John A. Baroch
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Molecular Characterization of Non-H5 and Non-H7 Avian Influenza Viruses from Non-Mallard Migratory Waterbirds of the North American Flyways, 2006–2011 Open
The surveillance of migratory waterbirds (MWs) for avian influenza virus (AIV) is indispensable for the early detection of a potential AIV incursion into poultry. Surveying AIV infections and virus subtypes in understudied MW species could…
Nanopore sequencing as a rapid tool for identification and pathotyping of avian influenza A viruses Open
We report whole-genome sequencing of influenza A virus (IAV) with 100% diagnostic sensitivity and results available in 500× coverage from each of 16 reference virus isolates evaluated. Subgenomic viral sequences obtained in 3 cases using S…
Tissue tropisms opt for transmissible reassortants during avian and swine influenza A virus co-infection in swine Open
Genetic reassortment between influenza A viruses (IAVs) facilitate emergence of pandemic strains, and swine are proposed as a "mixing vessel" for generating reassortants of avian and mammalian IAVs that could be of risk to mammals, includi…
Influenza D Virus Infection in Feral Swine Populations, United States Open
Influenza D virus (IDV) has been identified in domestic cattle, swine, camelid, and small ruminant populations across North America, Europe, Asia, South America, and Africa. Our study investigated seroprevalence and transmissibility of IDV…
Feral Swine in the United States Have Been Exposed to both Avian and Swine Influenza A Viruses Open
Influenza A viruses (IAVs) in swine can cause sporadic infections and pandemic outbreaks among humans, but how avian IAV emerges in swine is still unclear. Unlike domestic swine, feral swine are free ranging and have many opportunities for…
Limited Antigenic Diversity in Contemporary H7 Avian-Origin Influenza A Viruses from North America Open
Subtype H7 avian–origin influenza A viruses (AIVs) have caused at least 500 confirmed human infections since 2003 and culling of >75 million birds in recent years. Here we antigenically and genetically characterized 93 AIV isolates from No…
Antigenic Characterization of H3 Subtypes of Avian Influenza A Viruses from North America Open
Besides humans, H3 subtypes of influenza A viruses (IAVs) can infect various animal hosts, including avian, swine, equine, canine, and sea mammal species. These H3 viruses are both antigenically and genetically diverse. Here, we characteri…
A quantitative RT-PCR assay for rapid detection of EurasianlineageH10 subtype influenza A virus Open
Influenza A viruses (IAVs) are single-stranded, negative sense RNA viruses. IAV subtype is determined on the basis of the viral surface glycoproteins, hemagglutinin (HA), and neuraminidase (NA). To date, 18 HA and 11 NA subtypes have been …