John Berger
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View article: Impact of Fetal Diagnosis on the Management of Right Superior Vena Cava to Left Atrium
Impact of Fetal Diagnosis on the Management of Right Superior Vena Cava to Left Atrium Open
Prenatal diagnosis of cardiac defects can significantly aid postnatal care. We present 2 cases of a rare anomaly of the right superior vena cava draining into the left atrium, one postnatally diagnosed and one prenatally diagnosed, to high…
View article: Interventional Strategies for Children with Progressive Pulmonary Hypertension Despite Optimal Therapy: An Official American Thoracic Society Clinical Practice Guideline
Interventional Strategies for Children with Progressive Pulmonary Hypertension Despite Optimal Therapy: An Official American Thoracic Society Clinical Practice Guideline Open
Background: Pulmonary hypertension in children is progressive with wide variability in prognosis. This document provides an evidence-based clinical practice guideline for the management of children with progressive pulmonary hypertension d…
View article: Longitudinal Assessment of T1 Mapping Trends Disease in Pediatric Patients With Heart Transplant
Longitudinal Assessment of T1 Mapping Trends Disease in Pediatric Patients With Heart Transplant Open
Background Surveillance for heart transplant rejection by endomyocardial biopsy is invasive and may yield false negatives. T1 and T2 mapping from cardiac magnetic resonance can demonstrate elevations with rejection. We sought to evaluate l…
View article: Resuscitation arterial waveform quantification and outcomes in pediatric bidirectional Glenn and Fontan patients
Resuscitation arterial waveform quantification and outcomes in pediatric bidirectional Glenn and Fontan patients Open
Background Resuscitation with chest compressions and positive pressure ventilation in Bidirectional Glenn (BDG) or Fontan physiology may compromise passive venous return and accentuate neurologic injury. We hypothesized that arterial press…
View article: Long-term outcome of children with newly diagnosed pulmonary arterial hypertension: results from the global TOPP registry
Long-term outcome of children with newly diagnosed pulmonary arterial hypertension: results from the global TOPP registry Open
Background and aims The Tracking Outcomes and Practice in Pediatric Pulmonary Hypertension (TOPP) registry is a global network established to gain insights into the disease course and long-term outcomes of paediatric pulmonary arterial hyp…
View article: Characterization of Inhaled Nitric Oxide Use for Cardiac Indications in Pediatric Patients*
Characterization of Inhaled Nitric Oxide Use for Cardiac Indications in Pediatric Patients* Open
OBJECTIVES: Characterize the use of inhaled nitric oxide (iNO) for pediatric cardiac patients and assess the relationship between patient characteristics before iNO initiation and outcomes following cardiac surgery. DESIGN: Observational c…
View article: Native T1 mapping detects both acute clinical rejection and graft dysfunction in pediatric heart transplant patients
Native T1 mapping detects both acute clinical rejection and graft dysfunction in pediatric heart transplant patients Open
In pediatric heart transplant patients, native T1 values identify acute rejection requiring treatment and may identify graft dysfunction. CMR shows promise as an important tool for evaluation of cardiac grafts in children, with T1 imaging …
View article: Dynamic PEEP Study: A Non-Invasive Diagnostic Exam to Assess for Effective PEEP in Fragile Children With Severe BPD
Dynamic PEEP Study: A Non-Invasive Diagnostic Exam to Assess for Effective PEEP in Fragile Children With Severe BPD Open
ObjectiveTracheobronchomalacia (TBM) is common in neonates with bronchopulmonary dysplasia (BPD) and is associated with higher morbidity. This study evaluates the value of a CT protocol to assess the degree of TBM and gauge the adequacy of…
View article: Inhaled Nitric Oxide Use and Outcomes in Critically Ill Children With a History of Prematurity
Inhaled Nitric Oxide Use and Outcomes in Critically Ill Children With a History of Prematurity Open
INO was used differently in early preterm subjects. Clinical trials that evaluate INO use should have standardized oxygenation deficit thresholds for initiation of therapy and should consider stratifying by early preterm status.
