Joseph Cox
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View article: Canadian guideline on HIV pre- and postexposure prophylaxis: 2025 update
Canadian guideline on HIV pre- and postexposure prophylaxis: 2025 update Open
Multiple safe, effective PrEP and PEP regimens are now available in Canada, making it increasingly possible to find suitable options for all who could benefit. Implementation of this guideline should expand access to biomedical HIV prevent…
View article: How gay, bisexual and other men who have sex with men living with HIV experience sexual dysfunction: a thematic analysis of interviews in Montreal, Canada
How gay, bisexual and other men who have sex with men living with HIV experience sexual dysfunction: a thematic analysis of interviews in Montreal, Canada Open
Background Sexual dysfunction (SD) is prevalent, yet underaddressed, among gay, bisexual and other men who have sex with men (GBM) living with HIV. We aimed at exploring the perceived causes and effects of SD from the perspective of Montre…
View article: Estimation de la taille de la population des personnes qui utilisent des drogues par injection au Canada, 2021
Estimation de la taille de la population des personnes qui utilisent des drogues par injection au Canada, 2021 Open
View article: Estimating the population size of people who inject drugs in Canada, 2021
Estimating the population size of people who inject drugs in Canada, 2021 Open
View article: Sexual dysfunction care needs of gay, bisexual, and other men who have sex with men living with <scp>HIV</scp> in Montreal, Canada
Sexual dysfunction care needs of gay, bisexual, and other men who have sex with men living with <span>HIV</span> in Montreal, Canada Open
Objectives Sexual dysfunction (SD) is common among gay, bisexual and other men who have sex with men (GBM) with HIV, yet little is known about their views on SD care. We explored these views to inform patient‐centred SD care to improve car…
View article: Risk of perioperative mortality and venous thromboembolism after total hip or knee arthroplasty with recent COVID-19 infection: an observational study from the Kaiser Permanente Northern California Database
Risk of perioperative mortality and venous thromboembolism after total hip or knee arthroplasty with recent COVID-19 infection: an observational study from the Kaiser Permanente Northern California Database Open
Background and purpose: Limited data exist on venous thromboembolism (VTE) and mortality risk in patients undergoing primary total hip (THA) or knee arthroplasty (TKA) following recent COVID-19 infection. We aimed to evaluate whether the t…
View article: Distinct Gut Microbiota Signatures Are Associated with Severity of Metabolic Dysfunction-Associated Steatotic Liver Disease in People with HIV
Distinct Gut Microbiota Signatures Are Associated with Severity of Metabolic Dysfunction-Associated Steatotic Liver Disease in People with HIV Open
The progression of metabolic dysfunction-associated steatotic liver disease (MASLD) to severe forms, including metabolic dysfunction-associated steatohepatitis (MASH) and liver fibrosis, involves metabolic dysfunction, genetics, and gut dy…
View article: Estimated prevalence of hepatitis B and C among immigrants in Canada
Estimated prevalence of hepatitis B and C among immigrants in Canada Open
This is the first study to estimate the burden of HBV and HCV among immigrants at the national level in Canada. The results show that the prevalence of viral hepatitis among immigrants is higher than the general Canadian population. Howeve…
View article: Estimations nationales de l'hépatite B et de l'hépatite C pour 2021 : mesurer les progrès réalisés par le Canada vers l'élimination de l'hépatite virale en tant que problème de santé publique
Estimations nationales de l'hépatite B et de l'hépatite C pour 2021 : mesurer les progrès réalisés par le Canada vers l'élimination de l'hépatite virale en tant que problème de santé publique Open
View article: National hepatitis B and C estimates for 2021: Measuring Canada’s progress towards eliminating viral hepatitis as a public health concern
National hepatitis B and C estimates for 2021: Measuring Canada’s progress towards eliminating viral hepatitis as a public health concern Open
While the overall viral hepatitis burden is low in the general Canadian population, these estimates indicate that certain populations and communities remain disproportionately affected. Although Canada has met some of the 2025 targets, mor…
View article: Factors influencing the acceptability of hepatitis C screening among people with experience of incarceration in Quebec, Canada: A qualitative descriptive study guided by the Theoretical Domains Framework
Factors influencing the acceptability of hepatitis C screening among people with experience of incarceration in Quebec, Canada: A qualitative descriptive study guided by the Theoretical Domains Framework Open
The TDF was useful in identifying factors associated with the acceptability of HCV screening among PWEI. Future interventions should seek to leverage peer networks, integrate point-of-care HCV testing, and provide whole-of-sector education…
View article: A pre-post study of the impact of a multidisciplinary model of care on linkage to hepatitis C care following release from prison: The Beyond Prison Walls study
A pre-post study of the impact of a multidisciplinary model of care on linkage to hepatitis C care following release from prison: The Beyond Prison Walls study Open
A multidisciplinary model of care increased linkage to HCV care among untreated individuals released from prison. Future interventions should support similar models, leveraging social support networks to maximize continuity of care.
