John A. Persing
YOU?
Author Swipe
View article: AXIN1 mutations in nonsyndromic craniosynostosis
AXIN1 mutations in nonsyndromic craniosynostosis Open
OBJECTIVE Occurring once in every 2000 live births, craniosynostosis (CS) is the most frequent cranial birth defect. Although the genetic etiologies of syndromic CS cases are well defined, the genetic cause of most nonsyndromic cases remai…
View article: D125. A Diffusion Tensor Imaging Comparison of White Matter Development in Nonsyndromic Craniosynostosis to Neurotypical Infants
D125. A Diffusion Tensor Imaging Comparison of White Matter Development in Nonsyndromic Craniosynostosis to Neurotypical Infants Open
PURPOSE: Nonsyndromic craniosynostosis (NSC) is associated with neurocognitive deficits, and intervention at infancy is standard of care to limit the negative effects of NSC on brain development. In this study, diffusion tensor imaging (DT…
View article: Quantifying Facial Feminization Surgery’s Impact: Focus on Patient Facial Satisfaction
Quantifying Facial Feminization Surgery’s Impact: Focus on Patient Facial Satisfaction Open
Background: Facial feminization surgery (FFS) has been associated with improving gender dysphoria in transgender patients. This study aimed to quantify the impact of surgery on patient facial satisfaction, using the FACE-Q and a quality-of…
View article: Comparison of Emotional and Behavioral Regulation Between Metopic and Sagittal Synostosis
Comparison of Emotional and Behavioral Regulation Between Metopic and Sagittal Synostosis Open
Purpose Children with surgically corrected nonsyndromic craniosynostosis have been previously found to have neurocognitive and behavioral difficulties. Children with metopic synostosis have been described to have more difficulties than chi…
View article: Generative Pre-Trained Transformers (GPT) Artificial intelligence – Assessing the Accuracy of ChatGPT as an Adjunct for Peri-operative Care
Generative Pre-Trained Transformers (GPT) Artificial intelligence – Assessing the Accuracy of ChatGPT as an Adjunct for Peri-operative Care Open
PURPOSE: As artificial intelligence (AI) innovation blossoms, minimal advancements have occurred in its integration within plastic surgery; this is especially disadvantageous given AI's potential for improved patient outcomes and experienc…
View article: FACE-Q Satisfaction Ratings Are Higher After Facial Feminization Surgery Than Hormone Replacement Therapy Alone
FACE-Q Satisfaction Ratings Are Higher After Facial Feminization Surgery Than Hormone Replacement Therapy Alone Open
FFS is associated with greater satisfaction with overall facial appearance, especially compared to transgender patients only on HRT. Insurance was the greatest barrier to receiving FFS. Improved access to surgery is needed to yield higher …
View article: 26. The Association of Age at Surgery and Behavioral Functioning in Children with Surgically Corrected Metopic Craniosynostosis
26. The Association of Age at Surgery and Behavioral Functioning in Children with Surgically Corrected Metopic Craniosynostosis Open
PURPOSE: Nonsyndromic craniosynostosis is associated with neurocognitive and behavioral deficits. We examined the association of age at surgery and long-term behavioral functioning at school age in children with surgically-corrected metopi…
View article: 1. Mutations in FOXI3 Cause Microtia and Craniofacial Microsomia
1. Mutations in FOXI3 Cause Microtia and Craniofacial Microsomia Open
PURPOSE: Craniofacial microsomia (CFM) represents a spectrum of craniofacial malformation, ranging from isolated microtia with or without aural atresia to underdevelopment of the mandible, maxilla, orbit, facial soft tissue, and/or facial …
View article: 41. AI Radiographic Severity Assessment and Age at Surgery Associated with Neurocognitive Outcomes in Metopic Craniosynostosis
41. AI Radiographic Severity Assessment and Age at Surgery Associated with Neurocognitive Outcomes in Metopic Craniosynostosis Open
PURPOSE: Radiographic severity of metopic synostosis has been suggested as a possible predictor of neurocognitive outcomes. Recently, artificial intelligence (AI) has been used to quantify severity. Age at surgery has been shown to predict…
View article: PC16. Mutations in FOXI3 Cause Microtia and Craniofacial Microsomia
PC16. Mutations in FOXI3 Cause Microtia and Craniofacial Microsomia Open
