encephalitis (ALE) allow for a diagnosis even without neuronal antibodies (Abs), but it remains unclear which clinical features should prompt neuronal Ab screening in temporal…
View article: Neuroimaging in Functional Neurological Disorder: State of the Field and Research Agenda
Neuroimaging in Functional Neurological Disorder: State of the Field and Research Agenda Open
View article: Microstructural integrity of affective neurocircuitry in patients with dissociative seizures is associated with emotional task performance, illness severity and trauma history
Microstructural integrity of affective neurocircuitry in patients with dissociative seizures is associated with emotional task performance, illness severity and trauma history Open
View article: Suggestive seizure induction for inpatients with suspected psychogenic nonepileptic seizures
Suggestive seizure induction for inpatients with suspected psychogenic nonepileptic seizures Open
Objective To determine the utility of suggestive seizure induction for inpatient work‐up of suspected psychogenic nonepileptic seizures (PNES). Methods Prospective study of epilepsy center inpatient admissions with suspected PNES. Patients…