John G. Webb
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View article: Use of Partial Splenic Embolization Following a Transjugular Intrahepatic Portosystemic Shunt to Reduce Persistent Portal Hypertension Sequelae
Use of Partial Splenic Embolization Following a Transjugular Intrahepatic Portosystemic Shunt to Reduce Persistent Portal Hypertension Sequelae Open
Transjugular intrahepatic portosystemic shunt (TIPS) placement is a well-established intervention for portal hypertension. However, some patients experience persistent complications such as encephalopathy, ascites, or thrombocytopenia, esp…
View article: Efficacy and Safety of Transcatheter Mitral Valve Edge-to-Edge Repair with a MitraClip Device in Real-World Canadian Practice
Efficacy and Safety of Transcatheter Mitral Valve Edge-to-Edge Repair with a MitraClip Device in Real-World Canadian Practice Open
In this first national registry of patients undergoing M-TEER in Canada, M-TEER resulted in a sustained reduction in MR and was associated with reduced HF hospitalizations and improvement in NYHA functional class, with a high degree of saf…
View article: Late referrals and high mortality in tricuspid regurgitation: a call for timely intervention
Late referrals and high mortality in tricuspid regurgitation: a call for timely intervention Open
Aims Tricuspid regurgitation (TR) is associated with increased morbidity and mortality. The optimal timing for referral and intervention remains uncertain. To evaluate outcomes in patients with TR referred for tricuspid valve intervention.…
View article: Late arrhythmic burden in patients with left bundle branch block after TAVR with the Evolut valve
Late arrhythmic burden in patients with left bundle branch block after TAVR with the Evolut valve Open
Aims Arrhythmic burden after discharge in patients with new-onset persistent left bundle branch block (NOP-LBBB) following transcatheter aortic valve replacement (TAVR) with Evolut devices remains largely unknown. The aim of this study is …
View article: Balloon-Predilatation Followed by Transcatheter Aortic Valve (TAV)-in-TAV Procedure for Transvalvular and Paravalvular Regurgitation
Balloon-Predilatation Followed by Transcatheter Aortic Valve (TAV)-in-TAV Procedure for Transvalvular and Paravalvular Regurgitation Open
View article: Impact of Sheath Type on Vascular and Bleeding Complications After Transcatheter Aortic Valve Replacement: A Post Hoc Analysis From the MARVEL Registry Study
Impact of Sheath Type on Vascular and Bleeding Complications After Transcatheter Aortic Valve Replacement: A Post Hoc Analysis From the MARVEL Registry Study Open
Background Vascular and bleeding complications remain a concern after transfemoral transcatheter aortic valve replacement (TAVR). The impact of the sheath type on these complications remains unclear. Methods The prospective MARVEL registry…
View article: Managing Multivalvular Bioprosthetic Failure and a Hidden Aortic Root–Left Ventricular Outflow Tract Fistula With a Transcatheter Approach: Balancing Risk and Intervention
Managing Multivalvular Bioprosthetic Failure and a Hidden Aortic Root–Left Ventricular Outflow Tract Fistula With a Transcatheter Approach: Balancing Risk and Intervention Open
View article: Mitral regurgitation evolution after transcatheter tricuspid valve interventions—a sub-analysis of the TriValve registry
Mitral regurgitation evolution after transcatheter tricuspid valve interventions—a sub-analysis of the TriValve registry Open
Aims Transcatheter tricuspid valve interventions (TTVI) are increasingly used to treat patients with significant tricuspid regurgitation (TR). The evolution of concurrent mitral regurgitation (MR) severity after TTVI is currently unknown a…
View article: Summary: International consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and research purposes
Summary: International consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and research purposes Open
View article: Double-tap to treat paravalvular leak in high-risk annuli
Double-tap to treat paravalvular leak in high-risk annuli Open
View article: Concomitant left atrial appendage occlusion in patients undergoing mitral transcatheter edge-to-edge repair: pros and cons