View article: Survival and Hemodynamics During Pediatric Cardiopulmonary Resuscitation for Bradycardia and Poor Perfusion Versus Pulseless Cardiac Arrest
Survival and Hemodynamics During Pediatric Cardiopulmonary Resuscitation for Bradycardia and Poor Perfusion Versus Pulseless Cardiac Arrest Open
Objectives: The objective of this study was to compare survival outcomes and intra-arrest arterial blood pressures between children receiving cardiopulmonary resuscitation for bradycardia and poor perfusion and those with pulseless cardiac…
View article: Inhaled Nitric Oxide Use in Pediatric Hypoxemic Respiratory Failure*
Inhaled Nitric Oxide Use in Pediatric Hypoxemic Respiratory Failure* Open
Objectives: To characterize contemporary use of inhaled nitric oxide in pediatric acute respiratory failure and to assess relationships between clinical variables and outcomes. We sought to study the relationship of inhaled nitric oxide re…
View article: Plasma and Urinary FGF-2 and VEGF-A Levels Identify Children at Risk for Severe Bleeding after Pediatric Cardiopulmonary Bypass: A Pilot Study.
Plasma and Urinary FGF-2 and VEGF-A Levels Identify Children at Risk for Severe Bleeding after Pediatric Cardiopulmonary Bypass: A Pilot Study. Open
Severe bleeding after cardiothoracic surgery with cardiopulmonary bypass (CPB) is associated with increased morbidity and mortality in adults and children. Fibroblast Growth Factor-2 (FGF-2) and Vascular Endothelial Growth Factor-A (VEGF-A…
View article: Survival and Cardiopulmonary Resuscitation Hemodynamics Following Cardiac Arrest in Children With Surgical Compared to Medical Heart Disease*
Survival and Cardiopulmonary Resuscitation Hemodynamics Following Cardiac Arrest in Children With Surgical Compared to Medical Heart Disease* Open
Objectives: To assess the association of diastolic blood pressure cutoffs (≥ 25 mm Hg in infants and ≥ 30 mm Hg in children) during cardiopulmonary resuscitation with return of spontaneous circulation and survival in surgical cardiac versu…
View article: Ventilation Rates and Pediatric In-Hospital Cardiac Arrest Survival Outcomes*
Ventilation Rates and Pediatric In-Hospital Cardiac Arrest Survival Outcomes* Open
Objectives: The objective of this study was to associate ventilation rates during in-hospital cardiopulmonary resuscitation with 1) arterial blood pressure during cardiopulmonary resuscitation and 2) survival outcomes. Design: Prospective,…
View article: Clinical Determination of Brain Death in Children Supported by Extracorporeal Membrane Oxygenation
Clinical Determination of Brain Death in Children Supported by Extracorporeal Membrane Oxygenation Open
Clinical determination of brain death, including apnea testing, can be performed in pediatric patients supported by ECMO. The ECMO circuit can be effectively modified during apnea testing to achieve a timely rise in carbon dioxide while ma…
View article: Development of the Pediatric Extracorporeal Membrane Oxygenation Prediction Model for Risk-Adjusting Mortality*
Development of the Pediatric Extracorporeal Membrane Oxygenation Prediction Model for Risk-Adjusting Mortality* Open
Objectives: To develop a prognostic model for predicting mortality at time of extracorporeal membrane oxygenation initiation for children which is important for determining center-specific risk-adjusted outcomes. Design: Multivariable logi…
View article: Utilization of a Dual Surveillance Program to Reduce Surgical-site Infections
Utilization of a Dual Surveillance Program to Reduce Surgical-site Infections Open
Background: Surveillance plays a pivotal role in the surgical-site infections (SSIs) prevention through identifying infections, monitoring changes in infection rates, and evaluating the effectiveness of intervention strategies. Methods: Th…
View article: Risk Factors for Major Early Adverse Events Related to Cardiac Catheterization in Children and Young Adults With Pulmonary Hypertension: An Analysis of Data From the IMPACT (Improving Adult and Congenital Treatment) Registry
Risk Factors for Major Early Adverse Events Related to Cardiac Catheterization in Children and Young Adults With Pulmonary Hypertension: An Analysis of Data From the IMPACT (Improving Adult and Congenital Treatment) Registry Open
Background Cardiac catheterization is the gold standard for assessment and follow‐up of patients with pulmonary hypertension ( PH ). To date, there are limited data about the factors that influence the risk of catastrophic adverse events a…