John Franzone
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View article: 101. Patients with Carbapenem-resistant <i>Klebsiella aerogenes</i> and <i>Enterobacter cloacae</i> complex Colonization or Infection Have Different Baseline Characteristics but Similar Mortality and Clinical Outcomes
101. Patients with Carbapenem-resistant <i>Klebsiella aerogenes</i> and <i>Enterobacter cloacae</i> complex Colonization or Infection Have Different Baseline Characteristics but Similar Mortality and Clinical Outcomes Open
Background Recently, comparative phylogenetics dictated the formerly named Enterobacter aerogenes be separated from the genus Enterobacter and renamed Klebsiella aerogenes (KA); however, it remains unclear whether the genotypic differences…
View article: Current treatment options for pneumonia caused by carbapenem-resistant Acinetobacter baumannii
Current treatment options for pneumonia caused by carbapenem-resistant Acinetobacter baumannii Open
PURPOSE OF REVIEW: The purpose of this review is to briefly summarize the challenges associated with the treatment of pneumonia caused by carbapenem-resistant Acinetobacter baumannii (CRAB), discuss its carbapenem-resistance, and review th…
View article: Rationale and design of the prone position and respiratory outcomes in non-intubated COVID-19 patients: The "PRONE" study
Rationale and design of the prone position and respiratory outcomes in non-intubated COVID-19 patients: The "PRONE" study Open
View article: Current treatment options for pneumonia caused by carbapenem-resistant Acinetobacter baumannii
Current treatment options for pneumonia caused by carbapenem-resistant Acinetobacter baumannii Open
Purpose of review The purpose of this review is to briefly summarize the challenges associated with the treatment of pneumonia caused by carbapenem-resistant Acinetobacter baumannii (CRAB), discuss its carbapenem-resistance, and review the…
View article: Microbial Cell-Free DNA Identifies the Causative Pathogen in Infective Endocarditis and Remains Detectable Longer Than Conventional Blood Culture in Patients with Prior Antibiotic Therapy
Microbial Cell-Free DNA Identifies the Causative Pathogen in Infective Endocarditis and Remains Detectable Longer Than Conventional Blood Culture in Patients with Prior Antibiotic Therapy Open
Background The diagnosis of infective endocarditis (IE) can be difficult, particularly if blood cultures fail to yield a pathogen. This study evaluates the potential utility of microbial cell-free DNA (mcfDNA) as a tool to identify the mic…
View article: Efficacy and safety of two neutralising monoclonal antibody therapies, sotrovimab and BRII-196 plus BRII-198, for adults hospitalised with COVID-19 (TICO):a randomised controlled trial
Efficacy and safety of two neutralising monoclonal antibody therapies, sotrovimab and BRII-196 plus BRII-198, for adults hospitalised with COVID-19 (TICO):a randomised controlled trial Open
BackgroundWe aimed to assess the efficacy and safety of two neutralising monoclonal antibody therapies (sotrovimab [Vir Biotechnology and GlaxoSmithKline] and BRII-196 plus BRII-198 [Brii Biosciences]) for adults admitted to hospital for C…
View article: Rationale and design of the Prone Position and Respiratory Outcomes in Non-intubated COVID-19 PatiEnts: The “PRONE” Study
Rationale and design of the Prone Position and Respiratory Outcomes in Non-intubated COVID-19 PatiEnts: The “PRONE” Study Open