Concomitant left atrial appendage occlusion in patients undergoing mitral transcatheter edge-to-edge repair: pros and cons Open
View article: An Optimized Assessment Pathway for Remote Patients: The Vancouver Facilitated Transcatheter Aortic Valve Implantation Program
An Optimized Assessment Pathway for Remote Patients: The Vancouver Facilitated Transcatheter Aortic Valve Implantation Program Open
View article: Sex-differences in Newly Diagnosed Severe Aortic Stenosis in British Columbia (B.C.) between 2012 - 2022
Sex-differences in Newly Diagnosed Severe Aortic Stenosis in British Columbia (B.C.) between 2012 - 2022 Open
Background Despite its high prevalence, little is known about the effect of sex on the management and outcomes of aortic stenosis (AS). We sought to characterize the effect of sex on the clinical evaluation for and provision of aortic valv…
View article: Defining high bleeding risk in patients undergoing transcatheter aortic valve implantation: a VARC-HBR consensus document
Defining high bleeding risk in patients undergoing transcatheter aortic valve implantation: a VARC-HBR consensus document Open
The identification and management of patients at high bleeding risk (HBR) undergoing transcatheter aortic valve implantation (TAVI) are of major importance, but the lack of standardised definitions is challenging for trial desi…
View article: Feasibility and Utility of Anatomical and Physiological Evaluation of Coronary Disease With Cardiac CT in Severe Aortic Stenosis (FUTURE-AS Registry): Rationale and Design
Feasibility and Utility of Anatomical and Physiological Evaluation of Coronary Disease With Cardiac CT in Severe Aortic Stenosis (FUTURE-AS Registry): Rationale and Design Open
FUTURE-AS will characterize the utility, safety, and feasibility of CTCA and FFRCT for coronary assessment pre-TAVR.
View article: Redo-TAVI with the ACURATE neo2 and Prime XL for balloon-expandable transcatheter heart valve failure
Redo-TAVI with the ACURATE neo2 and Prime XL for balloon-expandable transcatheter heart valve failure Open
Redo-TAVI with an ACn2/AC XL within an S3 has favourable hydrodynamic performance and less pinwheeling compared to an S3 in S3. This comes at the price of a taller neoskirt.
View article: Resumen: Consenso internacional para la nomenclatura y clasificación de la válvula aórtica bicúspide congénita y su aortopatía, con fines clínicos, quirúrgicos, intervencionistas y de investigación
Resumen: Consenso internacional para la nomenclatura y clasificación de la válvula aórtica bicúspide congénita y su aortopatía, con fines clínicos, quirúrgicos, intervencionistas y de investigación Open
This consensus of nomenclature and classification for congenital bicuspid aortic valve and its aortopathy is evidence-based and intended for universal use by physicians (both pediatricians and adults), echocardiographers, advanced cardiova…
View article: ‘I want to be a member of my heart team’: Insights from patients’ experiences of minimalist transcatheter aortic valve implantation
‘I want to be a member of my heart team’: Insights from patients’ experiences of minimalist transcatheter aortic valve implantation Open
Background: Internationally, transcatheter aortic valve implantation (TAVI) is the most common approach for treating aortic stenosis. There is growing evidence to support the implementation of a streamlined clinical pathway to optimise out…
View article: Impact of the COVID-19 Pandemic on Global TAVR Activity
Impact of the COVID-19 Pandemic on Global TAVR Activity Open
View article: One-year clinical outcomes of transcatheter aortic valve implantation with the latest iteration of self-expanding or balloonexpandable devices: insights from the OPERA-TAVI registry
One-year clinical outcomes of transcatheter aortic valve implantation with the latest iteration of self-expanding or balloonexpandable devices: insights from the OPERA-TAVI registry Open
One-year clinical outcomes of patients undergoing transfemoral TAVI and receiving PRO or ULTRA devices in the current clinical practice were similar, but PRO patients had higher rates of disabling stroke. Outcomes did not differ across the…