PURPOSE: Craniofacial microsomia (CFM) represents a spectrum of craniofacial malformation, ranging from isolated microtia to underdevelopment of the mandible, maxilla, orbit, facial soft tissue, and/or facial nerve. The genetic causes of C…
View article: Reimbursement Rates among Surgeons for Facial Trauma Call
Reimbursement Rates among Surgeons for Facial Trauma Call Open
BACKGROUND: Facial trauma accounts for over 3 million emergency room encounters each year. Currently there is no specific data regarding reimbursement rates, scope of practice, or hospital requirements when it comes to facial trauma call. …
View article: Presence of Cosmetic and Aesthetic Surgery on TikTok
Presence of Cosmetic and Aesthetic Surgery on TikTok Open
In the past decade, social media has had an important role in shaping the public perception of health care. Social media offers an avenue for health care education and for physicians to promote their practice. Despite its rising popularity…
View article: Impact of the Step 1 Scoring Change on the Upcoming Application Cycle
Impact of the Step 1 Scoring Change on the Upcoming Application Cycle Open
The recent transition of United States Medical Licensing Examination Step 1 to a pass–fail system was intended to promote student wellness. However, some have raised concerns for increased emphasis on subjective measures of performance.1 A…
View article: IQ Assessment in Craniofacial Neurocognitive Studies: Interpreting Results Relative to Evidence-based Systematic Analysis
IQ Assessment in Craniofacial Neurocognitive Studies: Interpreting Results Relative to Evidence-based Systematic Analysis Open
Recent studies have evaluated the relationship of timing of surgery, type of surgery, and genetic factors with long-term cognitive function in craniosynostosis.1,2 Intelligence quotient (IQ), which is standardized to a mean score of 100 an…
View article: 130. De Novo Mutations in 555 Trios Implicate Chromatin Modification, Transcriptional Regulation, and Retinoic Acid Signaling in Syndromic Craniosynostosis
130. De Novo Mutations in 555 Trios Implicate Chromatin Modification, Transcriptional Regulation, and Retinoic Acid Signaling in Syndromic Craniosynostosis Open
Purpose: Craniosynostosis (CS) is the most common congenital cranial anomaly. Several Mendelian forms of syndromic CS are well-described, but the genetic etiology of a substantial fraction of cases remains undefined. Methods: We analyzed e…
View article: QS48. Impact of Insurance Status on Treatment Outcomes and Compliance in Orthotic Helmet Therapy for Plagiocephaly
QS48. Impact of Insurance Status on Treatment Outcomes and Compliance in Orthotic Helmet Therapy for Plagiocephaly Open
Impact of Insurance Status on Treatment Outcomes and Compliance in Orthotic Helmet Therapy for Plagiocephaly Purpose: Deformational Plagiocephaly (DP) is a condition in which an infant's skull is misshapen due to uneven external pressure. …
View article: 28. NATIONAL DISPARITIES IN MEDICAID ACCESS TO ORTHOTIC HELMET THERAPY FOR DEFORMATIONAL PLAGIOCEPHALY
28. NATIONAL DISPARITIES IN MEDICAID ACCESS TO ORTHOTIC HELMET THERAPY FOR DEFORMATIONAL PLAGIOCEPHALY Open
PURPOSE: Cranial orthosis, or helmet therapy, is used for the treatment of deformational plagiocephaly (DP). Factors affecting outcomes of therapy have been examined, but the role of insurance provider is understudied. We analyzed referral…
View article: 26. NEUROCOGNITIVE OUTCOMES IN POSTOPERATIVE CRANIOSYNOSTOSIS PATIENTS
26. NEUROCOGNITIVE OUTCOMES IN POSTOPERATIVE CRANIOSYNOSTOSIS PATIENTS Open
PURPOSE: Craniosynostosis has been associated with a variety of neurocognitive deficits. This is the largest cohort of postoperative craniosynostosis patients to undergo formal neurocognitive testing at school age. METHODS: Patients diagno…
View article: Abstracts from the American Society of Pediatric Neurosurgeons Virtual Meeting
Abstracts from the American Society of Pediatric Neurosurgeons Virtual Meeting Open
Background/Purpose: Next generation sequencing technologies have permitted a molecular understanding of the patho-etiology of non-syndromic craniosynostosis (NSC), however the underpinnings of the subtle neurocognitive deficits observed in…
View article: Does Different Cranial Suture Synostosis Influence Orbit Volume and Morphology in Apert Syndrome?