View article: Identifying Syndemic Factors and Their Effect on HIV Sexual Risk Behavior Among Gay, Bisexual and Other Men Who Have Sex with Men in Vancouver, Montreal and Toronto
Identifying Syndemic Factors and Their Effect on HIV Sexual Risk Behavior Among Gay, Bisexual and Other Men Who Have Sex with Men in Vancouver, Montreal and Toronto Open
View article: Sexually transmitted and blood-borne infections in transgender and non-binary people in Canada: A scoping review
Sexually transmitted and blood-borne infections in transgender and non-binary people in Canada: A scoping review Open
In the 2021 census, 100,815 people in Canada aged 15 and older identified as transgender or non-binary. Globally, transgender people are disproportionately burdened by several Sexually Transmitted and Blood-Borne Infections (STBBIs) but li…
View article: Proposed approaches for public health surveillance: A literature review for the Canadian National HIV Surveillance Program
Proposed approaches for public health surveillance: A literature review for the Canadian National HIV Surveillance Program Open
In future work, lessons resulting from the literature review will be combined with evidence from other components of the overall review of Canada's HIV surveillance system. Together, this information will be further assessed and prioritize…
View article: Predicting fatal drug poisoning among people living with HIV-HCV co-infection
Predicting fatal drug poisoning among people living with HIV-HCV co-infection Open
Background: Drug poisoning (overdose) is a public health crisis, particularly among people living with HIV and hepatitis C (HCV) co-infection. Identifying potential predictors of drug poisoning could help decrease drug-related deaths. Meth…
View article: Progress toward hepatitis C virus elimination among people living with HIV–hepatitis C virus coinfection in Canada
Progress toward hepatitis C virus elimination among people living with HIV–hepatitis C virus coinfection in Canada Open
Background: Direct-acting antivirals (DAAs) for hepatitis C virus (HCV) were approved in Canada in 2013. By 2018, treatment restrictions had been lifted in all provinces, making DAAs universally accessible. Here, we aim to assess progress …
View article: Impact of interventions on mpox transmission during the 2022 outbreak in Canada: a mathematical modeling study of three different cities
Impact of interventions on mpox transmission during the 2022 outbreak in Canada: a mathematical modeling study of three different cities Open
Reduction in sexual activity, contact tracing/isolation, and vaccination all contributed to accelerating epidemic control. Early vaccination had the largest impact.
View article: Extracellular acyl-CoA-binding protein as an independent biomarker of COVID-19 disease severity
Extracellular acyl-CoA-binding protein as an independent biomarker of COVID-19 disease severity Open
Background Factors leading to severe COVID-19 remain partially known. New biomarkers predicting COVID-19 severity that are also causally involved in disease pathogenesis could improve patient management and contribute to the development of…
View article: The prevalence of HIV pre-exposure prophylaxis (HIV-PrEP) use and HIV-PrEP-to-need ratio in nine Canadian provinces, 2018–2021
The prevalence of HIV pre-exposure prophylaxis (HIV-PrEP) use and HIV-PrEP-to-need ratio in nine Canadian provinces, 2018–2021 Open
In Canada, the use of HIV-PrEP increased from 2018 to 2021 and uptake varied by age, sex and province. HIV-PrEP-to-need ratio is a useful measure to assess uptake of HIV-PrEP as a prevention strategy and could be used to explore disparitie…
View article: Does Intimate Partner Violence Increase Bacterial Sexually Transmitted Infections among Gay, Bisexual, and Other Men Who Have Sex?