View article: Characterizing patients ineligible for mitral valve intervention: Phenotypic clustering sub-analysis from the CHOICE-MI Registry
Characterizing patients ineligible for mitral valve intervention: Phenotypic clustering sub-analysis from the CHOICE-MI Registry Open
Background/Introduction Transcatheter mitral valve replacement (TMVR) is emerging as a therapeutic option for surgcal high-risk patients with mitral regurgitation (MR). However, a large proportion of these patients are still rejected due t…
View article: Redo-TAVI with SAPIEN 3 in SAPIEN XT or SAPIEN 3 – impact of pre- and post-dilatation on final THV expansion
Redo-TAVI with SAPIEN 3 in SAPIEN XT or SAPIEN 3 – impact of pre- and post-dilatation on final THV expansion Open
When performing redo-TAVI with a 23 mm S3 inside a 23 mm SXT or S3, only the S3 in S3 with the use of pre- and post-dilatation reached full expansion. This underlines the importance of CT assessment of THV expansion and the role of pre-/po…
View article: Redo-TAVI with a balloon-expandable valve and the impact of index transcatheter aortic valve design
Redo-TAVI with a balloon-expandable valve and the impact of index transcatheter aortic valve design Open
View article: Transfemoral tricuspid valve replacement and one-year outcomes: the TRISCEND study
Transfemoral tricuspid valve replacement and one-year outcomes: the TRISCEND study Open
Background and Aims For patients with symptomatic, severe tricuspid regurgitation (TR), early results of transcatheter tricuspid valve (TV) intervention studies have shown significant improvements in functional status and quality of life a…
View article: Case Report: Stretching the limits—late valvuloplasty for THV dysfunction following redo mitral valve-in-valve implantation
Case Report: Stretching the limits—late valvuloplasty for THV dysfunction following redo mitral valve-in-valve implantation Open
Late balloon valvuloplasty can be used to treat under-expansion-related transcatheter heart valve (THV) dysfunction. Whether this can be performed following redo-THV implantation is unknown. Herein, we report a case of a 72-year-old male p…
View article: Sex-Related Outcomes of Transcatheter Aortic Valve Implantation with Self-Expanding or Balloon-Expandable Valves: Insights from the OPERA-TAVI Registry
Sex-Related Outcomes of Transcatheter Aortic Valve Implantation with Self-Expanding or Balloon-Expandable Valves: Insights from the OPERA-TAVI Registry Open
Background Evidence regarding sex-related differences in response to transcatheter aortic valve implantation according to the valve type is lacking. This study sought to evaluate the impact of sex on the treatment effect of Evolut-PRO/PRO+…
View article: TRI-SCORE and benefit of intervention in patients with severe tricuspid regurgitation
TRI-SCORE and benefit of intervention in patients with severe tricuspid regurgitation Open
Background and aims Benefit of tricuspid regurgitation (TR) correction and timing of intervention are unclear. This study aimed to compare survival rates after surgical or transcatheter intervention to conservative management according to …
View article: Early mobilization after transcatheter aortic valve implantation: observational cohort study
Early mobilization after transcatheter aortic valve implantation: observational cohort study Open
Aims Early mobilization is associated with improved outcomes in hospitalized older patients. We sought to determine the effect of a nurse-led protocol on mobilization 4 h after transfemoral transcatheter aortic valve implantation (TAVI) ac…
View article: Transcatheter aortic valve implantation in patients with extra-small aortic annuli
Transcatheter aortic valve implantation in patients with extra-small aortic annuli Open
TAVI is a safe and feasible treatment in patients with extra-SAA with a high rate of technical success. The use of SEV was associated with a lower rate of intraprocedural complications, higher device success at 30 days and better haemodyna…
View article: Bioprosthetic Valve Remodeling in Nonfracturable Surgical Valves
Bioprosthetic Valve Remodeling in Nonfracturable Surgical Valves Open