John C. Stevenson
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View article: Low-dose and ultra-low-dose estradiol and dydrogesterone in postmenopause: an analysis by body mass index
Low-dose and ultra-low-dose estradiol and dydrogesterone in postmenopause: an analysis by body mass index Open
Oral, ultra-low-dose continuous combined E0.5 mg/D2.5 mg and low-dose continuous combined E1 mg/D5 mg alleviated postmenopausal VMS compared with placebo, irrespective of BMI.
View article: Ultra-low-dose continuous combined estradiol and dydrogesterone in postmenopausal women: A pooled safety and tolerability analysis
Ultra-low-dose continuous combined estradiol and dydrogesterone in postmenopausal women: A pooled safety and tolerability analysis Open
Objective: To assess the safety and tolerability of ultra-low dose estradiol and dydrogesterone (E0.5 mg/D2.5 mg) among postmenopausal women. Methods: This pooled analysis of data from three clinical studies assessed the effe…
View article: Death, Taxes, and Inequality. Can a Minimal Model Explain Real Economic Inequality?
Death, Taxes, and Inequality. Can a Minimal Model Explain Real Economic Inequality? Open
Income inequality and redistribution policies are modeled with a minimal, endogenous model of a simple foraging economy. Significant income inequalities emerge from the model for populations of equally capable individuals presented with eq…
View article: Low Total Fertility in Simple Economic Systems
Low Total Fertility in Simple Economic Systems Open
Low total fertility rates throughout the world have lead to concerns about economic growth, military security, international political power, environment impacts, and quality of life. Overall total fertility rates of today's societies are …
View article: Local Sharing and Sociality Effects on Wealth Inequality in a Simple Artificial Society
Local Sharing and Sociality Effects on Wealth Inequality in a Simple Artificial Society Open
Redistribution of resources within a group as a method to reduce wealth inequality is a current area of debate. The evolutionary path to or away from wealth sharing is also a subject of active research. In order to investigate effects and …
View article: Towards Eusociality Using an Inverse Agent Based Model
Towards Eusociality Using an Inverse Agent Based Model Open
The emergence of eusocial species is both very rare in evolutionary history and results in remarkably successful species. By inverting an agent based model, agent rules are discovered that display behaviors characteristic of eusocial speci…
View article: Menopause-associated risk of cardiovascular disease
Menopause-associated risk of cardiovascular disease Open
Cardiovascular disease (CVD) is of major concern in women entering menopause. The changing hormonal milieu predisposes them to increased CVD risk, due to a constellation of risk factors, such as visceral obesity, atherogenic dyslipidemia, …
View article: Competitive Exclusion in an Artificial Foraging Ecosystem
Competitive Exclusion in an Artificial Foraging Ecosystem Open
Artificial ecosystems provide an additional experimental tool to support laboratory work, field work, and theoretical development in competitive exclusion research. A novel application of a spatiotemporal agent based model is presented whi…
View article: World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2021)
World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2021) Open
View article: Dynamics of Wealth Inequality in Simple Artificial Societies
Dynamics of Wealth Inequality in Simple Artificial Societies Open
A simple generative model of a foraging society generates significant wealth inequalities from identical agents on an equal opportunity landscape. These inequalities arise in both equilibrium and non-equilibrium regimes with some societies…
View article: David McKay Hart, MD, FRCS (Glasgow), FRCOG
David McKay Hart, MD, FRCS (Glasgow), FRCOG Open
David McKay Hart, who died last year aged 84, was a distinguished Consultant Obstetrician and Gynecologist in Glasgow, Scotland. He qualified in medicine at the University of Glasgow and decided to...
View article: Cardiometabolic health in premature ovarian insufficiency
Cardiometabolic health in premature ovarian insufficiency Open
Premature ovarian insufficiency (POI) is an increasing public health problem with a prevalence now approaching 4%. POI results in adverse effects on the skeleton and central nervous system as well as disturbances of metabolic and cardiolog…
View article: Progestogens as a component of menopausal hormone therapy: the right molecule makes the difference
Progestogens as a component of menopausal hormone therapy: the right molecule makes the difference Open
Optimizing menopausal hormone therapy (MHT) requires an awareness of the benefits and risks associated with the available treatments. This narrative review, which is based on the proceedings of an Advisory Board meeting and supplemented by…
View article: Hormone replacement therapy in diabetes
Hormone replacement therapy in diabetes Open
View article: Engaging Schools with InSight Data
Engaging Schools with InSight Data Open
<p>After a 6-month flight to Mars and a successful landing, InSight has deployed SEIS … its seismometer designed to sit on the Martian surface. The goal of this mission is to investigate the dynamics of Martian seismic acti…
View article: EMAS position statement: Predictors of premature and early natural menopause
EMAS position statement: Predictors of premature and early natural menopause Open
View article: Hormone therapy for first-line management of menopausal symptoms: Practical recommendations
Hormone therapy for first-line management of menopausal symptoms: Practical recommendations Open
Hormone therapy use has undergone dramatic changes over the past 20 years. Widespread use of hormone therapy in the 1980s and 1990s came to an abrupt halt in the early 2000s after initial findings of the Women’s Health Initiative trial wer…
View article: Menopause and diabetes: EMAS clinical guide
Menopause and diabetes: EMAS clinical guide Open
View article: Calcium in the prevention of postmenopausal osteoporosis: EMAS clinical guide
Calcium in the prevention of postmenopausal osteoporosis: EMAS clinical guide Open
View article: Drug holidays from bisphosphonates and denosumab in postmenopausal osteoporosis: EMAS position statement
Drug holidays from bisphosphonates and denosumab in postmenopausal osteoporosis: EMAS position statement Open
View article: Menopausal Hormone Therapy and Type 2 Diabetes Prevention: Evidence, Mechanisms, and Clinical Implications
Menopausal Hormone Therapy and Type 2 Diabetes Prevention: Evidence, Mechanisms, and Clinical Implications Open
Type 2 diabetes has reached epidemic proportions in the United States. Large, randomized controlled trials suggest that menopausal hormone therapy (MHT) delays the onset of type 2 diabetes in women. However, the mechanisms and clinical imp…
View article: The effect of hormone replacement therapy and tibolone on lipoprotein (a) concentrations in postmenopausal women: A systematic review and meta-analysis
The effect of hormone replacement therapy and tibolone on lipoprotein (a) concentrations in postmenopausal women: A systematic review and meta-analysis Open
View article: Back to the future: Hormone replacement therapy as part of a prevention strategy for women at the onset of menopause
Back to the future: Hormone replacement therapy as part of a prevention strategy for women at the onset of menopause Open
View article: EMAS recommendations for conditions in the workplace for menopausal women
EMAS recommendations for conditions in the workplace for menopausal women Open
View article: EMAS position statement: Testosterone replacement therapy in the aging male
EMAS position statement: Testosterone replacement therapy in the aging male Open