John W. Brady
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View article: Characterization of the Sodium Multi-Vitamin Transporter in the Mosquito Anopheles stephensi and Its Capacity to Mobilize Pantothenate and Biotin
Characterization of the Sodium Multi-Vitamin Transporter in the Mosquito Anopheles stephensi and Its Capacity to Mobilize Pantothenate and Biotin Open
Pantothenate (Pan), or vitamin B5, is essential for the synthesis of co-enzyme A (CoA), acetyl-CoA, and numerous downstream physiological processes. We previously demonstrated that Pan is not only essential for mosquito survival, but also …
View article: Burkholderia cenocepacia H111 Produces a Water-Insoluble Exopolysaccharide in Biofilm: Structural Determination and Molecular Modelling
Burkholderia cenocepacia H111 Produces a Water-Insoluble Exopolysaccharide in Biofilm: Structural Determination and Molecular Modelling Open
Biofilms are a multicellular way of life, where bacterial cells are close together and embedded in a hydrated macromolecular matrix which offers a number of advantages to the cells. Extracellular polysaccharides play an important role in m…
View article: Water structuring above solutes with planar hydrophobic surfaces
Water structuring above solutes with planar hydrophobic surfaces Open
MD simulations find that planar hydrophobic solutes structure water above their surfaces differently depending on surface size, in qualitative agreement with field theory predictions, but with a transition from entropic to enthalpic-domina…
View article: Strategies to reduce end‐product inhibition in family 48 glycoside hydrolases
Strategies to reduce end‐product inhibition in family 48 glycoside hydrolases Open
Family 48 cellobiohydrolases are some of the most abundant glycoside hydrolases in nature. They are able to degrade cellulosic biomass and therefore serve as good enzyme candidates for biofuel production. Family 48 cellulases hydrolyze cel…