Does Intimate Partner Violence Increase Bacterial Sexually Transmitted Infections among Gay, Bisexual, and Other Men Who Have Sex? Open
View article: Prévalence de l'utilisation de la prophylaxie préexposition au VIH (PPrE) et ratio PPrE-aux-besoins dans neuf provinces canadiennes, 2018–2021
Prévalence de l'utilisation de la prophylaxie préexposition au VIH (PPrE) et ratio PPrE-aux-besoins dans neuf provinces canadiennes, 2018–2021 Open
View article: Understanding Perceptions of Hepatitis C and Its Management Among People with Experience of Incarceration in Quebec, Canada: A Qualitative Study Guided by the Common Sense Self-Regulation Model
Understanding Perceptions of Hepatitis C and Its Management Among People with Experience of Incarceration in Quebec, Canada: A Qualitative Study Guided by the Common Sense Self-Regulation Model Open
Hepatitis C virus (HCV) disproportionately affects certain sub-populations, including people with experience of incarceration (PWEI). Little is known about how perceptions of HCV and treatment have changed despite simplifications in testin…
View article: Feasibility and Acceptability of Using an Electronic Patient-Reported Outcome Measure via a Patient Portal in HIV care
Feasibility and Acceptability of Using an Electronic Patient-Reported Outcome Measure via a Patient Portal in HIV care Open
CONTEXT: Adherence to antiretrovirals (ART) is essential for people with HIV (PWH), but many face barriers. The I-Score is a new electronic patient-reported outcome measure (ePROM) of ART adherence barriers to be used in HIV care. OBJECTIV…
View article: Exploring the link between sociodemographic factors and barriers to adherence: survey data collected from people with HIV
Exploring the link between sociodemographic factors and barriers to adherence: survey data collected from people with HIV Open
CONTEXT: At-risk subpopulations of people with HIV (PWH) in Montreal may experience sub-optimal adherence to antiretroviral therapy (ART) due to barriers. However, what barriers these subpopulations disproportionately face remains unclear.…
View article: Clinical outcomes of administering an ePROM of barriers to adherence to ART to people with HIV through a patient portal
Clinical outcomes of administering an ePROM of barriers to adherence to ART to people with HIV through a patient portal Open
CONTEXT: Adherence to antiretrovirals (ART) by people with HIV (PWH) is crucial, however, many face obstacles that go undiscussed with health professionals. We used the patient portal (Opal) to administer the I-Score, a 7-item electronic p…
View article: Perceived patient navigator services and characteristics to address barriers to linkage to hepatitis C care among people released from provincial prison in Quebec, Canada
Perceived patient navigator services and characteristics to address barriers to linkage to hepatitis C care among people released from provincial prison in Quebec, Canada Open
Interventions that seek to improve linkage to HCV care for people following release from prison should address many levels (individual, interpersonal, and policy) of the SEM. While people experience several competing priorities post-releas…
View article: The first <scp>AI</scp>‐based <scp>Chatbot</scp> to promote <scp>HIV</scp> self‐management: A mixed methods usability study
The first <span>AI</span>‐based <span>Chatbot</span> to promote <span>HIV</span> self‐management: A mixed methods usability study Open
Background We developed MARVIN, an artificial intelligence (AI)‐based chatbot that provides 24/7 expert‐validated information on self‐management‐related topics for people with HIV. This study assessed (1) the feasibility of using MARVIN, (…
View article: Implementing a Patient Portal for the Remote Follow-Up of Self-Isolating Patients With COVID-19 Infection Through Patient and Stakeholder Engagement (the Opal-COVID Study): Mixed Methods Pilot Study
Implementing a Patient Portal for the Remote Follow-Up of Self-Isolating Patients With COVID-19 Infection Through Patient and Stakeholder Engagement (the Opal-COVID Study): Mixed Methods Pilot Study Open
Background The COVID-19 pandemic was an unprecedent challenge to public health systems, with 95% of cases in Quebec sent home for self-isolation. To ensure continuous care, we implemented an intervention supported by a patient portal (Opal…
View article: Prevalence of Oral Human Papillomavirus Infection Among Urban Gay, Bisexual, and Other Men Who Have Sex With Men in Canada, 2017–2019
Prevalence of Oral Human Papillomavirus Infection Among Urban Gay, Bisexual, and Other Men Who Have Sex With Men in Canada, 2017–2019 Open
Background Oral human papillomavirus (HPV) infections are a leading cause of oropharyngeal cancers. In 2015 and 2016, HPV vaccines became publicly funded for gay, bisexual, and other men who have sex with men (GBM) under 27 years of age in…