Does Different Cranial Suture Synostosis Influence Orbit Volume and Morphology in Apert Syndrome? Open
BACKGROUND: This study compared the orbital and periorbital morphological variations in Apert syndrome patients who have different cranial vault suture synostosis, so as to provide an anatomic basis for individualized surgical planning. ME…
View article: Long-term Follow-up of Preoperative Infant Event-related Potentials in School-age Children with Craniosynostosis
Long-term Follow-up of Preoperative Infant Event-related Potentials in School-age Children with Craniosynostosis Open
Background: Previous studies demonstrated impaired auditory processing in children with sagittal and metopic craniosynostosis before surgical correction. This study investigated whether worse presurgical neural response as assessed by even…
View article: Cerebral cortex maldevelopment in syndromic craniosynostosis
Cerebral cortex maldevelopment in syndromic craniosynostosis Open
Aim To assess the relationship of surface area of the cerebral cortex to intracranial volume (ICV) in syndromic craniosynostosis. Method Records of 140 patients (64 males, 76 females; mean age 8y 6mo [SD 5y 6mo], range 1y 2mo–24y 2mo) with…
View article: 5: Long-term Follow-up of Pre-operative Infant Event-related Potential in Children with Craniosynostosis
5: Long-term Follow-up of Pre-operative Infant Event-related Potential in Children with Craniosynostosis Open
Purpose: Event-related potentials (ERPs) provide a real-time safe, noninvasive method to assess neural networks in infancy. Limited data exist, however, as to the predictive value of these results with eventual neurocognitive outcomes at s…
View article: QS3: Influence Of Nonsyndromic Bicoronal Synostosis And Syndromic Influences On And Periorbital Malformation
QS3: Influence Of Nonsyndromic Bicoronal Synostosis And Syndromic Influences On And Periorbital Malformation Open
Background Oculo-orbital disproportion in patients with craniosynostosis have similarities and dissimilarities between syndromic and nonsyndromic cases. We hypothesize these two conditions have specific individual influences as it relates …
View article: QS1: Nasopharyngeal Airway and Subcranial Space Analysis in Pfeiffer Syndrome
QS1: Nasopharyngeal Airway and Subcranial Space Analysis in Pfeiffer Syndrome Open
Background: Tracheotomy in infancy helps patients with Pfeiffer syndrome survive by preventing respiratory crisis, however, difficulty in decannulation consequently may be a challenge. This study attempts to investigate the regional abnorm…
View article: Virtual Coordinate System in Unicoronal Synostosis
Virtual Coordinate System in Unicoronal Synostosis Open
Background: We propose a landmark-based, virtual coordinate system, specifically designed for assessment of asymmetrical craniofacial anatomy associated with unicoronal synostosis. Method: CT scans of 33 patients with nonsyndromic unicoron…
View article: A comparison of perioperative safety for breast augmentation in cis- vs. trans patients
A comparison of perioperative safety for breast augmentation in cis- vs. trans patients Open
Top surgery improves quality of life in transgender women. Despite the more complex pre-operative risk profile in the transgender population, there is no difference in peri-operative safety profiles. Plastic surgeons treating this patient …